Uso correcto de inhaladores en adultos: del conocimiento a la aplicación

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI:10.1016/j.rmclc.2024.07.002
Carlos Horta , Loreto Sáez , Jorge Jorquera
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Abstract

The administration of drugs via inhalation has become the primary route for treating obstructive pulmonary diseases. In this context, the efficient deposition of medication particles in the airway plays a fundamental role in the effectiveness of inhaled therapy, offering superior benefits in terms of speed and reduction of systemic effects compared to other routes of administration. It is crucial to ensure that a sufficient amount of medication reaches beyond the oropharyngeal region to guarantee therapeutic effectiveness. Among the available devices for this form of administration, pressurized metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs) are the most commonly used. It is worth mentioning that nebulization devices are not covered in this review.

Although the diversity of therapeutic options is beneficial, the availability of different devices can create some complexity when instructing patients on their proper use. Consequently, it is vital for patients to precisely follow the recommended inhalation technique. Errors in device handling can lead to improper drug distribution, reducing the effective dose and compromising treatment efficacy. This review provides detailed explanations of the mechanism of action of these devices, as well as practical instructions for patient care personnel. Emphasis is placed on the importance of correct inhalation technique to maximize treatment efficacy and ensure optimal drug use.

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成人正确使用吸入器:从认知到应用
通过吸入给药已成为治疗阻塞性肺病的主要途径。在这种情况下,药物微粒在气道中的有效沉积对吸入治疗的效果起着至关重要的作用,与其他给药途径相比,吸入治疗在速度和减少全身影响方面具有更优越的优势。确保有足够的药物到达口咽部以外的区域以保证治疗效果至关重要。在现有的给药设备中,加压计量吸入器(pMDIs)和干粉吸入器(DPIs)最为常用。值得一提的是,本综述不包括雾化吸入装置。虽然治疗选择的多样性是有益的,但在指导患者正确使用这些装置时,不同装置的可用性可能会造成一定的复杂性。因此,患者必须严格遵守推荐的吸入技术。设备操作错误会导致药物分布不当,降低有效剂量,影响治疗效果。本综述详细解释了这些设备的作用机制,并为患者护理人员提供了实用指导。重点强调了正确的吸入技术对于最大限度地提高治疗效果和确保最佳药物使用的重要性。
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来源期刊
Revista Medica Clinica Las Condes
Revista Medica Clinica Las Condes MEDICINE, GENERAL & INTERNAL-
CiteScore
0.80
自引率
0.00%
发文量
65
审稿时长
81 days
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