Kikuchi-Fujimoto disease in the regional lymph nodes in a patient with concurrent malignant phyllodes tumour

Human Pathology Reports Pub Date : 2024-09-01 Epub Date: 2024-07-30 DOI:10.1016/j.hpr.2024.300750
Ciara Murray , Rosemarie Tremblay-LeMay , Jan Delabie , Andrea Covelli , Susan J. Done
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引用次数: 0

Abstract

Kikuchi-Fujimoto disease (KFD, histiocytic necrotizing lymphadenitis) is a rare, benign disease in which the presenting clinical and radiological features often result in misclassification as a malignant process. We present the first report of concurrent KFD in the draining lymph nodes of a malignant phyllodes tumour, adding to the growing number of reports of KFD occurring in the context of malignancy, further compounding the existing diagnostic difficulties. An increased awareness of this condition with consideration for inclusion in the differential diagnosis of lymphadenopathy is required for improved diagnosis of this under-recognized entity.

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一名并发恶性植物瘤患者的区域淋巴结出现菊地-藤本氏病
菊池-藤本氏病(Kikuchi-Fujimoto disease,KFD,组织细胞坏死性淋巴结炎)是一种罕见的良性疾病,其临床表现和放射学特征常常导致其被误诊为恶性病变。我们首次报道了恶性蝶形花瘤引流淋巴结中并发 KFD 的病例,这使越来越多关于 KFD 与恶性肿瘤同时发生的报道更加丰富,进一步加剧了现有的诊断困难。需要提高对这种疾病的认识,并考虑将其纳入淋巴结病的鉴别诊断中,以改进对这种认识不足的实体的诊断。
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