Alkaloids from the seeds of Peganum harmala and their chemotaxonomic significance

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-14 DOI:10.1016/j.bse.2024.104884
Xiaojun Li , Xue Zhao , Zhe Liu , Yifan Xia , Yansong Li , Hongjing Dong , Lei Fang
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Abstract

A phytochemical study on the seeds of Peganum harmala led to the separation of 22 alkaloids, including quinazoline alkaloids (110), β-carboline alkaloids (1118), and others alkaloids (1922). Their structures were identified by comprehensive spectroscopic analysis and comparison with literature data. Compounds 14 and 2022 were first isolated from Zygophyllaceae family. Compounds 8 and 15 were firstly discovered as natural products. Moreover, the chemotaxonomic significance of the isolated alkaloids is discussed.

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鹅掌楸种子中的生物碱及其化学分类学意义
通过对 Peganum harmala 种子进行植物化学研究,分离出 22 种生物碱,包括喹唑啉类生物碱(1-10)、β-咔啉类生物碱(11-18)和其他生物碱(19-22)。通过全面的光谱分析和与文献数据的比较,确定了它们的结构。化合物 14 和 20-22 首次从茜草科植物中分离出来。化合物 8 和 15 是首次发现的天然产物。此外,还讨论了所分离生物碱的化学分类学意义。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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