{"title":"Cover Image, Volume 72, Issue 10","authors":"Martha M. Rangel-Sosa, Fanny Mann, Sophie Chauvet","doi":"10.1002/glia.24411","DOIUrl":null,"url":null,"abstract":"<p>Cover Illustration: 3D remodeling of reprogrammed non-myelinated Schwann cells and their associated sympathetic axons in metaplastic pancreatic lesions compared to adjacent tissue. 3D visualization of a cleared pancreatic section from a mouse with chronic pancreatitis. The transparent purple volume encompassed a metaplastic lesion with increased density of Schwann cells (in red) and sympathetic axons (in green), while the blue volume represents adjacent tissue with minimal metaplastic and neural changes. Schwann cells were labeled with anti-GFRA3, sympathetic axons with anti-TH and metaplastic cells with anti-CK19, in cyan. (See Chauvet, S., et al, https://doi.org/10.1002/glia.24586)\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":174,"journal":{"name":"Glia","volume":"72 10","pages":"C1"},"PeriodicalIF":5.4000,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/glia.24411","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Glia","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/glia.24411","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Cover Illustration: 3D remodeling of reprogrammed non-myelinated Schwann cells and their associated sympathetic axons in metaplastic pancreatic lesions compared to adjacent tissue. 3D visualization of a cleared pancreatic section from a mouse with chronic pancreatitis. The transparent purple volume encompassed a metaplastic lesion with increased density of Schwann cells (in red) and sympathetic axons (in green), while the blue volume represents adjacent tissue with minimal metaplastic and neural changes. Schwann cells were labeled with anti-GFRA3, sympathetic axons with anti-TH and metaplastic cells with anti-CK19, in cyan. (See Chauvet, S., et al, https://doi.org/10.1002/glia.24586)
封面插图:与邻近组织相比,变性胰腺病变中重新编程的非髓鞘化许旺细胞及其相关交感神经轴突的三维重塑。慢性胰腺炎小鼠胰腺切片的三维可视化。透明的紫色区域包括变性病灶,其中许旺细胞(红色)和交感神经轴突(绿色)密度增加,而蓝色区域代表变性和神经变化最小的邻近组织。用抗-GFRA3标记许旺细胞,用抗-TH标记交感神经轴突,用抗-CK19标记变性细胞(青色)。(见 Chauvet, S. 等人,https://doi.org/10.1002/glia.24586)
期刊介绍:
GLIA is a peer-reviewed journal, which publishes articles dealing with all aspects of glial structure and function. This includes all aspects of glial cell biology in health and disease.