{"title":"A case of t-cell lymphoblastic lymphoma characterized by pleural effusion combined with pericardial effusion.","authors":"Jiaqing Hu Mengmeng Wang, Jinlong Song","doi":"10.1684/abc.2024.1897","DOIUrl":null,"url":null,"abstract":"<p><p>This case underscores the pivotal role of early cytological examination of bodily fluids in the preliminary detection of lymphoma, a conclusion reinforced by subsequent pathological findings and refined through immunohistochemical characterization. A morphological analysis of pleural effusion cells was conducted in a 25-year-old male presenting initially with concurrent pleural and pericardial effusions. Initial morphological assessment of effusion specimens indicated the likelihood of a lymphoproliferative disorder. Subsequent detailed pathological and immunohistochemical investigations confirmed this suspicion, culminating in a definitive diagnosis of T-cell lymphoblastic lymphoma (T-LBL). The case emphasizes the necessity of employing a comprehensive and synergistic diagnostic approach, facilitating prompt and accurate diagnosis and subtyping of lymphoma.</p>","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 3","pages":"351-355"},"PeriodicalIF":0.0000,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de biologie clinique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1684/abc.2024.1897","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This case underscores the pivotal role of early cytological examination of bodily fluids in the preliminary detection of lymphoma, a conclusion reinforced by subsequent pathological findings and refined through immunohistochemical characterization. A morphological analysis of pleural effusion cells was conducted in a 25-year-old male presenting initially with concurrent pleural and pericardial effusions. Initial morphological assessment of effusion specimens indicated the likelihood of a lymphoproliferative disorder. Subsequent detailed pathological and immunohistochemical investigations confirmed this suspicion, culminating in a definitive diagnosis of T-cell lymphoblastic lymphoma (T-LBL). The case emphasizes the necessity of employing a comprehensive and synergistic diagnostic approach, facilitating prompt and accurate diagnosis and subtyping of lymphoma.
本病例强调了早期体液细胞学检查在初步检测淋巴瘤中的关键作用,随后的病理检查结果和免疫组化鉴定进一步完善了这一结论。一名 25 岁的男性患者最初并发胸腔积液和心包积液,我们对其胸腔积液细胞进行了形态学分析。对积液标本进行的初步形态学评估显示,患者可能患有淋巴增生性疾病。随后进行的详细病理和免疫组化检查证实了这一怀疑,最终确诊为 T 细胞淋巴细胞淋巴瘤(T-LBL)。该病例强调了采用综合、协同诊断方法的必要性,有助于对淋巴瘤进行及时、准确的诊断和亚型鉴定。