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Old technique, new applications: can the H-reflex be a possible real-time indicator in endoscopic surgery for decompression of acute disc herniation at the S1 root? 旧技术,新应用:h反射能否成为内镜手术治疗急性S1根椎间盘突出减压的实时指标?
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-19 DOI: 10.1007/s00586-025-09634-x
Marta Rodrigues Carvalho, Vitor Caldas Marques, Baldomero Pinto Soares, Gabriel Pokorny, Thiego Pedro, Mario Bringel, Rodrigo Grion

Background: The Hoffmann (H-) reflex is a monosynaptic electrophysiological response that reflects S1-root integrity. Although widely used in experimental and in clinical outpatient neurophysiological testing, its intra-operative application during endoscopic lumbar surgery is rarely reported. We present the first real-time documentation of H-reflex normalization immediately after endoscopic decompression of an acute L5-S1 disc herniation.

Case description: A 49-year-old woman presented with acute right-sided S1 radiculopathy (ankle dorsiflexion/plantar-flexion MRC grade III; hallux extension grade I). MRI showed a large, right sub-articular L5-S1 disc extrusion compressing the S1 nerve root. Unilateral biportal endoscopic discectomy was performed under general anesthesia with multimodal intra-operative neuromonitoring (MEPs, free-run EMG, and continuous tibial-nerve H-reflex). Baseline recordings revealed marked side-to-side asymmetry: right-leg MEP amplitudes were depressed, and the right H-reflex was low and unstable. During foraminoplasty and fragment removal, a sudden, sustained 100% surge in right H-reflex amplitude occurred, coincidence with root decompression, while MEPs remained unchanged. Free-run EMG discharges abated after the H-reflex improved. Post-operative recovery was uneventful. At 2 months the patient demonstrated near-complete motor recovery (MRC IV-V) and full pain relief.

Conclusion: Continuous H-reflex monitoring provided an immediate, sensitive marker of S1-root decompression when conventional MEPs failed to reflect functional recovery. This single-case experience supports the feasibility and potential prognostic value of adding H-reflex surveillance to the neuromonitoring toolkit for endoscopic lumbar surgery. Prospective studies in larger cohorts are warranted to validate threshold criteria, refine stimulation parameters, and determine cost-effectiveness.

背景:Hoffmann (H-)反射是一种反映s1根完整性的单突触电生理反应。虽然广泛用于实验和临床门诊神经生理检测,但其在腰椎内镜手术中的术中应用却很少报道。我们提出了急性L5-S1椎间盘突出症内镜减压后立即h反射正常化的第一个实时记录。病例描述:一名49岁女性,表现为急性右侧S1神经根病(踝关节背屈/跖屈MRC III级;拇伸I级)。MRI显示右侧大的关节下L5-S1椎间盘挤压S1神经根。全麻下行单侧双门静脉内窥镜椎间盘切除术,术中多模式神经监测(mep、自由行肌电图和连续胫骨神经h反射)。基线记录显示明显的左右不对称:右腿MEP振幅下降,右侧h反射低且不稳定。在椎间孔成形术和碎片去除过程中,右h反射振幅突然持续100%激增,与根减压一致,而MEPs保持不变。h反射改善后自由运动肌电图放电减弱。术后恢复顺利。2个月时,患者表现出接近完全的运动恢复(MRC IV-V)和完全疼痛缓解。结论:当常规mep不能反映功能恢复时,连续h反射监测提供了快速、敏感的s1根减压标志。这一单一病例的经验支持了在腰椎内窥镜手术的神经监测工具包中增加h反射监测的可行性和潜在的预后价值。在更大的队列中进行前瞻性研究是有必要的,以验证阈值标准,完善刺激参数,并确定成本效益。
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引用次数: 0
Correction: The higher cellular elastic modulus of the nucleus pulposus with degenerative changes in the cervical intervertebral discs. 矫正:髓核较高的细胞弹性模量伴颈椎间盘退行性改变。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-19 DOI: 10.1007/s00586-025-09604-3
Bowei Xiao, Tianchi Zhou, Juying Huang, Tianhua Rong, Bingxuan Wu, Baoge Liu
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引用次数: 0
Analysis of risk factors for deep vein thrombosis after lumbar endoscopic single-segment decompression without fusion. 腰椎内镜单节段无融合减压术后深静脉血栓形成危险因素分析。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09591-5
Zhiqiang Wang, Jianguo Zhang, Yongzhuang Ma, Liming He, Yue Wang, Haoyu Feng, Lin Sun
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引用次数: 0
Metagenomic next-generation sequencing for the diagnosis of suspected spinal infections from biopsy samples: a novel biopsy toolkit design and real-life diagnostic value. 从活检样本中诊断疑似脊柱感染的新一代宏基因组测序:一种新的活检工具包设计和现实生活中的诊断价值。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09686-z
Zhuoyue Li, Shangjie Yang, Chaoran Li, Lin Zhang, Na Xi, Dawei Li, Litao Li
{"title":"Metagenomic next-generation sequencing for the diagnosis of suspected spinal infections from biopsy samples: a novel biopsy toolkit design and real-life diagnostic value.","authors":"Zhuoyue Li, Shangjie Yang, Chaoran Li, Lin Zhang, Na Xi, Dawei Li, Litao Li","doi":"10.1007/s00586-025-09686-z","DOIUrl":"https://doi.org/10.1007/s00586-025-09686-z","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Announcements. 公告。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09658-3
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引用次数: 0
Letter to the Editor concerning "Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery" by Ahonen, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y). Ahonen等人关于“脑瘫患儿肺炎死亡率和肺炎风险”的致编辑信(Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y)。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09694-z
Changzhu Lu, Long Zheng
{"title":"Letter to the Editor concerning \"Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery\" by Ahonen, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y).","authors":"Changzhu Lu, Long Zheng","doi":"10.1007/s00586-025-09694-z","DOIUrl":"https://doi.org/10.1007/s00586-025-09694-z","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic lumbar decompression in patients with obesity does not correlate with inferior outcomes. 肥胖患者的内镜下腰椎减压与不良预后无关。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09682-3
Joshua G Sanchez, Julian Smith-Voudouris, Katie M Zehner, Scott J Halperin, Sahir S Jabbouri, Anthony E Seddio, Daniel R Rubio, Jonathan N Grauer

Purpose: Endoscopic spine surgery (ESS) may reduce perioperative risks traditionally associated with obesity in open lumbar procedures. This study evaluated 90-day complications, healthcare utilization, and insurer-payments in obese versus non-obese patients undergoing endoscopic lumbar decompression.

Methods: A national administrative database was queried for adults undergoing endoscopic lumbar decompression from January 2017 to April 2023. Patients with trauma, neoplasm, or infection within 90-days preoperatively or < 90-day follow-up postoperatively were excluded. Cohorts were stratified by obesity (body mass index > 30 kg/m²). Demographics, 90-day complications (any, severe, minor), and healthcare utilization (emergency department visits, readmissions, physical therapy) were compared using univariable tests and multivariable logistic regression adjusting for age, sex, Elixhauser Comorbidity Index, smoking, type 2 diabetes, hypertension, obstructive sleep apnea, and surgical indication (stenosis vs. disc herniation). Ninety-day insurer payments were compared using a Wilcoxon rank-sum test.

Results: A total of 1,989 patients met criteria (1618 non-obese; 371 obese). On univariable and multivariable analysis, obesity was not associated with increased odds of any 90-day complication or healthcare-utilization outcome. Median (25th quartile, 75th quartile) 90-day insurer-payments were $2563 ($1074, 5124) for non-obese patients and $3310 ($1572, 5784) for obese patients (p = 0.0003).

Conclusion: This study demonstrated obesity was not associated with increased odds of 90-day complications or healthcare utilization in the adjusted models. However, obese patients incurred higher insurer-paid costs, underscoring important clinical and policy considerations. As ESS becomes increasingly utilized, future work should examine patient-reported outcomes, longer-term complications, and reoperation-free survival in obese patients as well as in populations with other comorbidities.

目的:内窥镜脊柱手术(ESS)可以降低开放式腰椎手术中传统上与肥胖相关的围手术期风险。本研究评估了肥胖与非肥胖患者在内镜下腰椎减压术中90天的并发症、医疗保健利用和保险支付情况。方法:查询2017年1月至2023年4月接受内窥镜腰椎减压术的成年人的国家管理数据库。术前90天内有外伤、肿瘤或感染或30 kg/m²的患者。采用单变量检验和多变量logistic回归对年龄、性别、Elixhauser合并症指数、吸烟、2型糖尿病、高血压、阻塞性睡眠呼吸暂停和手术指征(狭窄vs椎间盘突出)进行校正,比较人口统计学、90天并发症(任何、严重、轻微)和医疗保健利用(急诊就诊、再入院、物理治疗)。使用Wilcoxon秩和检验比较90天保险公司付款。结果:共有1989例患者符合标准(1618例非肥胖;371例肥胖)。在单变量和多变量分析中,肥胖与任何90天并发症或医疗保健利用结果的几率增加无关。非肥胖患者90天保险赔付中位数(第25、75四分位数)为2563美元(1074、5124美元),肥胖患者为3310美元(1572、5784美元)(p = 0.0003)。结论:本研究表明,在调整后的模型中,肥胖与90天并发症或医疗保健利用率增加的几率无关。然而,肥胖患者承担了更高的保险支付费用,强调了重要的临床和政策考虑。随着ESS越来越多的应用,未来的工作应该检查患者报告的结果、长期并发症和肥胖患者以及其他合并症人群的无再手术生存率。
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引用次数: 0
Answer to the Letter to the Editor of H. Wang, et al. concerning "5G-Enabled remote Robotic-Assisted percutaneous pedicle screw fixation in single thoracolumbar fractures: initial clinical feasibility and safety evaluation" by L. Zhou, et al. (Eur Spine J [2025]: doi: 10.1007/s00586-025-09478-5). 关于“5g远程机器人辅助经皮椎弓根螺钉内固定治疗单胸腰椎骨折:初步临床可行性和安全性评估”的答复,周磊,等。[2025]:doi: 10.1007/s00586-025-09478-5。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-16 DOI: 10.1007/s00586-025-09557-7
Lu-Ping Zhou, Xian-Liang Zhang, Hua-Qing Zhang, Yu Chen, Chong-Yu Jia, Peng Ge, Yong Zhang, Ao Liu, Ren-Jie Zhang, Cai-Liang Shen
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引用次数: 0
Evaluation of spinal canal and neural foramen areas in supine and prone positions in patients with lumbar stenosis. 腰椎管狭窄患者仰卧位和俯卧位椎管和神经孔面积的评价。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-16 DOI: 10.1007/s00586-025-09586-2
Baris Kucukyuruk, Huseyin Mert Cerci, Fatma Serra Kalyoncu, Irem Karaboga, Semih Can Cetintas, Osman Aykan Kargin, Bora Korkmazer, Serdar Arslan, Mehmet Murat Hanci
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引用次数: 0
Letter to the Editor concerning "Association between MRI findings and inflammatory symptoms in non-specific chronic low back pain" by K. Ziegeler, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09492-7). 关于“MRI结果与非特异性慢性腰痛炎症症状的相关性”的致编辑信,K. Ziegeler,等。[2025];doi: 10.1007/s00586-025-09492-7。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-16 DOI: 10.1007/s00586-025-09665-4
Shyam Sundar Sah, Abhishek Kumbhalwar
{"title":"Letter to the Editor concerning \"Association between MRI findings and inflammatory symptoms in non-specific chronic low back pain\" by K. Ziegeler, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09492-7).","authors":"Shyam Sundar Sah, Abhishek Kumbhalwar","doi":"10.1007/s00586-025-09665-4","DOIUrl":"https://doi.org/10.1007/s00586-025-09665-4","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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European Spine Journal
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