The significance of different intervertebral spaces in combined spinal epidural anesthesia in cesarean section.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.3233/THC-240599
Qing Yu, Jing Hu
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Abstract

Background: The number of cesarean sections performed is increasing every year, and obstetric anesthesia is of great interest to physicians and research scholars because of its specificity, high risk, and high complication rate.

Objective: To investigate the effects of combined spinal epidural anesthesia (CSEA) with different intervertebral spaces during cesarean section on anesthesia effect, anesthesia onset time, anesthesia recovery time, maternal adverse reactions, and neonates.

Methods: Ninety-two women who underwent cesarean section in our hospital from September 2022 to February 2023 were selected as the study subjects and randomly divided them into two groups (group A and group B), 46 women in each group. Group A underwent CSEA via an L2-3 gap and group B underwent CSEA via an L3-4 gap puncture. The anesthesia effect, anesthesia onset time, sensory recovery time, adverse effects, and neonatal Apgar score were compared between the two groups.

Results: When CSEA was performed from L2-3, the anesthesia efficiency was higher, but the difference was not statistically significant. When anesthesia was performed by puncture from L2-3, the onset of anesthesia and recovery time was shorter, and the incidence of intraoperative maternal nausea and vomiting, hypotension, respiratory depression, and other adverse reactions was low with a statistically significant difference. However, the Apgar scores of the neonates in the two groups have no difference.

Conclusions: When CSEA is induced via L2-3 interspace, anesthesia has a rapid onset of action, shorter recovery time, and few maternal adverse effects, without affecting the final anesthetic outcome.

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剖腹产联合脊髓硬膜外麻醉中不同椎间隙的意义。
背景:剖宫产手术的数量逐年增加,产科麻醉因其特异性、高风险和高并发症发生率而备受医生和研究学者的关注:目的:探讨剖宫产术中不同椎间隙联合脊髓硬膜外麻醉(CSEA)对麻醉效果、麻醉起效时间、麻醉恢复时间、产妇不良反应及新生儿的影响:选取2022年9月至2023年2月在我院进行剖宫产手术的92例产妇作为研究对象,随机分为两组(A组和B组),每组46例。A组通过L2-3间隙进行CSEA,B组通过L3-4间隙穿刺进行CSEA。比较两组的麻醉效果、麻醉开始时间、感觉恢复时间、不良反应和新生儿Apgar评分:结果:从L2-3进行CSEA时,麻醉效率较高,但差异无统计学意义。从L2-3穿刺进行麻醉时,麻醉起效时间和恢复时间较短,术中产妇恶心呕吐、低血压、呼吸抑制等不良反应发生率较低,差异有统计学意义。但两组新生儿的 Apgar 评分无差异:结论:通过 L2-3 椎间隙诱导 CSEA,麻醉起效快,恢复时间短,产妇不良反应少,且不影响最终麻醉效果。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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