New Chalcone Derivative from Persea americana and Its Anti-Tyrosinase Activity

Abstract

Caneeracone A (1), a new chalcone derivative, together with three known compounds (2–4), was isolated from the seeds of Persea americana Mill. (buccaneer avocado). The structures of these compounds were established by spectroscopic methods including 1D and 2D NMR experiments. Compound 1 exhibited a potent tyrosinase activity with an IC₅₀ of 38.29 μM.