US National Estimates of Contemporary Mortality Rates in Patients With Ulcerative Colitis Undergoing Colectomy.

IF 8 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY American Journal of Gastroenterology Pub Date : 2025-02-01 Epub Date: 2024-08-14 DOI:10.14309/ajg.0000000000003031

Newaz Shubidito Ahmed, Satchel Krawchuk, Katherine A Buhler, Virginia Solitano, Vipul Jairath, Abdel Aziz Shaheen, Cynthia H Seow, Kerri L Novak, Richard J M Ingram, Cathy Lu, Paulo G Kotze, Gilaad G Kaplan, Remo Panaccione, Christopher Ma

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Abstract

Introduction: Despite a growing armamentarium of medical therapies for ulcerative colitis, colectomy remains an important therapeutic option. To better inform shared decision-making about surgery, we estimated the contemporary risk of mortality after colectomy.

Methods: Mortality rates were estimated using the National Inpatient Sample (2016-2020). Factors associated with postcolectomy death were evaluated in multivariable regression.

Results: Postcolectomy mortality occurred in 1.2% (95% CI: 0.8%, 1.9%) of hospitalizations. Comorbidity burden, emergent laparotomy, and delays to surgery >5 days after admission were associated with mortality.

Discussion: Colectomy may be associated with mortality; however, this risk is heterogeneous based on patient- and procedural-related factors.

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美国全国接受结肠切除术的溃疡性结肠炎患者的当代死亡率估计。

目的：尽管治疗溃疡性结肠炎（UC）的药物种类越来越多，但结肠切除术仍是一种重要的治疗选择。为了更好地为手术共同决策提供信息，我们估算了结肠切除术后的当代死亡风险：我们使用全国住院患者样本（2016-2020 年）估算了死亡率。通过多变量回归评估了结肠切除术后死亡的相关因素：结果：1.2% [95% CI: 0.8%, 1.9%]的住院患者在结肠切除术后死亡。合并症负担、急诊开腹手术和入院后手术延迟超过5天与死亡率有关：结肠切除术可能与死亡率有关，但这种风险因患者和手术相关因素而异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Gastroenterology 医学-胃肠肝病学

CiteScore

11.40

自引率

5.10%

发文量

458

审稿时长

12 months

期刊介绍： Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.