首页 > 最新文献

American Journal of Tropical Medicine and Hygiene最新文献

英文 中文
Calcified Neurocysticercosis: Understanding Dead (Not Necessarily Inactive) Parasites.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0446
Christina M Coyle, Javier A Bustos, Oscar H Del Brutto, Hector H Garcia, Theodore E Nash, Vedantam Rajshekhar

Neurocysticercosis (NCC) is the most common helminthic infection of the human central nervous system (CNS), and a major cause of acquired epilepsy in most of the world. Although outcomes of NCC have been improved by advanced diagnostic tests, antiparasitic drugs, and appropriate anti-inflammatory treatment, little attention has been paid to calcified NCC. Calcification is a common outcome in NCC and carries increased risk for seizures and hippocampal atrophy/sclerosis. The pathophysiological mechanisms leading to calcification instead of complete resolution are basically unknown. Understanding the causes and mechanisms of calcification can lead to improved therapies aimed at reducing the likelihood of residual calcification or the underlying pathological mechanisms, after the resolution of parasitic lesions in the human CNS.

{"title":"Calcified Neurocysticercosis: Understanding Dead (Not Necessarily Inactive) Parasites.","authors":"Christina M Coyle, Javier A Bustos, Oscar H Del Brutto, Hector H Garcia, Theodore E Nash, Vedantam Rajshekhar","doi":"10.4269/ajtmh.24-0446","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0446","url":null,"abstract":"<p><p>Neurocysticercosis (NCC) is the most common helminthic infection of the human central nervous system (CNS), and a major cause of acquired epilepsy in most of the world. Although outcomes of NCC have been improved by advanced diagnostic tests, antiparasitic drugs, and appropriate anti-inflammatory treatment, little attention has been paid to calcified NCC. Calcification is a common outcome in NCC and carries increased risk for seizures and hippocampal atrophy/sclerosis. The pathophysiological mechanisms leading to calcification instead of complete resolution are basically unknown. Understanding the causes and mechanisms of calcification can lead to improved therapies aimed at reducing the likelihood of residual calcification or the underlying pathological mechanisms, after the resolution of parasitic lesions in the human CNS.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combating Child Undernutrition through Community Participation and Action: Reviving Ballabgarh Mixture at Rural Villages of Haryana, India.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0649
Ankit Chandra
{"title":"Combating Child Undernutrition through Community Participation and Action: Reviving Ballabgarh Mixture at Rural Villages of Haryana, India.","authors":"Ankit Chandra","doi":"10.4269/ajtmh.24-0649","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0649","url":null,"abstract":"","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0665
Juliana Pérez-Pérez, John Alexander Pulgarin Diaz, Guillermo Rúa-Uribe, Blas Mola-Yudego, Eric Delmelle, Raúl Rojo, Frank Berninger

Despite extensive vector control programs, dengue remains a significant global health challenge, with outbreaks rising worldwide. Effective dengue control requires reinforcing the surveillance systems and using surveillance data to gain a better understanding of dengue dynamics at both spatial and temporal scales. We studied the effect of socioeconomic and land cover on the presence of dengue hotspots in Medellin (Colombia) from 2010 to 2020 and identified recurrent hotspots during severe epidemic (SE), epidemic (E), and non-epidemic (NE) years. We focused on spatial autocorrelation using global and local indicators of spatial association over 40,814 georeferenced dengue cases. Later, we tested if the spatial units identified as hotspots, recurrent hotspots, and non-hotspots were evenly distributed among socioeconomic strata and land cover categories. During the study period, 50% of the dengue cases were concentrated in 26% of the study area. We identified statistically significant hotspots, some recurring for up to 7 years with their spatial patterns differing between SE, E, and NE years, even though some recurred over time. Recurrent hotspots predominantly occurred in low-medium socioeconomic strata and were absent in the highest strata. Also, they predominated in human-made structures. The interaction between socioeconomic factors, land cover, and potentially, the vector presence seems to explain the spatial variation of dengue epidemics and their recurrent hotspots in Medellin.

{"title":"Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.","authors":"Juliana Pérez-Pérez, John Alexander Pulgarin Diaz, Guillermo Rúa-Uribe, Blas Mola-Yudego, Eric Delmelle, Raúl Rojo, Frank Berninger","doi":"10.4269/ajtmh.24-0665","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0665","url":null,"abstract":"<p><p>Despite extensive vector control programs, dengue remains a significant global health challenge, with outbreaks rising worldwide. Effective dengue control requires reinforcing the surveillance systems and using surveillance data to gain a better understanding of dengue dynamics at both spatial and temporal scales. We studied the effect of socioeconomic and land cover on the presence of dengue hotspots in Medellin (Colombia) from 2010 to 2020 and identified recurrent hotspots during severe epidemic (SE), epidemic (E), and non-epidemic (NE) years. We focused on spatial autocorrelation using global and local indicators of spatial association over 40,814 georeferenced dengue cases. Later, we tested if the spatial units identified as hotspots, recurrent hotspots, and non-hotspots were evenly distributed among socioeconomic strata and land cover categories. During the study period, 50% of the dengue cases were concentrated in 26% of the study area. We identified statistically significant hotspots, some recurring for up to 7 years with their spatial patterns differing between SE, E, and NE years, even though some recurred over time. Recurrent hotspots predominantly occurred in low-medium socioeconomic strata and were absent in the highest strata. Also, they predominated in human-made structures. The interaction between socioeconomic factors, land cover, and potentially, the vector presence seems to explain the spatial variation of dengue epidemics and their recurrent hotspots in Medellin.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Post-Kala-Azar Dermal Leishmaniasis in Sudan: Cases, Ethnic Distribution, and Recovery.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0602
Osama S Osman, Mohamed E Hamid

Post-kala-azar dermal leishmaniasis (PKDL) is a neglected tropical disease that can develop after treatment of leishmaniasis. It causes significant health risks and serves as a reservoir, perpetuating transmission. Current information on PKDL characteristics is crucial for effective disease management and control. This study aimed to describe clinical and epidemiological characteristics of PKDL patients in eastern Sudan. A retrospective cross-sectional study was conducted on suspected PKDL patients (N = 37) at a tertiary hospital in eastern Sudan. Blood samples were tested for anti-rK39 antibodies to confirm the diagnosis of the disease. Demographic, clinical, and epidemiological data of the PKDL patients were gathered and analyzed. Most PKDL cases (69.4%) came from specific locations involving one ethnic group (94.6%), mainly affecting young males (54.1%). A family history of PKDL was noted in only 27.0% of cases; 51.4% developed PKDL within 1 month after visceral leishmaniasis (VL) treatment. Most cases (56.8%) were grade 1 (a low level of parasitic load), predominantly featuring macular (51.4%), papular (18.9%), and nodular (13.5%) lesions. All patients had skin rashes; 91.9% exhibited no fever, and 29.7% reported itching. Lesions appeared within a month after VL treatment, with most patients recovering spontaneously within 3-18 months. PKDL was particularly prevalent in specific regions and ethnic groups, namely the Masaleet and Dago tribes. These findings can enhance PKDL understanding and management in the region.

{"title":"Trends in Post-Kala-Azar Dermal Leishmaniasis in Sudan: Cases, Ethnic Distribution, and Recovery.","authors":"Osama S Osman, Mohamed E Hamid","doi":"10.4269/ajtmh.24-0602","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0602","url":null,"abstract":"<p><p>Post-kala-azar dermal leishmaniasis (PKDL) is a neglected tropical disease that can develop after treatment of leishmaniasis. It causes significant health risks and serves as a reservoir, perpetuating transmission. Current information on PKDL characteristics is crucial for effective disease management and control. This study aimed to describe clinical and epidemiological characteristics of PKDL patients in eastern Sudan. A retrospective cross-sectional study was conducted on suspected PKDL patients (N = 37) at a tertiary hospital in eastern Sudan. Blood samples were tested for anti-rK39 antibodies to confirm the diagnosis of the disease. Demographic, clinical, and epidemiological data of the PKDL patients were gathered and analyzed. Most PKDL cases (69.4%) came from specific locations involving one ethnic group (94.6%), mainly affecting young males (54.1%). A family history of PKDL was noted in only 27.0% of cases; 51.4% developed PKDL within 1 month after visceral leishmaniasis (VL) treatment. Most cases (56.8%) were grade 1 (a low level of parasitic load), predominantly featuring macular (51.4%), papular (18.9%), and nodular (13.5%) lesions. All patients had skin rashes; 91.9% exhibited no fever, and 29.7% reported itching. Lesions appeared within a month after VL treatment, with most patients recovering spontaneously within 3-18 months. PKDL was particularly prevalent in specific regions and ethnic groups, namely the Masaleet and Dago tribes. These findings can enhance PKDL understanding and management in the region.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mark-Release-Recapture of Packed and Shipped Aedes aegypti with Wolbachia: Implications for Conducting Remote Incompatible Insect Technique Programs.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0262
Johanna R Ohm, Amy Lynd, Austin McGowan, Angel Cupid, Vernessa Bellot, James Q Le, Evdoxia Kakani, Josh Livni, Jacob E Crawford, Bradley J White

Male mosquitoes containing the endosymbiont Wolbachia (Wb+) can be used as a tool to suppress wild mosquito populations through a technique termed incompatible insect technique (IIT). IIT programs reduce wild mosquitoes via incompatible matings between released males and wild females to reduce the number of viable offspring produced in the next generation. Successful programs rely on regular release of incompatible males to outcompete wild males for female mates. Past IIT programs have relied on local production of Wb+ males to support regular releases of incompatible males. Here, we evaluated the survival and dispersal of packed and shipped Wb+ Aedes aegypti males in mark-release-recapture studies at a release site in the British Virgin Islands (BVI), separated by over 3,600 miles from the centralized production facility. Released mosquitoes were recaptured using BG-Sentinel 2 traps collected daily for up to 7 days after release. Wb+ male mosquitoes packed and shipped from a centralized production facility performed similarly to males that were locally reared in the BVI in survival, dispersal, and recapture rates. Our results support the conclusion that packing and shipping live Wb+ male mosquitoes does not impact their ability to survive and disperse in release sites and suggests that IIT mosquito control programs can feasibly be conducted nearly anywhere in the world without the need for local mosquito production facilities.

{"title":"Mark-Release-Recapture of Packed and Shipped Aedes aegypti with Wolbachia: Implications for Conducting Remote Incompatible Insect Technique Programs.","authors":"Johanna R Ohm, Amy Lynd, Austin McGowan, Angel Cupid, Vernessa Bellot, James Q Le, Evdoxia Kakani, Josh Livni, Jacob E Crawford, Bradley J White","doi":"10.4269/ajtmh.24-0262","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0262","url":null,"abstract":"<p><p>Male mosquitoes containing the endosymbiont Wolbachia (Wb+) can be used as a tool to suppress wild mosquito populations through a technique termed incompatible insect technique (IIT). IIT programs reduce wild mosquitoes via incompatible matings between released males and wild females to reduce the number of viable offspring produced in the next generation. Successful programs rely on regular release of incompatible males to outcompete wild males for female mates. Past IIT programs have relied on local production of Wb+ males to support regular releases of incompatible males. Here, we evaluated the survival and dispersal of packed and shipped Wb+ Aedes aegypti males in mark-release-recapture studies at a release site in the British Virgin Islands (BVI), separated by over 3,600 miles from the centralized production facility. Released mosquitoes were recaptured using BG-Sentinel 2 traps collected daily for up to 7 days after release. Wb+ male mosquitoes packed and shipped from a centralized production facility performed similarly to males that were locally reared in the BVI in survival, dispersal, and recapture rates. Our results support the conclusion that packing and shipping live Wb+ male mosquitoes does not impact their ability to survive and disperse in release sites and suggests that IIT mosquito control programs can feasibly be conducted nearly anywhere in the world without the need for local mosquito production facilities.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype in Costa Rica.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0633
Vanessa Villalobos-Alfaro, María José Uribe-Calvo, Eugenia Corrales-Aguilar, Tatiana Murillo

Dengue virus produces dengue fever, which can cause severe manifestations. Virus serotype and genotype may impact the epidemiology and severity of the disease. At the Hospital México (Costa Rica), dengue diagnosis and serotyping are performed with molecular tests, but selected samples are sequenced using Illumina technology. In May 2024, we analyzed two dengue-positive samples through genomic sequencing and detected dengue serotype 2, Cosmopolitan genotype. Phylogenetic comparisons revealed that the Costa Rican genomes are closely related to those from Brazil, Peru, and Colombia. Molecular dating estimated that the sequences from Costa Rica diverged in January 2024, suggesting that this genotype may already have been circulating in the country. The emergence of this genotype could impact the severity and epidemiology of dengue in Costa Rica. Therefore, genomic and epidemiological surveillance of dengue cases locally is important to better understand the public health impact of this new genotype in the country.

{"title":"Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype in Costa Rica.","authors":"Vanessa Villalobos-Alfaro, María José Uribe-Calvo, Eugenia Corrales-Aguilar, Tatiana Murillo","doi":"10.4269/ajtmh.24-0633","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0633","url":null,"abstract":"<p><p>Dengue virus produces dengue fever, which can cause severe manifestations. Virus serotype and genotype may impact the epidemiology and severity of the disease. At the Hospital México (Costa Rica), dengue diagnosis and serotyping are performed with molecular tests, but selected samples are sequenced using Illumina technology. In May 2024, we analyzed two dengue-positive samples through genomic sequencing and detected dengue serotype 2, Cosmopolitan genotype. Phylogenetic comparisons revealed that the Costa Rican genomes are closely related to those from Brazil, Peru, and Colombia. Molecular dating estimated that the sequences from Costa Rica diverged in January 2024, suggesting that this genotype may already have been circulating in the country. The emergence of this genotype could impact the severity and epidemiology of dengue in Costa Rica. Therefore, genomic and epidemiological surveillance of dengue cases locally is important to better understand the public health impact of this new genotype in the country.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significant Reduction in Seroprevalence of Antibodies Against Hepatitis A across Thailand, 2024.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0702
Phattharaporn Inma, Pornjarim Nilyanimit, Nasamon Wanlapakorn, Ratchadawan Aeemjinda, Sumeth Korkong, Prangnapitch Wihanthong, Narong Thawinwisan, Pichet Puedkuntod, Watcharanan Tinnaitorn, Montana Foonoi, Pornsawan Meechin, Yong Poovorawan

Hepatitis A virus (HAV) is an RNA virus that causes acute hepatitis and is transmitted via the fecal-oral route. It has historically been highly endemic in Thailand, where most children develop lifelong immunity after infection. Economic development and improved sanitation have reduced HAV transmission, but immunity levels have declined, raising concerns about potential future outbreaks. This study aims to assess the seroprevalence of HAV antibodies in Thailand in 2024, 10 years after the last national survey in 2014, and to evaluate current immunity levels to inform public health strategies. A cross-sectional study was conducted in a population aged 6 months to 80 years across Thailand's geographic regions. A total of 4,312 serum samples were tested for anti-HAV antibodies using the chemiluminescent microparticle immunoassay. The seroprevalence data were compared with findings from previous surveys in 2004 and 2014. The study showed a significant decline in population immunity to HAV, with the age at which 50% of individuals had antibodies increasing from 36 in 2004 to 42 in 2014, and to 47 years in 2024. A majority of the population remained susceptible to HAV, particularly among younger age groups. Thailand has transitioned to low HAV endemicity, with a large proportion of the population lacking immunity. Despite the absence of significant outbreaks in recent decades, the risk of future outbreaks remains, particularly from imported cases. Enhanced surveillance and vaccination strategies are necessary to prevent future HAV transmission and manage public health risks.

甲型肝炎病毒(HAV)是一种 RNA 病毒,可引起急性肝炎,通过粪口途径传播。甲型肝炎历来在泰国高度流行,大多数儿童在感染后会产生终身免疫。经济的发展和卫生条件的改善减少了 HAV 的传播,但免疫水平却有所下降,这引起了人们对未来可能爆发 HAV 的担忧。本研究旨在评估泰国 HAV 抗体血清流行率,即在 2014 年进行上一次全国调查 10 年后的 2024 年,并评估当前的免疫水平,为公共卫生策略提供参考。这项横断面研究在泰国各地区 6 个月至 80 岁的人群中进行。采用化学发光微粒子免疫测定法对4312份血清样本进行了抗HAV抗体检测。血清流行率数据与 2004 年和 2014 年的调查结果进行了比较。研究显示,人群对 HAV 的免疫力明显下降,50% 的人有抗体的年龄从 2004 年的 36 岁上升到 2014 年的 42 岁,到 2024 年将上升到 47 岁。大多数人口仍对艾滋病毒易感,尤其是年轻群体。泰国已过渡到 HAV 低流行国家,大部分人口缺乏免疫力。尽管近几十年来没有发生重大疫情,但未来仍有爆发的风险,特别是来自输入性病例的风险。有必要加强监测和疫苗接种战略,以防止未来的 HAV 传播并管理公共卫生风险。
{"title":"Significant Reduction in Seroprevalence of Antibodies Against Hepatitis A across Thailand, 2024.","authors":"Phattharaporn Inma, Pornjarim Nilyanimit, Nasamon Wanlapakorn, Ratchadawan Aeemjinda, Sumeth Korkong, Prangnapitch Wihanthong, Narong Thawinwisan, Pichet Puedkuntod, Watcharanan Tinnaitorn, Montana Foonoi, Pornsawan Meechin, Yong Poovorawan","doi":"10.4269/ajtmh.24-0702","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0702","url":null,"abstract":"<p><p>Hepatitis A virus (HAV) is an RNA virus that causes acute hepatitis and is transmitted via the fecal-oral route. It has historically been highly endemic in Thailand, where most children develop lifelong immunity after infection. Economic development and improved sanitation have reduced HAV transmission, but immunity levels have declined, raising concerns about potential future outbreaks. This study aims to assess the seroprevalence of HAV antibodies in Thailand in 2024, 10 years after the last national survey in 2014, and to evaluate current immunity levels to inform public health strategies. A cross-sectional study was conducted in a population aged 6 months to 80 years across Thailand's geographic regions. A total of 4,312 serum samples were tested for anti-HAV antibodies using the chemiluminescent microparticle immunoassay. The seroprevalence data were compared with findings from previous surveys in 2004 and 2014. The study showed a significant decline in population immunity to HAV, with the age at which 50% of individuals had antibodies increasing from 36 in 2004 to 42 in 2014, and to 47 years in 2024. A majority of the population remained susceptible to HAV, particularly among younger age groups. Thailand has transitioned to low HAV endemicity, with a large proportion of the population lacking immunity. Despite the absence of significant outbreaks in recent decades, the risk of future outbreaks remains, particularly from imported cases. Enhanced surveillance and vaccination strategies are necessary to prevent future HAV transmission and manage public health risks.</p>","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
US Public Health and Biomedical Research Institutions Help Keep the World Safe and Deserve Continued Strong Support.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-13 DOI: 10.4269/ajtmh.25-0156
Philip J Rosenthal, Davidson H Hamer, Daniel G Bausch, Jamie Bay Nishi, David A Fidock
{"title":"US Public Health and Biomedical Research Institutions Help Keep the World Safe and Deserve Continued Strong Support.","authors":"Philip J Rosenthal, Davidson H Hamer, Daniel G Bausch, Jamie Bay Nishi, David A Fidock","doi":"10.4269/ajtmh.25-0156","DOIUrl":"https://doi.org/10.4269/ajtmh.25-0156","url":null,"abstract":"","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When Combatting Ebola and other Outbreak-Prone Pathogens, Global Health is American's Health.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-13 DOI: 10.4269/ajtmh.25-0153
Daniel G Bausch, David Heymann
{"title":"When Combatting Ebola and other Outbreak-Prone Pathogens, Global Health is American's Health.","authors":"Daniel G Bausch, David Heymann","doi":"10.4269/ajtmh.25-0153","DOIUrl":"https://doi.org/10.4269/ajtmh.25-0153","url":null,"abstract":"","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial Papulopustular Eruption in an Adult: An Underreported Complication of Miliaria.
IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-03-13 DOI: 10.4269/ajtmh.24-0680
Akshay Meena, Arun Somasundaram, Sivaranjini Ramassamy
{"title":"Facial Papulopustular Eruption in an Adult: An Underreported Complication of Miliaria.","authors":"Akshay Meena, Arun Somasundaram, Sivaranjini Ramassamy","doi":"10.4269/ajtmh.24-0680","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0680","url":null,"abstract":"","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
American Journal of Tropical Medicine and Hygiene
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1