The administration of sea hare gonad and moringa leaf formula increases body weight hemoglobin in female Wistar rats

Abstract

Sea hare gonad and moringa leaf contain essential nutrients for growth and tissue formation and have physiological effects on the body. The research was to study the effects of sea hare gonad flour and moringa leaf flour formula on body weight and Hemoglobin (Hb) levels in female Wistar anemic rats. This research was conducted in a laboratory using a randomized control pretest-posttest design. The study sample consisted of 30 female Wistar rats (Rattus norvegicus) aged 5-7 months and weighing 100-150 g, all of which were anemic. The rats were divided into five treatment groups: K+ received 1.1 mg/week of iron supplementation, K- received no treatment, F1 received 3 g of sea hare gonad formula, F2 received 3 g of sea hare gonad formula and 1 g of moringa leaf flour, and F3 received 3 g of sea hare gonad formula and 2 g of moringa leaf flour. The intervention lasted for 24 days, and measurements of body weight and Hb levels were taken before and after the intervention. The change in body weight before and after the intervention in each group was as follows: K-=51.5±17.1 g, K+=-41.2±2.6 g, F1=14.3±5.7 g, F2=30.4±8.6 g, and F3=55.1±16.2 g. There was a significant difference in the increase in body weight among the groups (p=0.002). Hb levels also increased after the intervention, with changes as follows: K-=-2.56±0.95 g, K+=9.10±1.87 g, F1=7.10±1.2 g, F2=8.68±0.22 g, and F3=8.98±2.7 g. There was a significant difference in the increase in Hb levels among the intervention groups (p=0.000). The administration of sea hare gonad formula and moringa leaf flour can increase body weight and Hb levels in female anemic rats. This finding suggests the potential use of these ingredients as beneficial nutritional supplements to improve nutritional status in individuals with anemia.