Primary Cutaneous Spindle Cell B-Cell Follicle Center Lymphoma Presenting as Long-Standing Plaque of Cicatricial Alopecia: A Case Report With a Comprehensive Review of the Literature.
Gianmarco D Bigotto, Antonio Podo Brunetti, Stefania Guida, Giorgio Stabile, Nathalie Rizzo, Franco Rongioletti
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引用次数: 0
Abstract
Abstract: Primary cutaneous spindle B-cell lymphoma is an uncommon subtype of cutaneous lymphoma characterized by a distinct spindled cytology of neoplastic B cells. Despite sharing clinical, histopathological, and phenotypical similarities with primary cutaneous follicle center lymphoma, an indolent form of B-cell lymphoma, it also exhibits certain features akin to primary cutaneous diffuse large B-cell lymphoma. Notably, in rare instances, a more aggressive clinical course has been observed. This report details a rare case of primary cutaneous spindle cell B-cell follicle center lymphoma, manifested as a prolonged solitary plaque of cicatricial alopecia. In addition, we provide a comprehensive review of existing cases documented in the literature.
摘要：原发性皮肤纺锤形B细胞淋巴瘤是一种不常见的皮肤淋巴瘤亚型，其特点是肿瘤性B细胞呈明显的纺锤形细胞学。尽管在临床、组织病理学和表型上与原发性皮肤滤泡中心淋巴瘤（B细胞淋巴瘤的一种惰性形式）相似，但它也表现出与原发性皮肤弥漫大B细胞淋巴瘤相似的某些特征。值得注意的是，在极少数情况下，患者的临床病程更具侵袭性。本报告详细介绍了一例罕见的原发性皮肤纺锤形细胞 B 细胞滤泡中心淋巴瘤，表现为长期单发的卡他性脱发斑。此外，我们还对文献中记载的现有病例进行了全面回顾。
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