Putting together pieces of the LIN28A pathway puzzle

IF 12.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature Structural & Molecular Biology Pub Date : 2024-08-21 DOI:10.1038/s41594-024-01380-w
Alperen Yilmaz, Gulben Gurhan, Jacob H. Hanna
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Abstract

Two recent studies provide mechanistic insights into how LIN28A controls changes in cell fate identity, focusing on either a let-7-independent or let-7-dependent pathway of action involving LIN28A.

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拼凑 LIN28A 通路拼图
最近的两项研究从机理上揭示了 LIN28A 如何控制细胞命运特征的变化,重点研究了 LIN28A 依赖或不依赖 let-7 的作用途径。
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来源期刊
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS
CiteScore
22.00
自引率
1.80%
发文量
160
审稿时长
3-8 weeks
期刊介绍: Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.
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