Identification of 43 novel HLA alleles by PacBio single molecule real-time sequencing in haematopoietic cell donors

IF 5.9 4区 医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-08-15 DOI:10.1111/tan.15645
Albert J. E. French, Jonathan A. M. Lucas, Michael A. Cooper, Steven G. E. Marsh, Neema P. Mayor
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Abstract

A total of 43 novel HLA alleles detected in haematopoietic cell donors using single molecule real-time DNA sequencing.

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通过 PacBio 单分子实时测序鉴定造血细胞供体中的 43 个新型 HLA 等位基因。
利用单分子实时 DNA 测序技术,在造血细胞供体中检测到 43 个新型 HLA 等位基因。
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来源期刊
HLA
HLA Immunology and Microbiology-Immunology
CiteScore
3.00
自引率
28.80%
发文量
368
期刊介绍: HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
期刊最新文献
Characterisation of the HLA-DQ alpha eplet 52SK targeting the DQA1*01 alleles family. Characterisation of the novel HLA-C*01:262 allele by sequencing-based typing. Detection of the HLA-B*40:78 allele in a Taiwanese individual. Identification of three new HLA-A intronic variants by next-generation sequencing. Analysis of KIR and HLA Polymorphism in Chinese Individuals With COVID-19.
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