Disseminated Mycobacterium avium complex Infection following CD3/CD20 Bispecific Antibody Therapy in a Patient with Follicular Lymphoma

IF 4.7 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-08-08 DOI:10.1093/ofid/ofae460
J. Little, Rocio M Hurtado, Nicholas Boire, Lindsey R. Baden, A. Laga, Ann W Silk, Caron A Jacobson
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Abstract

Infections remain a major concern following bispecific antibody (BsAb) therapy but are not well described in pivotal trials. We present the first well documented case of a classic but rare opportunistic infection, disseminated Mycobacterium avium complex, in a patient receiving BsAb therapy.
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一名滤泡性淋巴瘤患者接受 CD3/CD20 双特异性抗体治疗后出现播散性分枝杆菌复合体感染
感染仍然是双特异性抗体(BsAb)治疗后的一个主要问题,但在关键试验中并没有得到很好的描述。我们介绍了第一例有据可查的典型但罕见的机会性感染病例,即在接受双特异性抗体治疗的患者中发生的播散性复合分枝杆菌感染。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
期刊介绍: ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/​Abstracted: Web of Science SCIE Scopus CAS INSPEC Portico
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