Description of clinical profile, acute complications and glycemic control after Ramadan fasting in a Tunisian population of patients with diabetes

IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Human Nutrition and Metabolism Pub Date : 2024-07-30 DOI:10.1016/j.hnm.2024.200285

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Abstract

Aims

To assess clinical and metabolic parameters in patients with diabetes during Ramadan fasting.

Patients and method

It was a prospective evaluative study based in the National Institute of Nutrition of Tunis (Departement C) in a population of patients with diabetes prepared for fasting by education and therapeutic adjustment.

Results

140 diabetics, mainly at high and very high risk (70.7 %), were analyzed. The frequencies of hypo and hyperglycemia were 12.1 and 11.4 % respectively. The mean weight and the mean systolic and diastolic blood pressure remained stable. Fasting blood glucose and HbA1C decreased significantly (−0.7 ± 3.1 mmol/L (p = 0.009), −0.18 ± 1.1 % (p = 0.047). The mean creatinine clearance had remained stable.

Conclusion

Ramadan fasting can be well-tolerated, even for patients at high and very high risk, with an improvement in glycemic control, provided prior education and adequate therapeutic adjustment.

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描述突尼斯糖尿病患者斋月禁食后的临床概况、急性并发症和血糖控制情况

目的评估斋月禁食期间糖尿病患者的临床和代谢参数。患者和方法这是突尼斯国家营养研究所（C 部）的一项前瞻性评估研究，研究对象是通过教育和治疗调整做好禁食准备的糖尿病患者。血糖过低和过高的比例分别为 12.1% 和 11.4%。平均体重、平均收缩压和舒张压保持稳定。空腹血糖和 HbA1C 显著下降（-0.7 ± 3.1 mmol/L (p = 0.009)、-0.18 ± 1.1 % (p = 0.047)）。结论：如果事先进行教育和适当的治疗调整，即使是高风险和极高风险患者也能很好地耐受拉马丹禁食，并改善血糖控制。

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