Primary Cutaneous Spindle Cell B-Cell Follicle Center Lymphoma Presenting as Long-Standing Plaque of Cicatricial Alopecia: A Case Report With a Comprehensive Review of the Literature.

IF 1.1 4区医学 Q4 DERMATOLOGY American Journal of Dermatopathology Pub Date : 2024-12-01 Epub Date: 2024-08-14 DOI:10.1097/DAD.0000000000002752

Gianmarco D Bigotto, Antonio Podo Brunetti, Stefania Guida, Giorgio Stabile, Nathalie Rizzo, Franco Rongioletti

引用次数: 0

Abstract

Abstract: Primary cutaneous spindle B-cell lymphoma is an uncommon subtype of cutaneous lymphoma characterized by a distinct spindled cytology of neoplastic B cells. Despite sharing clinical, histopathological, and phenotypical similarities with primary cutaneous follicle center lymphoma, an indolent form of B-cell lymphoma, it also exhibits certain features akin to primary cutaneous diffuse large B-cell lymphoma. Notably, in rare instances, a more aggressive clinical course has been observed. This report details a rare case of primary cutaneous spindle cell B-cell follicle center lymphoma, manifested as a prolonged solitary plaque of cicatricial alopecia. In addition, we provide a comprehensive review of existing cases documented in the literature.

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原发性皮肤纺锤形细胞 B 细胞滤泡中心淋巴瘤表现为长片状角化性脱发：病例报告与文献综述。

摘要：原发性皮肤纺锤形B细胞淋巴瘤是一种不常见的皮肤淋巴瘤亚型，其特点是肿瘤性B细胞呈明显的纺锤形细胞学。尽管在临床、组织病理学和表型上与原发性皮肤滤泡中心淋巴瘤（B细胞淋巴瘤的一种惰性形式）相似，但它也表现出与原发性皮肤弥漫大B细胞淋巴瘤相似的某些特征。值得注意的是，在极少数情况下，患者的临床病程更具侵袭性。本报告详细介绍了一例罕见的原发性皮肤纺锤形细胞 B 细胞滤泡中心淋巴瘤，表现为长期单发的卡他性脱发斑。此外，我们还对文献中记载的现有病例进行了全面回顾。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Dermatopathology 医学-皮肤病学

CiteScore

1.80

自引率

9.10%

发文量

453

审稿时长

3 months

期刊介绍： The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians

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