The effects of Ar + 20 % mol. O2 buffer gas and partial oxygen pressures on phase composition and mean sizes of nanosized particles of tungsten, molybdenum, iron and copper oxides obtained using exploding wires (EW) have been investigated. The buffer gas (BG) pressure increase from 0.1 to 0.3 MPa allowed increasing the mean particle size of all oxide powders while it was kept almost constant in further increasing the pressure from 0.3 to 0.4 MPa. The increase in the buffer gas pressure provided better cooling conditions for the synthesized nanosized particles, which also contained more of high-temperature Fe2O3, WO3, and MoO3 oxides. Increasing the partial pressure of oxygen from 0.02 to 0.08 MPa did not resulted in complete oxidizing of the nanoparticles because of simultaneous increasing the mean particles size and their cooling rate. The experiments showed that the minimal BG pressure required for obtaining copper and iron oxides was 0.2 MPa, whereas for tungsten and molybdenum oxides it was 0.4 MPa. The established in these work dependencies could be of fundamental meaning for developing novel process of multi-wire EW synthesis of nanoparticles and coatings from multicomponent (high-entropy) oxides
{"title":"Effect of buffer gas pressure on phases and size of oxide nanoparticles produced by exploding wires","authors":"K.V. Suliz , S.O. Kazantsev , A.V. Pervikov , S.Yu Tarasov , M.I. Lerner","doi":"10.1016/j.nanoso.2024.101419","DOIUrl":"10.1016/j.nanoso.2024.101419","url":null,"abstract":"<div><div>The effects of Ar + 20 % mol. O<sub>2</sub> buffer gas and partial oxygen pressures on phase composition and mean sizes of nanosized particles of tungsten, molybdenum, iron and copper oxides obtained using exploding wires (EW) have been investigated. The buffer gas (BG) pressure increase from 0.1 to 0.3 MPa allowed increasing the mean particle size of all oxide powders while it was kept almost constant in further increasing the pressure from 0.3 to 0.4 MPa. The increase in the buffer gas pressure provided better cooling conditions for the synthesized nanosized particles, which also contained more of high-temperature Fe<sub>2</sub>O<sub>3</sub>, WO<sub>3</sub>, and MoO<sub>3</sub> oxides. Increasing the partial pressure of oxygen from 0.02 to 0.08 MPa did not resulted in complete oxidizing of the nanoparticles because of simultaneous increasing the mean particles size and their cooling rate. The experiments showed that the minimal BG pressure required for obtaining copper and iron oxides was 0.2 MPa, whereas for tungsten and molybdenum oxides it was 0.4 MPa. The established in these work dependencies could be of fundamental meaning for developing novel process of multi-wire EW synthesis of nanoparticles and coatings from multicomponent (high-entropy) oxides</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101419"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.nanoso.2025.101440
Haboon Ahmed Hassan, Betül Gürünlü
The purpose of this study is to investigate a sustainable and eco-friendly method of producing silver nanoparticles in the Sivas-Zara area by utilizing lanolin, a naturally occurring material that is taken from sheep wool. This study was driven by the antioxidant, antibacterial, and photocatalytic qualities of lanolin, which may have uses in cosmetics and environmental remedies. The findings demonstrate that Ultraviolet Visible Spectroscopy and Fourier Transform Infrared Spectroscopy spectroscopy were used to successfully produce and analyze silver nanoparticles. The antibacterial activity was evaluated against Staphylococcus aureus and Escherichia coli, and the antioxidant qualities were confirmed using the Folin-Ciocalteu assay. Furthermore, the methylene blue dye was efficiently degraded by photocatalysis, reducing absorbance by 79.92% in just 24 minutes. To sum up, our study shows that lanolin is a good reducing agent for making AgNPs, which have potent antioxidant, antibacterial and photocatalytic properties.
{"title":"Utilizing the lanolin of kangal-akkaraman sheep breed wool from Sivas-Zara area for silver nanoparticles synthesis and their multifaceted applications","authors":"Haboon Ahmed Hassan, Betül Gürünlü","doi":"10.1016/j.nanoso.2025.101440","DOIUrl":"10.1016/j.nanoso.2025.101440","url":null,"abstract":"<div><div>The purpose of this study is to investigate a sustainable and eco-friendly method of producing silver nanoparticles in the Sivas-Zara area by utilizing lanolin, a naturally occurring material that is taken from sheep wool. This study was driven by the antioxidant, antibacterial, and photocatalytic qualities of lanolin, which may have uses in cosmetics and environmental remedies. The findings demonstrate that Ultraviolet Visible Spectroscopy and Fourier Transform Infrared Spectroscopy spectroscopy were used to successfully produce and analyze silver nanoparticles. The antibacterial activity was evaluated against <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>, and the antioxidant qualities were confirmed using the Folin-Ciocalteu assay. Furthermore, the methylene blue dye was efficiently degraded by photocatalysis, reducing absorbance by 79.92% in just 24 minutes. To sum up, our study shows that lanolin is a good reducing agent for making AgNPs, which have potent antioxidant, antibacterial and photocatalytic properties.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101440"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143338491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nanoparticles are revolutionizing cancer treatment by overcoming the limitations of conventional drug delivery systems, which often result in significant side effects and reduced therapeutic efficacy due to non-specific targeting and poor solubility. Traditional chemotherapeutic agents can damage healthy tissues, particularly those with rapidly dividing cells, necessitating lower drug dosages and leading to disappointing survival rates. To address these challenges, nanoparticles utilize the enhanced permeability and retention (EPR) effect, allowing for improved drug accumulation in tumor tissues. Engineered nanoparticles can be designed for specific targeting by incorporating ligands that selectively bind to receptors on target cells and tumor vasculature. Additionally, stimuli-responsive nanoplatforms represent an innovative approach; these platforms remain inactive in normal conditions but become activated in the tumor environment, releasing their therapeutic payload in a controlled manner. This targeted strategy not only enhances treatment efficacy but also minimizes exposure to healthy cells. Researchers are focusing on modifying nanoparticle surfaces with biological ligands, known as active targeting, which improves absorption and facilitates stronger attachment to specific receptors on cancer cells. By concentrating on the unique features of malignancies, nanomedicine offers a more efficient method for addressing solid tumors and reduces the risk of developing resistant clonal populations of cancer cells. Overall, nanotechnology provides the potential for selective targeting of malignant cells, enhancing drug delivery and uptake while minimizing harm to healthy tissues. This paper explores the principles of nanoparticle targeting, interactions with cancer cells, and drug release mechanisms, highlighting the transformative potential of nanotechnology in advancing cancer therapies.
{"title":"Nanoparticle troopers: Infiltrating cancer cells for targeted therapies","authors":"Shivam Rajput , Rishabha Malviya , Bhupendra G. Prajapati , Sathvik Belagodu Sridhar , Javedh Shareef","doi":"10.1016/j.nanoso.2025.101453","DOIUrl":"10.1016/j.nanoso.2025.101453","url":null,"abstract":"<div><div>Nanoparticles are revolutionizing cancer treatment by overcoming the limitations of conventional drug delivery systems, which often result in significant side effects and reduced therapeutic efficacy due to non-specific targeting and poor solubility. Traditional chemotherapeutic agents can damage healthy tissues, particularly those with rapidly dividing cells, necessitating lower drug dosages and leading to disappointing survival rates. To address these challenges, nanoparticles utilize the enhanced permeability and retention (EPR) effect, allowing for improved drug accumulation in tumor tissues. Engineered nanoparticles can be designed for specific targeting by incorporating ligands that selectively bind to receptors on target cells and tumor vasculature. Additionally, stimuli-responsive nanoplatforms represent an innovative approach; these platforms remain inactive in normal conditions but become activated in the tumor environment, releasing their therapeutic payload in a controlled manner. This targeted strategy not only enhances treatment efficacy but also minimizes exposure to healthy cells. Researchers are focusing on modifying nanoparticle surfaces with biological ligands, known as active targeting, which improves absorption and facilitates stronger attachment to specific receptors on cancer cells. By concentrating on the unique features of malignancies, nanomedicine offers a more efficient method for addressing solid tumors and reduces the risk of developing resistant clonal populations of cancer cells. Overall, nanotechnology provides the potential for selective targeting of malignant cells, enhancing drug delivery and uptake while minimizing harm to healthy tissues. This paper explores the principles of nanoparticle targeting, interactions with cancer cells, and drug release mechanisms, highlighting the transformative potential of nanotechnology in advancing cancer therapies.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101453"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143430208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The green synthesis of silver-SrTiO3 (Ag-STO) nanocomposites mediated by gambir (Uncaria gambir Roxb.) leaf extract successfully produced Ag nanoparticles decorated on the surface of SrTiO3. The extract functions as a bioreductor, facilitating the formation of silver nanoparticles by reducing Ag(I) ions to Ag metal during solvothermal synthesis. Structural analysis confirmed the presence of Ag metal and morphological observations showed that the SrTiO₃ particles are below 50 nm in size and, with their surfaces decorated by Ag particles of about 7 nm in size. Fourier transform infrared spectroscopy spectrum emphasized the vibrational characteristics of the interactions between functional groups on cetyl trimethyl ammonium bromide (CTAB), serving as a capping agent, and tert-butylamine (TBA) as a mineralizer with the SrTiO₃ surface. The optical response measurement confirmed that both Ag and SrTiO₃ display their distinct absorption characteristics, indicating that the band gap energy of the resulting Ag-STO nanocomposite remains unchanged. The electrical conductivity value of Ag-STO nanocomposite reached up to 29 times higher than that of the SrTiO₃ at high temperatures.
{"title":"Synthesis of Ag-decorated SrTiO3-based nanocomposites via solvothermal method using Uncaria gambir Roxb. leaf extract as a bioreductor with enhanced electrical conductivity","authors":"Yulia Eka Putri , Puji Vajrian Pertiwi , Jumadil Khairani , Halimah Tusadiah-Z. , Diana Vanda Wellia , Dedi Satria , Tio Putra Wendari","doi":"10.1016/j.nanoso.2025.101447","DOIUrl":"10.1016/j.nanoso.2025.101447","url":null,"abstract":"<div><div>The green synthesis of silver-SrTiO<sub>3</sub> (Ag-STO) nanocomposites mediated by gambir (<em>Uncaria gambir</em> Roxb.) leaf extract successfully produced Ag nanoparticles decorated on the surface of SrTiO<sub>3</sub>. The extract functions as a bioreductor, facilitating the formation of silver nanoparticles by reducing Ag(I) ions to Ag metal during solvothermal synthesis. Structural analysis confirmed the presence of Ag metal and morphological observations showed that the SrTiO₃ particles are below 50 nm in size and, with their surfaces decorated by Ag particles of about 7 nm in size. Fourier transform infrared spectroscopy spectrum emphasized the vibrational characteristics of the interactions between functional groups on cetyl trimethyl ammonium bromide (CTAB), serving as a capping agent, and tert-butylamine (TBA) as a mineralizer with the SrTiO₃ surface. The optical response measurement confirmed that both Ag and SrTiO₃ display their distinct absorption characteristics, indicating that the band gap energy of the resulting Ag-STO nanocomposite remains unchanged. The electrical conductivity value of Ag-STO nanocomposite reached up to 29 times higher than that of the SrTiO₃ at high temperatures.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101447"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143453407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The remarkable mechanical strength, extensive surface areas, and adaptable optical characteristics of organic nanomaterials—such as fullerenes, carbon nanotubes, and graphene—make them ideal for use in nanocomposites, flexible electronics, and optoelectronic devices. But obstacles including thermal and chemical stability, environmental worries, and scalability problems prevent them from being widely used in real-world applications. By addressing these issues with better synthesis and manufacturing methods, these materials' stability, repeatability, and integration may be enhanced, opening the door for their profitable commercialization. The potential of organic nanomaterials to advance optoelectronics is investigated in this review paper.
{"title":"Advances and significances of organic nanomaterials in optoelectronic applications","authors":"Abdirizak Abdullahi Khalif , Umme Salma , MD Zonayed , Md Israfil Hossain Rimon , Mariam Akter Mimona , Md Hosne Mobarak","doi":"10.1016/j.nanoso.2024.101420","DOIUrl":"10.1016/j.nanoso.2024.101420","url":null,"abstract":"<div><div>The remarkable mechanical strength, extensive surface areas, and adaptable optical characteristics of organic nanomaterials—such as fullerenes, carbon nanotubes, and graphene—make them ideal for use in nanocomposites, flexible electronics, and optoelectronic devices. But obstacles including thermal and chemical stability, environmental worries, and scalability problems prevent them from being widely used in real-world applications. By addressing these issues with better synthesis and manufacturing methods, these materials' stability, repeatability, and integration may be enhanced, opening the door for their profitable commercialization. The potential of organic nanomaterials to advance optoelectronics is investigated in this review paper.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101420"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.nanoso.2025.101432
Adamu Mamman , Preeti Jain
Natural resource-derived nanoparticles have continued to gain popularity due to their potential application in the biomedical and other domains. This study presents an in-situ synthesis method that uses cold-macerated aqueous extract generated from Combretum glutinosum’s stem bark tissue to synthesize soft, non-aggregated, and well-dispersed Ag.0, Au.0, and Ag.0-coated-Au.0 nanoparticles. Their TEM and FESEM images demonstrated that they are soft, non-aggregated, well-dispersed, and spherically shaped particles with mean diameters of 13.10 nm and 20.00 nm for CgAgNPs and CgAg0-Au0NPs, respectively, whereas, particles of CgAuNPs exhibited the same characteristics but had variable shapes including spherical, cylindrical, triangular, pentagonal, and hexagonal with a mean diameter of 29.48 nm. Their mean hydrodynamic sizes (from DLS), core sizes (from TEM), and crystallite sizes (from PXRD) appeared in the range of 4.0–45.5 nm, which follows a trend of crystallite sizes ˂ core sized ˂ hydrodynamic sizes. Besides the crystallite sizes, PXRD analysis exposed their purity and crystallinity with average crystallite diameters (nm) of 4.49 for CgAgNPs, 9.23 for CgAuNPs, and 7.9 for CgAg0-Au0NPs. These nanoparticles are highly stable as revealed by their zeta potential values which were further supported by their hardness (դ) values obtained from the Tauc plot for the bandgap energies that followed a trend of դ= 2.495 (–29.5 mV) ˃ դ= 2.315 (–27.4 mV) ˃ դ= 1.495 (–13.2 mV) for CgAg0-Au0NPs, CgAgNPs, and CgAuNPs, respectively. The robust stability preserved their physicochemical behaviour over time and equipped them with promising biological effects. The binding potential of these nanoparticles to C.t.DNA revealed effective interaction with binding constant (Kb) values of 2.467 × 103 (CgAgNPs), 2.438 × 103 (CgAuNPs), and 2.199 × 103 (CgAg0-Au0NP), suggesting their usage as antimicrobial agents. Following this, they were investigated for antibacterial activities and the outcomes unveiled strong activity with potent IC50 of 0.05 mg/ml(50 µg./ml) over Staphylococcus aureus and 0.1 mg/ml(100 µg/ml) over Pseudomonas aeruginosa for CgAgNPs; 0.1 mg/ml(100 µg/ml) over both organisms for CgAuNPs; and 0.05 mg/ml(50 µg/ml) over both organisms for CgAg0-Au0NPs. Their stability, softness, non-aggregation, and well-dispersed nature equipped them with incredible biological effects which are credited to the synergistic potential contributed by each component.
{"title":"In-situ synthesis of soft, non-aggregated and well-dispersed Ag0, Au0 and Ag0-coated-Au0 nanoparticles using cold-macerated bark extract of Combretum glutinosum: Stability, DNA-binding, and antibacterial potential","authors":"Adamu Mamman , Preeti Jain","doi":"10.1016/j.nanoso.2025.101432","DOIUrl":"10.1016/j.nanoso.2025.101432","url":null,"abstract":"<div><div>Natural resource-derived nanoparticles have continued to gain popularity due to their potential application in the biomedical and other domains. This study presents an in-situ synthesis method that uses cold-macerated aqueous extract generated from <em>Combretum glutinosum</em>’s stem bark tissue to synthesize soft, non-aggregated, and well-dispersed Ag.<sup>0</sup>, Au.<sup>0</sup>, and Ag.<sup>0</sup>-coated-Au.<sup>0</sup> nanoparticles. Their TEM and FESEM images demonstrated that they are soft, non-aggregated, well-dispersed, and spherically shaped particles with mean diameters of 13.10 nm and 20.00 nm for CgAgNPs and CgAg<sup>0</sup>-Au<sup>0</sup>NPs, respectively, whereas, particles of CgAuNPs exhibited the same characteristics but had variable shapes including spherical, cylindrical, triangular, pentagonal, and hexagonal with a mean diameter of 29.48 nm. Their mean hydrodynamic sizes (from DLS), core sizes (from TEM), and crystallite sizes (from PXRD) appeared in the range of 4.0–45.5 nm, which follows a trend of crystallite sizes ˂ core sized ˂ hydrodynamic sizes. Besides the crystallite sizes, PXRD analysis exposed their purity and crystallinity with average crystallite diameters (nm) of 4.49 for CgAgNPs, 9.23 for CgAuNPs, and 7.9 for CgAg<sup>0</sup>-Au<sup>0</sup>NPs. These nanoparticles are highly stable as revealed by their zeta potential values which were further supported by their hardness (դ) values obtained from the Tauc plot for the bandgap energies that followed a trend of դ= 2.495 (–29.5 mV) ˃ դ= 2.315 (–27.4 mV) ˃ դ= 1.495 (–13.2 mV) for CgAg<sup>0</sup>-Au<sup>0</sup>NPs, CgAgNPs, and CgAuNPs, respectively. The robust stability preserved their physicochemical behaviour over time and equipped them with promising biological effects. The binding potential of these nanoparticles to C.t.DNA revealed effective interaction with binding constant (K<sub>b</sub>) values of 2.467 × 10<sup>3</sup> (CgAgNPs), 2.438 × 10<sup>3</sup> (CgAuNPs), and 2.199 × 10<sup>3</sup> (CgAg<sup>0</sup>-Au<sup>0</sup>NP), suggesting their usage as antimicrobial agents. Following this, they were investigated for antibacterial activities and the outcomes unveiled strong activity with potent <em>IC</em><sub><em>50</em></sub> of 0.05 mg/ml(50 µg./ml) over <em>Staphylococcus aureus</em> and 0.1 mg/ml(100 µg/ml) over <em>Pseudomonas aeruginosa</em> for CgAgNPs; 0.1 mg/ml(100 µg/ml) over both organisms for CgAuNPs; and 0.05 mg/ml(50 µg/ml) over both organisms for CgAg<sup>0</sup>-Au<sup>0</sup>NPs. Their stability, softness, non-aggregation, and well-dispersed nature equipped them with incredible biological effects which are credited to the synergistic potential contributed by each component.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101432"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.nanoso.2024.101426
Ayushmaan Roy , Mohammad Adnan Raza , Vijayalakshmi Ghosh , Ajazuddin
Colorectal cancer (CRC) is a frequently occurring malignant disease that affects people worldwide, especially those who are 50 years old or older and have a higher chance of developing the disease. Although improvements in diagnostic techniques and early screening have led to a decrease in cancer-related deaths, there remains an urgent want for novel treatment approaches. Scientists are quickly acknowledging the importance of nanoparticles (NPs) in improving the accuracy, effectiveness, and availability of diagnostic and treatments by enhancing the precision, solubility, and accessibility of pharmaceuticals. Nanoparticles (NPs) show potential in reducing medication toxicity and specifically targeting malignant tumors, therefore decreasing adverse side effects. This study comprehensively evaluates the practicality of using various nano products to detect and treat colorectal cancer (CRC). This study adds to the paradigm change in CRC management by conducting a thorough analysis of the potential of NPs. Incorporating cutting-edge nanotechnologies into CRC treatments can bring about significant changes, providing a way to develop individualized and precise therapies. This analysis highlights the need to use new and creative methods to satisfy the ongoing requirement for advanced therapies in light of the worldwide effect of colorectal cancer (CRC). With the increasing need for effective treatments, investigating nanoproducts becomes a new area of study with significant implications for CRC management. This highlights the need for ongoing research and development in this rapidly evolving sector.
{"title":"Diagnostic innovations and therapeutic potential of nanoparticulate delivery for colon cancer","authors":"Ayushmaan Roy , Mohammad Adnan Raza , Vijayalakshmi Ghosh , Ajazuddin","doi":"10.1016/j.nanoso.2024.101426","DOIUrl":"10.1016/j.nanoso.2024.101426","url":null,"abstract":"<div><div>Colorectal cancer (CRC) is a frequently occurring malignant disease that affects people worldwide, especially those who are 50 years old or older and have a higher chance of developing the disease. Although improvements in diagnostic techniques and early screening have led to a decrease in cancer-related deaths, there remains an urgent want for novel treatment approaches. Scientists are quickly acknowledging the importance of nanoparticles (NPs) in improving the accuracy, effectiveness, and availability of diagnostic and treatments by enhancing the precision, solubility, and accessibility of pharmaceuticals. Nanoparticles (NPs) show potential in reducing medication toxicity and specifically targeting malignant tumors, therefore decreasing adverse side effects. This study comprehensively evaluates the practicality of using various nano products to detect and treat colorectal cancer (CRC). This study adds to the paradigm change in CRC management by conducting a thorough analysis of the potential of NPs. Incorporating cutting-edge nanotechnologies into CRC treatments can bring about significant changes, providing a way to develop individualized and precise therapies. This analysis highlights the need to use new and creative methods to satisfy the ongoing requirement for advanced therapies in light of the worldwide effect of colorectal cancer (CRC). With the increasing need for effective treatments, investigating nanoproducts becomes a new area of study with significant implications for CRC management. This highlights the need for ongoing research and development in this rapidly evolving sector.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101426"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.nanoso.2024.101418
M. Kiran , N.S. Leel , P.A. Alvi , B. Dalela , Shalendra Kumar , N. Jakhar , A. Sharma , S. Dalela
The structure and functional properties of materials can be significantly influenced by the synthesis of nanoparticles. This manuscript presents undoped CeO2 and Ag doped CeO2 nanoparticles (NPs) with different concentration of Ag (x = 0.03, 0.05 and 0.07), prepared using a simple coprecipitation route of synthesis. The prepared NPs have been characterized via X-ray diffraction (XRD), UV-Vis NIR spectroscopy, photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and electrochemical analysis. The XRD measurement infers the improvement in the crystalline nature with Ag-doping and crystallite size between 13 and 9 nm. The absorption spectra reflect the red shifting of the absorption peaks along with the narrowing of band gap with rise in the Ag concentration. To ascertain the defects and excitation wavelength, PL measurement has been performed. High color rendering index (CRI) of the prepared samples showed good luminescence with white light emission. The development of oxygen vacancies (Vo) upon Ag doping is further confirmed by XPS measurement. In addition, the XPS measurements revealed the charged oxygen vacancies as well as the valence states of Ce with 3+ and 4+ , Ag with 1+ , and O with 2–. The CV test verified that in 2 M KOH electrolyte solution, the 5 % Ag-doped CeO2 NPs had the maximum specific capacitance (CSP) value of 363.44 F/g at scan rate of 10 mV/s the best cycle stability (retaining 93.90 % after 2100 cycles). It was discovered that the 5 % Ag-doped CeO2 NPs had an energy density of 125.08 Wh/kg and a power density of 652.48 W/kg. An excellent super capacitive performance of Ag doping in CeO2 could be used as a unique electrode material to develop high-efficiency and durable energy storage devices and resulted in the enrichment of electrochemical properties of these nanomaterials. Cyclic voltammetry (CV) results are consistent with electrochemical impedance spectroscopy, indicating good voltammetry and impedance spectroscopy performance of Ag-doped CeO2 NPs. These nano-materials are also better alternatives for solid state electrolyte for fuel cells, UV blockers, photo-catalyst and many other applications.
{"title":"Enhanced electrochemical properties for better stability of supercapacitance and electronic structure characteristics of Ag-doped CeO2 nanoparticles","authors":"M. Kiran , N.S. Leel , P.A. Alvi , B. Dalela , Shalendra Kumar , N. Jakhar , A. Sharma , S. Dalela","doi":"10.1016/j.nanoso.2024.101418","DOIUrl":"10.1016/j.nanoso.2024.101418","url":null,"abstract":"<div><div>The structure and functional properties of materials can be significantly influenced by the synthesis of nanoparticles. This manuscript presents undoped CeO<sub>2</sub> and Ag doped CeO<sub>2</sub> nanoparticles (NPs) with different concentration of Ag (x = 0.03, 0.05 and 0.07), prepared using a simple coprecipitation route of synthesis. The prepared NPs have been characterized via X-ray diffraction (XRD), UV-Vis NIR spectroscopy, photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and electrochemical analysis. The XRD measurement infers the improvement in the crystalline nature with Ag-doping and crystallite size between 13 and 9 nm. The absorption spectra reflect the red shifting of the absorption peaks along with the narrowing of band gap with rise in the Ag concentration. To ascertain the defects and excitation wavelength, PL measurement has been performed. High color rendering index (CRI) of the prepared samples showed good luminescence with white light emission. The development of oxygen vacancies (V<sub>o</sub>) upon Ag doping is further confirmed by XPS measurement. In addition, the XPS measurements revealed the charged oxygen vacancies as well as the valence states of Ce with 3+ and 4+ , Ag with 1+ , and O with 2–. The CV test verified that in 2 M KOH electrolyte solution, the 5 % Ag-doped CeO<sub>2</sub> NPs had the maximum specific capacitance (C<sub>SP</sub>) value of 363.44 F/g at scan rate of 10 mV/s the best cycle stability (retaining 93.90 % after 2100 cycles). It was discovered that the 5 % Ag-doped CeO<sub>2</sub> NPs had an energy density of 125.08 Wh/kg and a power density of 652.48 W/kg. An excellent super capacitive performance of Ag doping in CeO<sub>2</sub> could be used as a unique electrode material to develop high-efficiency and durable energy storage devices and resulted in the enrichment of electrochemical properties of these nanomaterials. Cyclic voltammetry (CV) results are consistent with electrochemical impedance spectroscopy, indicating good voltammetry and impedance spectroscopy performance of Ag-doped CeO<sub>2</sub> NPs. These nano-materials are also better alternatives for solid state electrolyte for fuel cells, UV blockers, photo-catalyst and many other applications.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101418"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Implants that can modify biological signals or environmental factors are now a focal point in the realm of biomedical applications. These groundbreaking devices hold immense potential to transform medical procedures and tools. Integrating 2D nano additives such as graphene, graphene oxide, and Mxene into Polyurethane (PU), due to their bioswitchability, durability, and shape memory capabilities make it an attractive material for bioswitchable implants. Although these materials have immense potential, they still face complications regarding their compatibility with living beings, capacity to bear mechanical stress, and regulated degradation rate. This can be improved by compiling them with biocompatible materials that enhance their properties. Various processing methods are explored for integrating nano additives into PU matrices, like electrospinning, 3D printing, solvent casting and particulate leaching, thermoplastic molding, and melt blending has been encompassed in this article. This review highlights PU-based bioswitchable implants’ advancements in dentistry, bone implants, drug delivery, tissue regeneration, and cancer therapy. Integrating nanomaterials enhances the implants' physical, biological, cytotoxic, and long-term monitoring profiles. The main focus is on employing robotic touch to interact with biological systems and operate implants dynamically. This research reveals that PU-based bioswitchable implants and robotic fingertips might revolutionize regenerative medicine by increasing patient outcomes.
{"title":"Bioswitchable Polyurethane Implants: Enhancing Performance with 2D Nano Additives","authors":"Anushka Grace Binod , Payal Varma , Balasubramanian Kandasubramanian","doi":"10.1016/j.nanoso.2025.101454","DOIUrl":"10.1016/j.nanoso.2025.101454","url":null,"abstract":"<div><div>Implants that can modify biological signals or environmental factors are now a focal point in the realm of biomedical applications. These groundbreaking devices hold immense potential to transform medical procedures and tools. Integrating 2D nano additives such as graphene, graphene oxide, and Mxene into Polyurethane (PU), due to their bioswitchability, durability, and shape memory capabilities make it an attractive material for bioswitchable implants. Although these materials have immense potential, they still face complications regarding their compatibility with living beings, capacity to bear mechanical stress, and regulated degradation rate. This can be improved by compiling them with biocompatible materials that enhance their properties. Various processing methods are explored for integrating nano additives into PU matrices, like electrospinning, 3D printing, solvent casting and particulate leaching, thermoplastic molding, and melt blending has been encompassed in this article. This review highlights PU-based bioswitchable implants’ advancements in dentistry, bone implants, drug delivery, tissue regeneration, and cancer therapy. Integrating nanomaterials enhances the implants' physical, biological, cytotoxic, and long-term monitoring profiles. The main focus is on employing robotic touch to interact with biological systems and operate implants dynamically. This research reveals that PU-based bioswitchable implants and robotic fingertips might revolutionize regenerative medicine by increasing patient outcomes.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101454"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.nanoso.2025.101451
Hanan Alenzi , Mahmood Alhajj , S.K. Ghoshal , Muhammad Safwan , Hana Abdullah Alluhaybi
Repeated studies revealed that various nanostructures with tailored physicochemical properties are highly desirable for biomedical and engineering applications. Hence, this study investigates the systematic synthesis and characterizations of gold/copper nanocomposites (Au-CuNCs) prepared via the pulsed laser ablation in liquid (PLAL) approach. In this process, solid Au and Cu targets were ablated in deionized water (DIW) using a nanosecond pulsed laser at two different wavelengths (1064 nm and 532 nm). The primary objective is to evaluate the impact of laser wavelength variation on the structural, optical, and morphological properties of the resulting NCs. All NCs were analysed to evaluate the effect of varying wavelengths on their fluorescence, absorbance, morphology, and structure. TEM, HRTEM, and STEM images confirmed the nucleation of Au-CuNCs with the corresponding mean diameters of 7.88 ± 3.97 and 6.39 ± 4.07 nm of 1064 and 532 nm, respectively. ATR-IR and XRD analysis affirmed the high purity and strong nanocrystallinity of all specimens, respectively. EDX maps and spectra of the obtained NCs disclosed the distributions and compositions of constituent chemical elements. The lifetime decay analyses of the NCs exhibited an appreciably low fluorescence lifetime of 2.83 µs and 2.74 µs of the donor, ascribed to radiative energy transfer and photon emission. Optical band gap energy of the NCs made at 1064 nm 532 nm corresponded to 3.90 eV and 4.03 eV. It is established that via the change of the ablating laser wavelength, the physical characteristics of these NCs can be tailored, contributing to sustainable growth with diverse applications.
{"title":"Short and long wavelength laser pulse-dependent physicochemical properties of plasmonic metal nanocomposites: A comparative assessment","authors":"Hanan Alenzi , Mahmood Alhajj , S.K. Ghoshal , Muhammad Safwan , Hana Abdullah Alluhaybi","doi":"10.1016/j.nanoso.2025.101451","DOIUrl":"10.1016/j.nanoso.2025.101451","url":null,"abstract":"<div><div>Repeated studies revealed that various nanostructures with tailored physicochemical properties are highly desirable for biomedical and engineering applications. Hence, this study investigates the systematic synthesis and characterizations of gold/copper nanocomposites (Au-CuNCs) prepared via the pulsed laser ablation in liquid (PLAL) approach. In this process, solid Au and Cu targets were ablated in deionized water (DIW) using a nanosecond pulsed laser at two different wavelengths (1064 nm and 532 nm). The primary objective is to evaluate the impact of laser wavelength variation on the structural, optical, and morphological properties of the resulting NCs. All NCs were analysed to evaluate the effect of varying wavelengths on their fluorescence, absorbance, morphology, and structure. TEM, HRTEM, and STEM images confirmed the nucleation of Au-CuNCs with the corresponding mean diameters of 7.88 ± 3.97 and 6.39 ± 4.07 nm of 1064 and 532 nm, respectively. ATR-IR and XRD analysis affirmed the high purity and strong nanocrystallinity of all specimens, respectively. EDX maps and spectra of the obtained NCs disclosed the distributions and compositions of constituent chemical elements. The lifetime decay analyses of the NCs exhibited an appreciably low fluorescence lifetime of 2.83 µs and 2.74 µs of the donor, ascribed to radiative energy transfer and photon emission. Optical band gap energy of the NCs made at 1064 nm 532 nm corresponded to 3.90 eV and 4.03 eV. It is established that via the change of the ablating laser wavelength, the physical characteristics of these NCs can be tailored, contributing to sustainable growth with diverse applications.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101451"},"PeriodicalIF":5.45,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号