Heterogeneity in experiences of vitamin D deficiency in an early to mid-19th century population from Montreal, Quebec

IF 1.3 3区 地球科学 Q3 PALEONTOLOGY International Journal of Paleopathology Pub Date : 2024-08-14 DOI:10.1016/j.ijpp.2024.07.003
Rose-Ann Bigué , Isabelle Ribot , Megan B. Brickley , Bonnie Kahlon , Charlotte A. Roberts
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Abstract

Objective

To use the prevalence of prenatal/infancy interglobular dentine (IGD) as a proxy for suboptimal vitamin D status and explore its link to mortality, biological sex, cultural behaviours and environmental factors during the end of the pre-industrial/ beginning of the industrial period.

Materials

50 skeletons from the St. Antoine cemetery (1799–1854), Montreal, Quebec with a well-preserved first mandibular molar.

Methods

Thin sections were prepared for histological examination of IGD in crown dentine.

Results

IGD prevalence was 74 % (37/50) and not significantly correlated statistically to sex and age-at-death. Most IGD occurred at birth and up to 3 years-old, six individuals were affected in utero, 54 % of the sample (27/50) presented longstanding IGD and six individuals displayed multiple IGD episodes.

Conclusions

Prenatal IGD episodes revealed suboptimal maternal vitamin D levels, which, alongside a high frequency of IGD episodes around birth/from birth until a certain age, suggest cultural influences. Multiple and longstanding IGD episodes might also reflect suboptimal seasonal vitamin D attainment.

Significance

This study provides in-depth data on IGD within a relatively large archaeological North American sample, proving relevant to epidemiological studies on suboptimal vitamin status in 19th century Montreal.

Limitations

The total number of IGD episodes is underestimated due to methodological biases; first-generation migrants in this study could not be identified and excluded from the sample.

Suggestions for further research

Use of a larger sample with a wider age-at-death range; further research on infants and children to investigate links between growth and lesion formation and visibility.

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魁北克蒙特利尔 19 世纪早期至中期人口维生素 D 缺乏经历的异质性
目的利用产前/婴儿期球间牙本质(IGD)的患病率作为维生素 D 不足状态的替代指标,并探讨其与前工业时代末期/工业时代初期的死亡率、生物性别、文化行为和环境因素之间的联系。方法制备薄切片,对牙冠牙本质中的 IGD 进行组织学检查。结果IGD 患病率为 74%(37/50),与性别和死亡年龄无明显统计学关联。大多数 IGD 发生在出生时和 3 岁之前,6 人在子宫内受到影响,54% 的样本(27/50)出现长期 IGD,6 人出现多次 IGD。这项研究提供了一个相对较大的北美考古样本中有关IGD的深入数据,证明与19世纪蒙特利尔维生素不足的流行病学研究相关。局限性由于方法上的偏差,IGD发病总数被低估;本研究中的第一代移民无法被识别并排除在样本之外。
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来源期刊
CiteScore
2.90
自引率
25.00%
发文量
43
期刊介绍: Paleopathology is the study and application of methods and techniques for investigating diseases and related conditions from skeletal and soft tissue remains. The International Journal of Paleopathology (IJPP) will publish original and significant articles on human and animal (including hominids) disease, based upon the study of physical remains, including osseous, dental, and preserved soft tissues at a range of methodological levels, from direct observation to molecular, chemical, histological and radiographic analysis. Discussion of ways in which these methods can be applied to the reconstruction of health, disease and life histories in the past is central to the discipline, so the journal would also encourage papers covering interpretive and theoretical issues, and those that place the study of disease at the centre of a bioarchaeological or biocultural approach. Papers dealing with historical evidence relating to disease in the past (rather than history of medicine) will also be published. The journal will also accept significant studies that applied previously developed techniques to new materials, setting the research in the context of current debates on past human and animal health.
期刊最新文献
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