Irisin in thyroid diseases

IF 3.2 3区 医学 Q2 MEDICAL LABORATORY TECHNOLOGY Clinica Chimica Acta Pub Date : 2024-08-21 DOI:10.1016/j.cca.2024.119929
Qi Chen , Jing Wang , Kang Li , Jun-Qin Luan , Jing-Mei Li , Ya-Ting Wang
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Abstract

Irisin, a hormone-like adipo-myokine, has garnered considerable attention in recent years for its potential impact in metabolic diseases. Its physiological effects are similar to those of thyroid hormones, prompting numerous investigations into potential correlations and interactions between irisin and thyroid function through various in vitro and animal experiments. However, existing studies suggest that the relationship between irisin and thyroid diseases is highly complex and multifaceted. In this paper, we have summarized the research results on serum irisin and thyroid function, providing an overview of advancements and constraints in current research on irisin and thyroid hormones. The aim is to offer insights and directions for future clinical trials in this field.

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甲状腺疾病中的鸢尾素
鸢尾素是一种类似激素的脂肪代谢物,近年来因其对代谢性疾病的潜在影响而备受关注。鸢尾素的生理效应与甲状腺激素相似,这促使人们通过各种体外和动物实验对鸢尾素与甲状腺功能之间的潜在关联和相互作用进行了大量研究。然而,现有研究表明,鸢尾素与甲状腺疾病之间的关系是非常复杂和多方面的。本文总结了有关血清鸢尾素和甲状腺功能的研究成果,概述了当前鸢尾素和甲状腺激素研究的进展和局限。目的是为该领域未来的临床试验提供见解和方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinica Chimica Acta
Clinica Chimica Acta 医学-医学实验技术
CiteScore
10.10
自引率
2.00%
发文量
1268
审稿时长
23 days
期刊介绍: The Official Journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Clinica Chimica Acta is a high-quality journal which publishes original Research Communications in the field of clinical chemistry and laboratory medicine, defined as the diagnostic application of chemistry, biochemistry, immunochemistry, biochemical aspects of hematology, toxicology, and molecular biology to the study of human disease in body fluids and cells. The objective of the journal is to publish novel information leading to a better understanding of biological mechanisms of human diseases, their prevention, diagnosis, and patient management. Reports of an applied clinical character are also welcome. Papers concerned with normal metabolic processes or with constituents of normal cells or body fluids, such as reports of experimental or clinical studies in animals, are only considered when they are clearly and directly relevant to human disease. Evaluation of commercial products have a low priority for publication, unless they are novel or represent a technological breakthrough. Studies dealing with effects of drugs and natural products and studies dealing with the redox status in various diseases are not within the journal''s scope. Development and evaluation of novel analytical methodologies where applicable to diagnostic clinical chemistry and laboratory medicine, including point-of-care testing, and topics on laboratory management and informatics will also be considered. Studies focused on emerging diagnostic technologies and (big) data analysis procedures including digitalization, mobile Health, and artificial Intelligence applied to Laboratory Medicine are also of interest.
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