Lauren E Tueth, Ryan P Duncan, Beth E Crowner, Gammon M Earhart
{"title":"Comparing balance using the BESTest in Alzheimer, Huntington and Parkinson disease.","authors":"Lauren E Tueth, Ryan P Duncan, Beth E Crowner, Gammon M Earhart","doi":"10.1080/17582024.2024.2388507","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aim:</b> Individuals with Alzheimer disease (AD), Huntington disease (HD) and Parkinson disease (PD) have impaired balance, and comparing these deficits could improve management of neurological diseases.<b>Methods:</b> Scores on the Balance Evaluation Systems Test (BESTest) were compared across three groups, consisting of individuals with AD, HD and PD in early stages of their respective disease.<b>Results:</b> Individuals with PD had significantly higher scores on the BESTest than individuals with AD (95% CI [4.30, 21.37], <i>p</i> < 0.01) or HD (95% CI [6.53, 24.18], <i>p</i> < 0.001). Individuals with AD and HD were not significantly different on the overall BESTest or any of its subsections.<b>Conclusion:</b> AD and HD may have overlapping pathologies resulting in early and similar balance impairments in these groups.</p>","PeriodicalId":19114,"journal":{"name":"Neurodegenerative disease management","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurodegenerative disease management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17582024.2024.2388507","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: Individuals with Alzheimer disease (AD), Huntington disease (HD) and Parkinson disease (PD) have impaired balance, and comparing these deficits could improve management of neurological diseases.Methods: Scores on the Balance Evaluation Systems Test (BESTest) were compared across three groups, consisting of individuals with AD, HD and PD in early stages of their respective disease.Results: Individuals with PD had significantly higher scores on the BESTest than individuals with AD (95% CI [4.30, 21.37], p < 0.01) or HD (95% CI [6.53, 24.18], p < 0.001). Individuals with AD and HD were not significantly different on the overall BESTest or any of its subsections.Conclusion: AD and HD may have overlapping pathologies resulting in early and similar balance impairments in these groups.
目的：阿尔茨海默病（AD）、亨廷顿病（HD）和帕金森病（PD）患者的平衡能力受损，比较这些缺陷可改善神经系统疾病的管理：结果：帕金森病患者在平衡评估系统测试（BESTest）中的得分在三组患者中进行了比较：结果：帕金森病患者的 BESTest 得分明显高于 AD 患者（95% CI [4.30, 21.37]，p p 结论：AD 和 HD 的病理特征可能存在重叠：AD和HD可能存在重叠病理，导致这两类患者在早期出现类似的平衡障碍。
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
