Analysis of the efficacy of angiojet percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis versus catheter-directed thrombolysis alone in the treatment of subacute iliofemoral deep venous thrombosis in elderly patients.

Luyi Cong, Lihua Huang, Benfang Fan, Xin Hong, Lingyu Ma, Tianan Huang
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Abstract

Purpose: To analysis the clinical efficacy of Angiojet percutaneous mechanical thrombectomy (PMT) combined with Catheter-Directed Thrombolysis (CDT) compared to CDT in treatment of subacute iliofemoral deep venous thrombosis (IFDVT) in elderly patients.

Methods: A retrospective analysis of the clinical data of 117 elderly patients hospitalized for subacute IFDVT was conducted. The patients'basic perioperative data and 2-years follow-up data were compared.

Results: Group A (PMT + CDT) had a more patients reaching Grade III thrombus clearance, and a lower thrombolysis time, dosage of thrombolytic drugs, hospital stay, and bleeding incidence compared to Group B (CDT). There was a statistically significant difference in the occurrence rate of severe PTS within 2 years (p < 0.05).

Conclusion: In treating elderly patients with subacute IFDVT, PMT + CDT effectively reduces the thrombus burden and the dosage of thrombolytic drugs, shortens the hospital stay, and importantly, reduces the occurrence rate of severe PTS within 2 years.

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在治疗老年患者亚急性髂股深静脉血栓时,分析血管喷射经皮机械血栓切除术联合导管引导溶栓与单纯导管引导溶栓的疗效。
目的:分析Angiojet经皮机械取栓术(PMT)联合导管引导溶栓术(CDT)治疗老年患者亚急性髂股深静脉血栓(IFDVT)的临床疗效:对117名因亚急性髂股深静脉血栓形成住院的老年患者的临床数据进行了回顾性分析。结果:A 组(PMT + CDT)和 B 组(PMT + CDT)的患者在术后 2 年的随访中均获得了良好的治疗效果:结果:与 B 组(CDT)相比,A 组(PMT + CDT)达到 III 级血栓清除率的患者更多,溶栓时间、溶栓药物用量、住院时间和出血发生率更低。2年内严重PTS的发生率差异有统计学意义(P<0.05):结论:在治疗亚急性 IFDVT 老年患者时,PMT + CDT 可有效减少血栓负荷和溶栓药物用量,缩短住院时间,更重要的是,可降低 2 年内严重 PTS 的发生率。
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