Symptom Burden Contributes to Sleep Problems Through Depressive Symptoms in Middle-Aged and Older Adults With Type 2 Diabetes: A Multigroup Analysis.

Min Jung Kim, Eunjin Yang, Chang Park, Eunhee Cho, Cynthia Fritschi
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Abstract

Purpose: The purpose of this study was to examine the relationships between symptom burden and sleep problems and the role of depressive symptoms on these relationships in middle-aged and older adults with type 2 diabetes.

Methods: The study employed a cross-sectional, correlational design with secondary analysis. De-identified data sets from three original studies were combined. A total of 189 men and women with type 2 diabetes were recruited using convenience sampling in midwestern United States. Symptom burden, sleep impairment and sleep disturbance, depressive symptoms, demographics, and diabetes-related variables were assessed. The participants were grouped into glucose-controlled and -uncontrolled groups to examine a multigroup effect. Multigroup path analyses were conducted.

Results: The results indicated that symptom burden had direct and indirect effects through depressive symptoms on sleep disturbance in the controlled group, whereas only a direct effect was found in the uncontrolled group. For sleep-related impairment, significant direct and indirect effects of symptom burden were found via depressive symptoms in both groups, and the strength of the effects on each path differed between the groups.

Conclusions: Diabetes symptom burden was associated with sleep disturbance and sleep-related impairment in middle-aged and older adults with diabetes. A different approach should be considered for sleep management according to their A1C levels, and depressive symptoms can be a therapeutic target to treat sleep problems in the population.

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症状负担通过抑郁症状导致中老年 2 型糖尿病患者的睡眠问题:多组分析
目的:本研究旨在探讨中老年 2 型糖尿病患者的症状负担与睡眠问题之间的关系,以及抑郁症状对这些关系的影响:研究采用横断面相关设计,并进行二次分析。研究采用了横断面相关性设计,并进行了二次分析,合并了三项原始研究的去身份化数据集。在美国中西部地区采用便利抽样法共招募了 189 名男性和女性 2 型糖尿病患者。对症状负担、睡眠障碍和睡眠干扰、抑郁症状、人口统计学和糖尿病相关变量进行了评估。将参与者分为血糖控制组和未控制组,以研究多组效应。进行了多组路径分析:结果表明,在血糖控制组中,症状负担通过抑郁症状对睡眠障碍产生直接和间接影响,而在未控制组中只发现了直接影响。对于睡眠相关障碍,在两组中都发现了症状负担通过抑郁症状产生的明显的直接和间接影响,而且各组之间影响的强度不同:结论:糖尿病症状负担与中老年糖尿病患者的睡眠障碍和睡眠相关损害有关。结论:糖尿病症状负担与中老年糖尿病患者的睡眠障碍和睡眠相关损害有关,应根据他们的 A1C 水平考虑采取不同的睡眠管理方法,抑郁症状可作为治疗目标来治疗人群中的睡眠问题。
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