Use of integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study

Abstract

Burn injuries pose significant challenges in healthcare, with Integra Dermal Regeneration Template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra® in managing burn wounds. Panelists employed a modified Delphi technique to assess agreement and provide feedback on 81 initial statements covering various aspects of Integra DRT application in burn wound care over three subsequent rounds. This study was endorsed by the Italian Society of Burn Surgery (SIUST). Fourteen Heads of Burn Unit Departments participated in the Delphi process. At the end of the third round and subsequent discussion on the final statement list, the panel achieved consensus on 24 statements shaping recommendations for Integra® application across various aspects, including wound bed preparation, ADM application, definitive coverage, and complication management. The resultant 24 finalized statements from this Italian consensus offer a comprehensive and practical framework for employing Integra® Dermal Regeneration Template in burn patient care. Reflective of specific Italian expertise and practice, these recommendations supplement and refine existing literature, serving as a dynamic guide subject to periodic updates aligned with evolving evidence and experiences in the field of burn surgery.