Biotransformation of natural compounds to create useful medicinal products

IF 7.3 2区 生物学 Q1 PLANT SCIENCES Phytochemistry Reviews Pub Date : 2024-08-03 DOI:10.1007/s11101-024-10002-8
Akbar Esmaeili
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Abstract

Bioconversion holds significant value across global industries, particularly in commercializing food and drug waste. The biotransformation of chitosan into valuable food products underscores its versatile applications. This process involves microbial fermentation and enzymatic pathways, pivotal in achieving effective bioconversion. Natural compounds, integral to pharmaceutical sciences, are identified and extracted from diverse plant and animal sources. These compounds are crucial in medicine, industrial applications, and raw material production. This article focuses on microbial conversion techniques applied to natural products, which are increasingly pivotal in medicinal applications. The structural diversity resulting from microbial transformation enhances the functionality of these compounds beyond those found in animals and plants. Such compounds are utilized as renewable resources across the food and pharmaceutical sectors, serving as thickeners, gelling agents, moisture regulators, stabilizers, emulsifiers, and medicinal components. This study reviews current methodologies and emphasizes the growing importance of bioconversion in enhancing sustainability and innovation within these industries. The article explores the biotransformation of natural compounds into valuable medicinal products. It emphasizes microbial conversion techniques, highlighting their pivotal role in enhancing the functionality and sustainability of the pharmaceutical and food sectors.

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天然化合物的生物转化,创造有用的医药产品
生物转化在全球各行各业都具有重要价值,特别是在食品和药物废弃物的商业化方面。将壳聚糖生物转化为有价值的食品凸显了其用途的多样性。这一过程涉及微生物发酵和酶途径,是实现有效生物转化的关键。天然化合物是制药科学不可或缺的组成部分,可从各种植物和动物资源中鉴定和提取。这些化合物对医药、工业应用和原材料生产至关重要。本文重点介绍应用于天然产品的微生物转化技术,天然产品在医药应用中的地位日益重要。微生物转化产生的结构多样性增强了这些化合物的功能,使其超越了动物和植物。这些化合物作为可再生资源被广泛应用于食品和医药领域,可用作增稠剂、胶凝剂、水分调节剂、稳定剂、乳化剂和药用成分。本研究回顾了当前的研究方法,并强调了生物转化在提高这些行业的可持续性和创新性方面日益重要的作用。文章探讨了将天然化合物生物转化为有价值的医药产品的过程。文章强调了微生物转化技术,突出了它们在增强制药和食品行业的功能性和可持续性方面的关键作用。
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来源期刊
Phytochemistry Reviews
Phytochemistry Reviews PLANT SCIENCES-
CiteScore
16.30
自引率
2.60%
发文量
54
审稿时长
2 months
期刊介绍: Phytochemistry Reviews is the sole review journal encompassing all facets of phytochemistry. It publishes peer-reviewed papers in six issues annually, including topical issues often stemming from meetings organized by the Phytochemical Society of Europe. Additionally, the journal welcomes original review papers that contribute to advancing knowledge in various aspects of plant chemistry, function, biosynthesis, effects on plant and animal physiology, pathology, and their application in agriculture and industry. Invited meeting papers are supplemented with additional review papers, providing a comprehensive overview of the current status across all areas of phytochemistry.
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