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Manejo rápido y escalonado en la tormenta arrítmica: reporte de un caso 心律失常风暴中的快速和分步管理:一份病例报告
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.04.001
Alvaro Andrés Montenegro Apraez , Marcela Rivera Portilla , Alejandro Bejarano Zuleta , Eduardo Echeverry , Juan Pablo Garaicoa Garzon
Arrhythmic storm is usually defined as the presentation of 3 or more episodes of ventricular arrhythmias within 24 hours. It is widely accepted that this entity is a medical emergency due to the potential for adverse events such as death in up to 54% of cases, probably because the reduction in cardiac chamber filling time significantly reduces cardiac output, leading to cardiogenic shock, multiple organ failure, and death.
The present case describes a patient with arrhythmic storm secondary to viral myocarditis, due to the recurrence of arrhythmic events despite initial management with antiarrhythmic drugs required a stepwise therapeutic approach guided by a multidisciplinary team and early use of extracorporeal membrane oxygenation (ECMO), which allowed maintaining adequate systemic perfusion while implementing therapeutic measures to control arrhythmic events; The patient was discharged early at 14 days, with no recurrence of arrhythmic events. At 6 months outpatient follow-up, the patient did not require cardiac transplantation, with no recurrence of arrhythmic events, with adequate NYHA functional class I and no left ventricular systolic dysfunction; clinical outcomes are attributed to timely decision making, guided by a multidisciplinary team and early use of early mechanical circulatory support, preventing hypoperfusion, multiple organ failure, and death.
心律失常风暴通常是指在 24 小时内出现 3 次或更多次室性心律失常。人们普遍认为心律失常风暴是一种医疗急症,因为它有可能导致不良事件,例如高达 54% 的病例会导致死亡,这可能是因为心腔充盈时间缩短会显著降低心输出量,从而导致心源性休克、多器官功能衰竭和死亡。本病例描述的是一名继发于病毒性心肌炎的心律失常风暴患者,尽管最初使用了抗心律失常药物,但由于心律失常事件的复发,需要在多学科团队的指导下采取逐步治疗的方法,并尽早使用体外膜肺氧合(ECMO),从而在实施治疗措施控制心律失常事件的同时维持足够的全身灌注。在 6 个月的门诊随访中,患者不需要心脏移植,心律失常事件没有复发,NYHA 功能分级达到 I 级,没有左心室收缩功能障碍;临床结果归功于多学科团队指导下的及时决策和早期使用早期机械循环支持,避免了低灌注、多器官衰竭和死亡。
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引用次数: 0
Presión inspiratoria máxima y presión espiratoria máxima en pacientes de 2 unidades de Cuidados Intensivos en Antioquia, Colombia 哥伦比亚安蒂奥基亚省两家重症监护室病人的吸气峰压和呼气峰压。
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.07.001
Mónica Alejandra Mondragón Barrera, Natalia Tabares Echeverri, Susana María Álvarez Montoya, Nicolás Eugenio Gómez Suárez

Background

Muscle weakness is a common problem in the Intensive Care Unit (ICU), which becomes more critical when it affects the respiratory muscles, as they are essential for maintaining proper ventilation. To assess respiratory muscle strength, measurements of Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) are used, with values related to age, sex, anthropometric measures (height, weight, body mass index), presence of diseases, their chronicity, functionality, among various aspects. In Colombia, the results of measurements in a healthy population differ from those found in North America and European countries, suggesting that there may also be differences in populations with morbidity, such as in the intensive care setting.

Objective

To describe MIP and MEP values based on some sociodemographic, anthropometric, functional, and clinical characteristics in patients from 2 ICUs in Antioquia, Colombia.

Methods

Observational, descriptive study with an analytical intention, cross-sectional design. MIP and MEP were measured, and sociodemographic, anthropometric, functional, clinical, and smoking habit variables were obtained in patients from 2 ICUs in Antioquia.

Results

43 people participated, with most showing muscle weakness compared to the normal limit value. Correlation was found between MIP/MEP and age, sex, height, smoking habit, underlying respiratory disease, having received mechanical ventilation, and handgrip strength weakness.

Conclusions

Values in the studied population allow for a more objective functional assessment and individualized approach.
背景肌肉无力是重症监护病房(ICU)中的一个常见问题,当它影响到呼吸肌时就变得更加严重,因为呼吸肌是维持正常通气的关键。为了评估呼吸肌的力量,需要测量最大吸气压力(MIP)和最大呼气压力(MEP),其数值与年龄、性别、人体测量指标(身高、体重、体重指数)、是否患有疾病、疾病的慢性程度、功能等多方面有关。在哥伦比亚,健康人群的测量结果与北美和欧洲国家的测量结果不同,这表明在发病人群(如重症监护环境)中也可能存在差异。 Objective To describe MIP and MEP values based on some sociodemographic, anthropometric, functional, and clinical characteristics in patients from 2 ICU from Antioquia, Colombia.方法:观察性、描述性研究,分析意图,横断面设计。对安蒂奥基亚省两家重症监护室的患者进行了 MIP 和 MEP 测量,并获得了社会人口学、人体测量、功能、临床和吸烟习惯等变量。研究发现,MIP/MEP 与年龄、性别、身高、吸烟习惯、潜在呼吸系统疾病、接受过机械通气和手握力弱之间存在相关性。
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引用次数: 0
Síndrome de distrés respiratorio agudo por Plasmodium vivax con coinfección de tuberculosis pulmonar en época de pandemia por covid-19. Reporte de caso Covid-19大流行期间合并肺结核感染的间日疟原虫急性呼吸窘迫综合征。病例报告
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.05.004
Ronald Medina , Daniel Molano , Andrés Villa , Cristian Duran , Víctor Gerardino , Said Sánchez
Adult respiratory distress syndrome is a common cause of admission to the intensive care unit, which has been related to high morbidity, mortality and costs. Malaria is a disease mainly caused by Plasmodium falciparum infection and occasionally by Plasmodium vivax. We report the case of a 53-year-old patient who presents with acute respiratory distress syndrome due to Plasmodium vivax and coinfection with Mycobacterium tuberculosis. The diagnosis was made by microbiological and molecular studies respectively. From a clinical perspective, this case represents a diagnostic challenge since it occurs during the SARS CoV-2/covid-19 virus pandemic, being this the main an etiology of adult respiratory distress syndrome during the period of time when our case presented, leaving the microorganisms described in our patient to the minority of causes of adult respiratory distress syndrome.
成人呼吸窘迫综合征是重症监护病房的常见病因,与高发病率、高死亡率和高成本有关。疟疾是一种主要由恶性疟原虫感染引起的疾病,偶尔也会由间日疟原虫感染引起。我们报告了一例 53 岁患者的病例,该患者因间日疟原虫并发结核分枝杆菌感染而出现急性呼吸窘迫综合征。诊断分别是通过微生物学和分子研究得出的。从临床角度来看,本病例是一个诊断难题,因为它发生在非典 CoV-2/covid-19 病毒大流行期间,而这是本病例发病期间成人呼吸窘迫综合征的主要病因,因此本病例中描述的微生物只占成人呼吸窘迫综合征病因的少数。
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引用次数: 0
Correlación del índice resistivo renal y presión de perfusión renal con la severidad de la lesión renal aguda 肾阻力指数和肾灌注压与急性肾损伤严重程度的相关性
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.04.002
Felipe Hernández Silvano, Edgar Bravo Santibañez, Carlos Jiménez Correa, Luis Pedro González Carrillo

Background

Acute kidney injury is a frequent complication in the intensive care unit (ICU) leading to prolonged stay and increased mortality; severity staging requires markers such as creatinine which is late and with multiple factors that bias its measurement and interpretation. Renal ultrasound has increased its use, mainly the resistive index, in addition, the evaluation of renal perfusion in post-surgical patients has been described, however, its relationship with severity in acute kidney injury has not been demonstrated.

Objective

To establish the correlation of the resistive index and renal perfusion pressure with the severity of acute kidney injury in the Intensive Care Unit.

Material and methods

Cross-sectional study in the Intensive Care Unit; patients with acute kidney injury were included and severity was staged according to KDIGO criteria, and renal vascular ultrasonographic measurements were obtained. Statistical analysis was with Kendal's Tau-b test and linear regression analysis.

Results

Final population of 81 patients, the variable that correlated with severity was renal perfusion pressure (r = 0.62, p  0.001) and diastolic velocity (r = 0.30, p = 0.007), however, the resistive index had no correlation (r = 0.135, p = 0.314). Similarly, renal perfusion pressure correlated with changes in creatinine (r = −0.554), BUN (r = −0.480) and bicarbonate (r = 0.331).

Conclusion

No statistically significant results were found in relation to the resistive index, however, we found that the decrease in renal perfusion pressure correlates with greater severity of acute kidney injury in the intensive care unit.
背景急性肾损伤是重症监护病房(ICU)经常发生的并发症,会导致住院时间延长和死亡率升高;严重程度分期需要肌酐等指标,但肌酐的测量和解释较晚,且存在多种偏差因素。肾脏超声(主要是阻力指数)的应用日益广泛,此外,手术后患者的肾脏灌注评估也已得到描述,但其与急性肾损伤严重程度的关系尚未得到证实。材料和方法在重症监护室进行横断面研究;纳入急性肾损伤患者,根据 KDIGO 标准对严重程度进行分期,并获得肾血管超声测量结果。结果81名患者中,与严重程度相关的变量是肾灌注压(r = 0.62,p ≤ 0.001)和舒张速度(r = 0.30,p = 0.007),但阻力指数没有相关性(r = 0.135,p = 0.314)。同样,肾灌注压也与肌酐(r = -0.554)、BUN(r = -0.480)和碳酸氢盐(r = 0.331)的变化相关。
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引用次数: 0
Ecografía en dengue: 10 hallazgos claves 登革热超声波:10 项主要发现
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.05.011
Juan Diego Galindo Dávila , Derly Mileidy Gomez Sandoval , Iván José Ardila Gómez , Doris Martha Salgado García
Dengue virus infection is a public health problem, especially in tropical and subtropical countries like Colombia. Vascular leakage is the central component in the pathophysiology of severe dengue and can be assessed through ultrasound. As a non-invasive method, it can be used as a tool for both diagnosis and clinical stratification, providing timely management and avoiding complications. The aim of this review is to describe key ultrasonographic points in patients with dengue exhibiting warning signs and severe dengue, with a focus on the application of the Point-of-Care Ultrasound (POCUS) strategy. Among the most common findings reported in the literature for dengue patients are thickening of the vesicular wall, pleural effusion, ascites, and pericardial effusion. The integration of POCUS training into routine clinical practice for dengue has the potential to reduce both mortality rates and healthcare costs.
登革热病毒感染是一个公共卫生问题,尤其是在哥伦比亚等热带和亚热带国家。血管渗漏是重症登革热病理生理学的核心组成部分,可通过超声波进行评估。作为一种非侵入性方法,它可作为诊断和临床分层的工具,提供及时的管理并避免并发症。本综述旨在描述登革热患者出现预警征兆和重症登革热时的超声波检查要点,重点是护理点超声波检查(POCUS)策略的应用。文献报道登革热患者最常见的检查结果包括水泡壁增厚、胸腔积液、腹水和心包积液。将 POCUS 培训纳入登革热常规临床实践有可能降低死亡率和医疗成本。
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引用次数: 0
Post-COVID-19 syndrome: When an acute infection causes a chronic illness 后COVID-19综合征:急性感染导致慢性疾病
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.05.001
Olga Helena Hernández Ortiz , Andrés Felipe Naranjo Ramírez , Andrea Sierra Ramírez , Mariana Restrepo Arias , Natalia Betancourt Rodriguez , Francisco José Molina Saldarriaga , Fabian A. Jaimes B. , Jorge E. Osorio , Juan Pablo Hernández Ortiz
We are currently contending with a significant consequence of the SARS-CoV-2 virus pandemic, termed post-COVID syndrome, which has escalated into another global crisis. Conservative estimates suggest that at least 76 million individuals worldwide are grappling with this condition, based on a projected 10% incidence rate among those previously infected. Daily, the tally of cases associated with this syndrome continues to mount. The emergence of long COVID has spurred intensified research endeavors, yet the current volume of ongoing studies falls short, and patient prognosis remains largely unchanged. Consequently, there is an urgent need for enhanced research methodologies to tackle this emerging condition effectively and to mount a robust response to the crisis. Management of post-COVID syndrome primarily revolves around symptomatic relief and rehabilitation strategies aimed at ameliorating the most prevalent symptoms that profoundly impact patients’ quality of life, such as fatigue, dyspnea, and loss of taste and smell. Despite sustained investigative efforts, specific treatments, including steroid therapies, have thus far failed to yield clinically significant outcomes. In this review, we delve into the multifaceted nature of post-COVID syndrome, exploring its impact, current management strategies, and the imperative for advancing research to better understand and address this pressing global health challenge.
目前,我们正在应对 SARS-CoV-2 病毒大流行的一个重要后果,即后 COVID 综合症,它已升级为另一场全球危机。据保守估计,全球至少有 7,600 万人正在与这种病症作斗争,而以前感染过这种病毒的人的发病率预计为 10%。每天,与这种综合症相关的病例都在不断增加。长期 COVID 的出现促进了研究工作的加强,但目前正在进行的研究数量不足,患者的预后仍基本未变。因此,亟需加强研究方法,以有效解决这一新兴病症,并对危机做出强有力的回应。后 COVID 综合征的治疗主要围绕症状缓解和康复策略,旨在改善最普遍的症状,如疲劳、呼吸困难、味觉和嗅觉丧失等,这些症状严重影响患者的生活质量。尽管开展了持续的研究工作,但包括类固醇疗法在内的特定治疗方法至今仍未能取得显著的临床疗效。在这篇综述中,我们深入探讨了后 COVID 综合征的多面性,探讨了它的影响、当前的管理策略以及推进研究以更好地理解和应对这一紧迫的全球健康挑战的必要性。
{"title":"Post-COVID-19 syndrome: When an acute infection causes a chronic illness","authors":"Olga Helena Hernández Ortiz ,&nbsp;Andrés Felipe Naranjo Ramírez ,&nbsp;Andrea Sierra Ramírez ,&nbsp;Mariana Restrepo Arias ,&nbsp;Natalia Betancourt Rodriguez ,&nbsp;Francisco José Molina Saldarriaga ,&nbsp;Fabian A. Jaimes B. ,&nbsp;Jorge E. Osorio ,&nbsp;Juan Pablo Hernández Ortiz","doi":"10.1016/j.acci.2024.05.001","DOIUrl":"10.1016/j.acci.2024.05.001","url":null,"abstract":"<div><div>We are currently contending with a significant consequence of the SARS-CoV-2 virus pandemic, termed post-COVID syndrome, which has escalated into another global crisis. Conservative estimates suggest that at least 76 million individuals worldwide are grappling with this condition, based on a projected 10% incidence rate among those previously infected. Daily, the tally of cases associated with this syndrome continues to mount. The emergence of long COVID has spurred intensified research endeavors, yet the current volume of ongoing studies falls short, and patient prognosis remains largely unchanged. Consequently, there is an urgent need for enhanced research methodologies to tackle this emerging condition effectively and to mount a robust response to the crisis. Management of post-COVID syndrome primarily revolves around symptomatic relief and rehabilitation strategies aimed at ameliorating the most prevalent symptoms that profoundly impact patients’ quality of life, such as fatigue, dyspnea, and loss of taste and smell. Despite sustained investigative efforts, specific treatments, including steroid therapies, have thus far failed to yield clinically significant outcomes. In this review, we delve into the multifaceted nature of post-COVID syndrome, exploring its impact, current management strategies, and the imperative for advancing research to better understand and address this pressing global health challenge.</div></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 4","pages":"Pages 387-397"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142659189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paciente joven con angina de Ludwig, mediastinitis necrosante descendente y shock séptico en relación con absceso odontogénico. Reporte de caso en Colombia 与牙源性脓肿有关的年轻路德维希心绞痛、下行性坏死性纵隔炎和脓毒性休克患者。哥伦比亚病例报告
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.05.012
Carlos Rebolledo Maldonado , Ricardo Luis Romero Figueroa , Evasandrid Romero Jiménez , Iván Alberto Salas Pinzón , Claudia Pacheco Escorcia , Jorge Salazar Amaris
Mediastinitis is a potentially fatal infection, and due to its low incidence, little epidemiological information is available. Complicated odontogenic infections, such as Ludwig's angina, are a rare cause of descending necrotizing mediastinitis but cause 90% of necrotizing infections. We present the case of a 34-year-old male patient with periodontal disease who develops Ludwig's angina. He progresses to descending necrotizing mediastinitis and septic shock, requiring emergency surgical management, ICU stay, invasive mechanical ventilation and broad-spectrum antibiotic management, with multiple complications associated with mediastinal involvement. Key aspects of the case such as epidemiology, physiopathology, diagnosis, and treatment of descending necrotizing mediastinitis secondary to odontogenic infections are analyzed. Ludwig's angina with descending necrotizing mediastinitis is a serious but preventable complication of this type of infections. Its management requires a timely multidisciplinary approach to reduce morbidity and mortality.
纵隔炎是一种可能致命的感染,由于发病率较低,目前几乎没有流行病学资料。复杂的牙源性感染,如路德维希心绞痛,是降级坏死性纵隔炎的罕见病因,但却可导致 90% 的坏死性感染。我们介绍了一例 34 岁男性牙周病患者的病例,他患上了路德维希心绞痛。他的病情发展为降级坏死性纵隔炎和脓毒性休克,需要紧急手术治疗、入住重症监护室、有创机械通气和广谱抗生素治疗,并伴有纵隔受累的多种并发症。本文对该病例的流行病学、生理病理学、诊断和治疗等关键方面进行了分析,以探讨继发于牙源性感染的降级坏死性纵隔炎。路德维希心绞痛伴降支性坏死性纵隔炎是这类感染的一种严重但可预防的并发症。其治疗需要及时采用多学科方法,以降低发病率和死亡率。
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引用次数: 0
Utilidad del PCR múltiplex de hemocultivo para el diagnóstico microbiológico de infecciones nosocomiales del sistema nervioso central en pacientes críticos 血液培养多重 PCR 在重症患者中枢神经系统院内感染的微生物学诊断中的实用性。
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.08.002
Sofía Mauro , Federico Verga , Antonio Galiana , Mariela Vieytes , Marcelo Barbato

Background and objective

To determine the usefulness of a molecular biology technique for nucleic acid amplification using real-time polymerase chain reaction (PCR) originally designed for microbiological diagnosis in blood cultures, when applied to cerebrospinal fluid (CSF) samples.

Materials and methods

Retrospective, observational, single-center study, carried out between January 2017 and February 2024 in a 28-bed multipurpose critical care unit. All patients with suspected postneurosurgical infection and CSF cytochemical alterations were included. In addition to the microbiological study of the CSF by traditional methods, the BioFire® Blood Culture Identification 2 (BCID) panel was applied directly to CSF samples. Traditional culture methods were considered as the reference standard for microbiological identification. The main variable of interest was the percentage of concordance of microbial identification between traditional cultures and BCID.

Results

29 patients were included. The diagnosis of central nervous system infection was confirmed in 14 cases (48.2%), 7 post-neurosurgical meningitis, 6 infections associated with ventriculostomy and 1 subdural empyema. The most frequently found microorganisms were Acinetobacter baumannii and Klebsiella pneumoniae. No discordances were found between PCR and cultures, so both the positive (14/14) and negative identification concordance (15/15) were 100% between both methods.

Conclusions

In patients with suspected post-neurosurgical infection and compatible CSF alterations, multiplex PCR blood cultures applied directly to CSF samples could be considered a useful and accurate tool for rapid microbiological diagnosis in infections of the central nervous system.
背景和目的确定使用实时聚合酶链反应(PCR)进行核酸扩增的分子生物学技术在脑脊液(CSF)样本中的实用性。材料和方法2017 年 1 月至 2024 年 2 月期间,在一家拥有 28 张床位的多功能重症监护病房开展了一项回顾性、观察性、单中心研究。纳入了所有疑似神经外科术后感染和 CSF 细胞化学改变的患者。除了用传统方法对 CSF 进行微生物学研究外,BioFire® 血液培养鉴定 2(BCID)面板也直接应用于 CSF 样本。传统的培养方法被视为微生物鉴定的参考标准。研究的主要变量是传统培养方法与 BCID 微生物鉴定的一致性百分比。其中 14 例(48.2%)确诊为中枢神经系统感染,7 例为神经外科手术后脑膜炎,6 例为脑室造口术相关感染,1 例为硬膜下积液。最常发现的微生物是鲍曼不动杆菌和肺炎克雷伯菌。结论 对于疑似神经外科手术后感染并伴有脑脊液改变的患者,直接对脑脊液样本进行多重 PCR 血培养可被视为中枢神经系统感染微生物快速诊断的有用而准确的工具。
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引用次数: 0
Desnutrición carencial al ingreso en pacientes intervenidos quirúrgicamente sobre el tubo digestivo 胃肠道手术患者的入院缺乏性营养不良
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.03.002
Yordanys Paez Candelaria , Lázaro Ibrahim Romero García , Karima Maricel Gondres Legró , Pedro Alexei Bacardí Zapata

Objectives

To characterize the population of critically ill patients, surgically operated on digestive tract, according to selected epidemiological, clinical and nutritional variables, as well as to determine the predictive load of the nutritional status on admission on unfavorable clinical evolution.

Design

Frame of reference and patients: An applied, explanatory, analytical cohort research was carried out from January 2023 to December 2023 in critically ill patients surgically operated on digestive tract, who were admitted to the Intensive and Intermediate Care Service of the “Saturnino Lora” Provincial Hospital in Santiago de Cuba.

Measurements

A nutritional profile was carried out, which included anthropometric, biochemical, and immunological indicators, which allowed the classification of the patients as malnourished and nourished.

Results

There was a predominance of males (51.85%), albumin was altered in 35.15% and 32.99% at admission and discharge, respectively. Acute hemorrhagic abdomen accounted for 39.51% of the total. Malnutrition was 44.44% at admission and 59.25% at discharge. The logistic regression model estimated that malnutrition at the patient's admission is a significant causal factor (p = 0.000) of unfavorable evolution in the population of patients exposed to this risk [OR = 6.95; I.C 95%: 2,55; 18,91]

Conclusions

Deficiency malnutrition on admission has a high incidence in patients surgically operated on digestive tract in the intensive care unit, who have a high probability of suffering complications during their stay, evolving unfavorably during the postoperative period.
目标根据选定的流行病学、临床和营养变量,确定接受消化道手术的重症患者的特征,并确定入院时的营养状况对不利临床演变的预测负荷:一项应用性、解释性和分析性队列研究于 2023 年 1 月至 2023 年 12 月进行,研究对象为古巴圣地亚哥 "萨图里诺-洛拉 "省立医院重症和中级护理服务部收治的消化道手术重症患者。结果男性居多(51.85%),入院和出院时分别有35.15%和32.99%的患者白蛋白发生变化。急性出血性腹部占总数的 39.51%。入院时营养不良者占 44.44%,出院时占 59.25%。根据逻辑回归模型估计,患者入院时营养不良是导致该风险患者群体发生不利演变的重要因果因素(P = 0.000)[OR = 6.95;I.C 95%:2,55;18,91]结论在重症监护室接受消化道手术的患者中,入院时营养不良的发生率很高,这些患者在住院期间极有可能出现并发症,并在术后发生不利演变。
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引用次数: 0
Parálisis hipopotasémica familiar: reporte de caso 家族性低钾性麻痹:病例报告
Pub Date : 2024-10-01 DOI: 10.1016/j.acci.2024.03.004
Deivi Barrios Andradez , Edgardo Gonzalez Puche , Rafael Orozco Marun , Johana Criado Urzola , Daniela Páez Jiménez
Familial hypokalemic paralysis is a rare muscular channelopathy, predominantly in males, characterized by generalized muscle weakness associated with hypokalemia, with complete recovery of symptoms after normalization of serum potassium levels; The main triggers are cessation of effort after strenuous exercise and carbohydrate-rich dinners. Below we present the case of a male adolescent with a family history of a similar condition, who after high carbohydrate intake presents with the first episode of acute muscle weakness associated with severe hypokalemia, whose symptoms resolve with the correction of the electrolyte disorder, thus meeting the criteria. Diagnoses of familial hypokalemic paralysis. The main lesson that this case leaves us is that although it is a rare disease, its suspected diagnosis should be included in a patient with muscle weakness.
家族性低钾性麻痹是一种罕见的肌肉通道病变,主要发生在男性身上,其特点是全身肌肉无力并伴有低钾血症,在血清钾水平恢复正常后症状会完全恢复;主要诱因是剧烈运动后停止用力和晚餐摄入大量碳水化合物。下面我们将介绍一例有类似家族史的男性青少年病例,他在摄入大量碳水化合物后首次出现急性肌无力,并伴有严重的低钾血症,在纠正电解质紊乱后症状缓解,因此符合标准。家族性低钾麻痹的诊断。本病例留给我们的主要启示是,虽然这是一种罕见疾病,但在出现肌无力的患者中应包括其可疑诊断。
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引用次数: 0
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Acta Colombiana de Cuidado Intensivo
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