Clinical application of real-time tumor-tracking for stereotactic volumetric modulated arc therapy for liver tumors

Naoki Miyamoto , Norio Katoh , Takahiro Kanehira , Kohei Yokokawa , Ryusuke Suzuki , Yusuke Uchinami , Hiroshi Taguchi , Daisuke Abo , Hidefumi Aoyama
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Abstract

Real-time tumor-tracking volumetric modulated arc therapy (RT-VMAT) enabling beam-gating based on continuous X-ray tracking of the three-dimensional position of internal markers is relevant for moving tumors. Dose-volume characteristics and treatment time were evaluated in ten consecutive patients who underwent liver stereotactic body radiation therapy with RT-VMAT. Target dose conformity and sparing of the stomach and the intestine were improved comparing RT-VMAT with RT-3D conformal radiotherapy. The mean treatment time for each fraction was less than 10 min. RT-VMAT could be effective, especially for targets located adjacent to organs at risk.

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实时肿瘤跟踪在立体定向容积调制弧治疗肝肿瘤中的临床应用
实时肿瘤跟踪容积调制弧治疗(RT-VMAT)可根据对内部标记物三维位置的连续 X 射线跟踪进行射束分流,这对移动肿瘤很有意义。我们对连续接受肝脏立体定向体放射治疗的十名患者的剂量-体积特征和治疗时间进行了评估。与RT-3D适形放疗相比,RT-VMAT的靶剂量适形性和对胃肠的保护得到了改善。每部分的平均治疗时间不到10分钟。RT-VMAT 疗效显著,尤其是对于邻近危险器官的靶点。
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来源期刊
Physics and Imaging in Radiation Oncology
Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation
CiteScore
5.30
自引率
18.90%
发文量
93
审稿时长
6 weeks
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