Evaluation of the safety and efficacy of concentrated growth factors for hair growth promotion in androgenetic alopecia patients: A retrospective single-centre, single-arm study.

IF 2.3 4区 医学 Q2 DERMATOLOGY Journal of Cosmetic Dermatology Pub Date : 2024-08-21 DOI:10.1111/jocd.16519
Saisai Cao, Mengyi Zhu, Ye Bi
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引用次数: 0

Abstract

Objective: This study was designed to evaluate the safety and efficacy of injections of concentrated growth factors (CGF) for hair growth promotion in androgenetic alopecia (AGA) patients.

Methods: A retrospective review of AGA patients treated with injections of CGF at our center from October 2021 to April 2023 was performed. A total of 3 injections were administered every 3-4 weeks apart, and evaluation were performed before the first injection and at 3 months, 6 months later. The outcomes were assessed by trichoscopy photomicrographs and the Global Aesthetic Improvement Scale (GAIS).

Results: At 3 months after the first injection, the hair density and hair growth ratio were significantly improved. Significant improvements were found in GAIS score by both patients and independent doctors and the hair growth promotion was sustained for 6 months after first treatment.

Conclusions: According to this tiny single-arm trial, the use of CGF injection may help AGA by increasing terminal hair density and hair density. No severe topical or systemic adverse events occurred during the treatment.

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评估浓缩生长因子促进雄激素性脱发患者毛发生长的安全性和有效性:单中心、单臂回顾性研究。
研究目的本研究旨在评估注射浓缩生长因子(CGF)促进雄激素性脱发(AGA)患者毛发生长的安全性和有效性:对2021年10月至2023年4月期间在本中心接受CGF注射治疗的AGA患者进行回顾性研究。每隔3-4周注射一次,共注射3次,在首次注射前、3个月后和6个月后进行评估。结果通过三镜显微照片和全球美学改善量表(GAIS)进行评估:结果:首次注射后 3 个月,毛发密度和毛发生长比例均有明显改善。结果:首次注射后 3 个月,毛发密度和毛发生长比例均有明显改善,患者和独立医生的 GAIS 评分均有明显改善,毛发生长促进作用在首次治疗后持续了 6 个月:结论:根据这项微小的单臂试验,CGF注射液可通过增加末端毛发密度和毛发密度来帮助AGA。治疗期间未发生严重的局部或全身不良反应。
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来源期刊
CiteScore
4.30
自引率
13.00%
发文量
818
审稿时长
>12 weeks
期刊介绍: The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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