Facility wastewater monitoring as an effective tool for pandemic infection control: An experience in COVID-19 pandemic with long-term monitoring.

IF 1.9 4区 医学 Q3 INFECTIOUS DISEASES Journal of Infection and Chemotherapy Pub Date : 2024-08-21 DOI:10.1016/j.jiac.2024.08.014
Shoko Tateishi, Kensuke Hamada, Noriko Emoto, Kazumi Abe, Koichi Abe, Yuki Kawasaki, Mitsuhiro Sunohara, Kyoji Moriya, Hiroyuki Katayama, Takeya Tsutsumi, Yoshinori Murakami, Yutaka Suzuki, Hiroshi Yotsuyanagi, Shintaro Yanagimoto
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Abstract

Introduction: Since the first report of a novel coronavirus infection caused by SARS-CoV-2 in late 2019, the infection has spread rapidly and had a significant impact on our lives. In the early stages of the COVID-19 pandemic, there was no adequate testing system in place, despite an urgent need for infection control measures in student dormitories.

Methods: We have been monitoring SARS-CoV-2 in wastewater as part of our infection control efforts in the university facilities since fall 2020. In the four dormitories, absorbent cotton was placed in the drains that the facility wastewater passed through, and samples were collected twice a week and processed by RT-PCR for SARS-CoV-2. The dormitory residents were informed of the monitoring results the next morning.

Results: The positivity of residents in the dormitories was highly consistent with the positivity of wastewater. Wastewater was positive in 89 % of cases before any residents were tested and found positive. Facility wastewater monitoring showed sensitivities of 80.4 % and specificities of 87.6 %. No traceable resident-to-resident transmission of infection within the facility was confirmed during the study period.

Conclusion: Sampling a single wastewater outlet in a building for SARS-CoV-2 PCR can effectively indicate the presence or absence of COVID-19 cases and be very useful for infection control of a facility. This simple and effective monitoring is applicable to future outbreaks of both emerging and re-emerging infectious diseases.

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将设施废水监测作为大流行病感染控制的有效工具:在 COVID-19 大流行中进行长期监测的经验。
导言:自2019年底首次报告由SARS-CoV-2引起的新型冠状病毒感染以来,该感染迅速蔓延,对我们的生活产生了重大影响。在 COVID-19 大流行的早期阶段,尽管迫切需要在学生宿舍采取感染控制措施,但却没有建立适当的检测系统。方法:方法:自 2020 年秋季以来,我们一直在监测废水中的 SARS-CoV-2 作为大学设施感染控制工作的一部分。在四栋宿舍楼中,将吸水棉放置在设施废水通过的排水沟中,每周收集两次样本,并通过 RT-PCR 对 SARS-CoV-2 进行处理。监测结果于第二天早上通知宿舍居民:结果:宿舍居民的阳性反应与废水的阳性反应高度一致。在对居民进行检测并发现阳性结果之前,89%的病例中废水呈阳性。设施废水监测的灵敏度为 80.4%,特异度为 87.6%。在研究期间,未证实设施内存在可追溯的居民间传染:结论:对建筑物中的单个废水排放口进行 SARS-CoV-2 PCR 采样可有效显示是否存在 COVID-19 病例,对设施内的感染控制非常有用。这种简单有效的监测方法适用于未来爆发的新发和再发传染病。
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来源期刊
Journal of Infection and Chemotherapy
Journal of Infection and Chemotherapy INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY
CiteScore
4.10
自引率
4.50%
发文量
303
审稿时长
47 days
期刊介绍: The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.
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