Case Report: Brucellosis Mimicking Tuberculous Meningitis in a Child.

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH American Journal of Tropical Medicine and Hygiene Pub Date : 2024-08-13 DOI:10.4269/ajtmh.23-0715
Sevgi Aslan Tuncay, Gulsen Akkoc, Seyhan Yilmaz, Burcu Parlak, Pinar Canizci Erdemli, Aylin Dizi Isik, Eda Kepenekli
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Abstract

Neurobrucellosis is rare in children, presenting with a variety of clinical manifestations, including meningitis, meningoencephalitis, cranial neuropathies, and intracranial mass-like lesions. We present a case of a 17-year-old girl admitted to the hospital in Istanbul for headache. Lumbar puncture showed elevated intracranial pressure, monocytic pleocytosis, elevated total protein, and hypoglycorrhachia. Brucella melitensis grew from the cerebrospinal fluid. The patient was treated with doxycycline, rifampin, amikacin, and ceftriaxone and showed persistent sensorineural hearing loss. It is essential to consider brucellosis in the differential diagnosis of infectious neurological disease in areas where the disease is endemic. Serologic tests and cultures are needed for diagnosis, and efforts need to be made to identify the infecting organism to the species level to guide zoonotic source control efforts.

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病例报告:布鲁氏菌病诱发儿童结核性脑膜炎
神经布鲁氏菌病在儿童中非常罕见,临床表现多种多样,包括脑膜炎、脑膜脑炎、颅神经病变和颅内肿块样病变。我们报告了一例因头痛入住伊斯坦布尔医院的 17 岁女孩的病例。腰椎穿刺显示颅内压升高、单核细胞增多、总蛋白升高和出血过少。脑脊液中长出了布鲁氏菌。患者接受了强力霉素、利福平、阿米卡星和头孢曲松治疗,但出现持续性感音神经性听力损失。在布鲁氏菌病流行的地区,神经系统感染性疾病的鉴别诊断中必须考虑布鲁氏菌病。诊断时需要进行血清学检测和培养,并努力确定感染生物的种类,以指导人畜共患传染源控制工作。
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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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