Azul de metileno en intoxicación por cianuro: reporte de caso en paciente con infarto cerebeloso secundario

Abstract

Mortality rates from cyanide poisoning are significantly high due to the devastating effects that this chemical substance can trigger in the body, quickly compromising vital functions. Currently, within the treatment strategies, circulatory and ventilatory support stands out, along with the administration of specific antidotes, which are difficult to access and are not usually available in most hospitals.

Although methylene blue has long been considered an option to counteract the effects of cyanide poisoning, research on its mechanisms of action and effectiveness has been limited for decades, leaving aside its protective effects and properties. unique redox in mitochondrial complexes and the Krebs cycle. A clinical case is presented of a patient with acute potassium cyanide poisoning who responded to antidotal treatment with methylene blue; However, she developed a cerebellar stroke as a consequence of the poisoning, despite having no apparent clinical manifestations.