In-situ Growth of CuO Nanoflakes on Graphitic Carbon Nitride Sheets: An Electro‐active Interface for Electrocatalytic Oxidation and Detection of Riboflavin in Food and Nutritional Supplements
{"title":"In-situ Growth of CuO Nanoflakes on Graphitic Carbon Nitride Sheets: An Electro‐active Interface for Electrocatalytic Oxidation and Detection of Riboflavin in Food and Nutritional Supplements","authors":"","doi":"10.1016/j.nanoso.2024.101284","DOIUrl":null,"url":null,"abstract":"<div><p>The altered riboflavin (RF) level is considered a biomarker for early diagnosis of human ailments and also serves as an internal marker for tracing food quality and adulteration. This necessitates the need for a sensitive, selective, and affordable method for RF estimation in real samples. RF, a biological chelating ligand, is known to have an affinity for complex formation with Cu(II) by coordinating through the electron-rich nitrogen and oxygen atoms on its structure. Motivated by this, CuO nanoflakes grown over graphitic carbon nitride (gCN) support is presented as an electroactive interface (gCN.CuNF|GCE) for electrochemical RF detection. A systematic analysis of the tailored electroactive interface is presented using HR-SEM, XRD, FT-IR, and XPS. The electrochemical analysis reveals the electro-oxidation of RF at gCN.CuNF|GCE with a 4.6 times higher current and a ∼13 mV potential shift, outlining the electro-catalytic activity of the composite material towards RF. The developed sensor exhibited a discernible peak even for 25 nM RF, showcasing an LOD of 6 nM. Furthermore, excellent selectivity for RF was observed even with potential interfering species, including cyanocobalamin. Besides detectability at the nanomolar range, excellent performance was verified for repeatability and RF analysis in food and pharmaceutical samples.</p></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":null,"pages":null},"PeriodicalIF":5.4500,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano-Structures & Nano-Objects","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352507X24001951","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Physics and Astronomy","Score":null,"Total":0}
引用次数: 0
Abstract
The altered riboflavin (RF) level is considered a biomarker for early diagnosis of human ailments and also serves as an internal marker for tracing food quality and adulteration. This necessitates the need for a sensitive, selective, and affordable method for RF estimation in real samples. RF, a biological chelating ligand, is known to have an affinity for complex formation with Cu(II) by coordinating through the electron-rich nitrogen and oxygen atoms on its structure. Motivated by this, CuO nanoflakes grown over graphitic carbon nitride (gCN) support is presented as an electroactive interface (gCN.CuNF|GCE) for electrochemical RF detection. A systematic analysis of the tailored electroactive interface is presented using HR-SEM, XRD, FT-IR, and XPS. The electrochemical analysis reveals the electro-oxidation of RF at gCN.CuNF|GCE with a 4.6 times higher current and a ∼13 mV potential shift, outlining the electro-catalytic activity of the composite material towards RF. The developed sensor exhibited a discernible peak even for 25 nM RF, showcasing an LOD of 6 nM. Furthermore, excellent selectivity for RF was observed even with potential interfering species, including cyanocobalamin. Besides detectability at the nanomolar range, excellent performance was verified for repeatability and RF analysis in food and pharmaceutical samples.
期刊介绍:
Nano-Structures & Nano-Objects is a new journal devoted to all aspects of the synthesis and the properties of this new flourishing domain. The journal is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. The journal is focused on the objects rather than on their applications. However, the research for new applications of original nano-structures & nano-objects in various fields such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine is also welcome. The scope of Nano-Structures & Nano-Objects involves: -Metal and alloy nanoparticles with complex nanostructures such as shape control, core-shell and dumbells -Oxide nanoparticles and nanostructures, with complex oxide/metal, oxide/surface and oxide /organic interfaces -Inorganic semi-conducting nanoparticles (quantum dots) with an emphasis on new phases, structures, shapes and complexity -Nanostructures involving molecular inorganic species such as nanoparticles of coordination compounds, molecular magnets, spin transition nanoparticles etc. or organic nano-objects, in particular for molecular electronics -Nanostructured materials such as nano-MOFs and nano-zeolites -Hetero-junctions between molecules and nano-objects, between different nano-objects & nanostructures or between nano-objects & nanostructures and surfaces -Methods of characterization specific of the nano size or adapted for the nano size such as X-ray and neutron scattering, light scattering, NMR, Raman, Plasmonics, near field microscopies, various TEM and SEM techniques, magnetic studies, etc .