Associations of oxidative balance score with lumbar spine osteopenia in 20-40 years adults: NHANES 2011-2018.

IF 2.6 3区医学 Q2 CLINICAL NEUROLOGY European Spine Journal Pub Date : 2024-09-01 Epub Date: 2024-08-21 DOI:10.1007/s00586-024-08424-1

Yu-Ao Tao, Ling Long, Jia-Xiang Gu, Pei-Yang Wang, Xi Li, Xiao-Long Li, Pan Fan, Yuntao Wang

{"title":"Associations of oxidative balance score with lumbar spine osteopenia in 20-40 years adults: NHANES 2011-2018.","authors":"Yu-Ao Tao, Ling Long, Jia-Xiang Gu, Pei-Yang Wang, Xi Li, Xiao-Long Li, Pan Fan, Yuntao Wang","doi":"10.1007/s00586-024-08424-1","DOIUrl":null,"url":null,"abstract":"Purpose: Current research suggests that oxidative stress may decrease bone mineral density (BMD) by disrupting bone metabolism balance. However, no study investigated the relationship between systemic oxidative stress status and adult BMD. This study aims to investigate whether oxidative balance score (OBS) is associated with BMD in adults under 40.Methods: 3963 participants were selected from the National Health and Nutrition Survey (NHANES) from 2011 to 2018. OBS is scored based on 20 dietary and lifestyle factors. Weighted multiple logistic regression and restricted cubic splines were used to assess the correlation between OBS and osteopenia.Results: After adjusting for confounding factors, the weighted logistic regression results showed that compared with the first tertile of OBS, the highest tertile had a 38% (OR: 0.62, 95% CI: 0.47-0.82) lower risk of osteopenia. The restrictive cubic spline curve indicates a significant nonlinear correlation between OBS and the risk of osteopenia.Conclusion: The research findings emphasize the relationship between OBS and the risk of osteopenia in young adults. Adopting an antioxidant diet and lifestyle may help young adults to maintain bone mass.","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Spine Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00586-024-08424-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/21 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Current research suggests that oxidative stress may decrease bone mineral density (BMD) by disrupting bone metabolism balance. However, no study investigated the relationship between systemic oxidative stress status and adult BMD. This study aims to investigate whether oxidative balance score (OBS) is associated with BMD in adults under 40.

Methods: 3963 participants were selected from the National Health and Nutrition Survey (NHANES) from 2011 to 2018. OBS is scored based on 20 dietary and lifestyle factors. Weighted multiple logistic regression and restricted cubic splines were used to assess the correlation between OBS and osteopenia.

Results: After adjusting for confounding factors, the weighted logistic regression results showed that compared with the first tertile of OBS, the highest tertile had a 38% (OR: 0.62, 95% CI: 0.47-0.82) lower risk of osteopenia. The restrictive cubic spline curve indicates a significant nonlinear correlation between OBS and the risk of osteopenia.

Conclusion: The research findings emphasize the relationship between OBS and the risk of osteopenia in young adults. Adopting an antioxidant diet and lifestyle may help young adults to maintain bone mass.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

20-40岁成年人氧化平衡评分与腰椎骨质增生的关系2011-2018 年国家健康调查。

目的：目前的研究表明，氧化应激可能会破坏骨代谢平衡，从而降低骨矿物质密度（BMD）。然而，还没有研究调查过全身氧化应激状态与成人骨密度之间的关系。本研究旨在调查氧化平衡评分（OBS）是否与 40 岁以下成年人的 BMD 相关。方法：从 2011 年至 2018 年的美国国家健康与营养调查（NHANES）中选取了 3963 名参与者。OBS根据20个饮食和生活方式因素进行评分。采用加权多元逻辑回归和限制性立方样条来评估OBS与骨质疏松症之间的相关性：调整混杂因素后，加权逻辑回归结果显示，与 OBS 的第一分位数相比，最高分位数的人患骨质疏松症的风险降低了 38%（OR：0.62，95% CI：0.47-0.82）。限制性立方样条曲线表明，OBS 与骨质增生风险之间存在显著的非线性相关性：研究结果强调了OBS与青壮年骨质增生风险之间的关系。采用抗氧化饮食和生活方式可能有助于青壮年保持骨量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

European Spine Journal 医学-临床神经学

CiteScore

4.80

自引率

10.70%

发文量

373

审稿时长

2-4 weeks

期刊介绍： "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe