Tissue Mimicking Materials for Shell-Based Phantoms in Breast Microwave Sensing

IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2024-03-29 DOI:10.1109/JERM.2024.3379747
Jordan Krenkevich;Gabrielle Fontaine;Evelyne Hluszok;Tyson Reimer;Stephen Pistorius
{"title":"Tissue Mimicking Materials for Shell-Based Phantoms in Breast Microwave Sensing","authors":"Jordan Krenkevich;Gabrielle Fontaine;Evelyne Hluszok;Tyson Reimer;Stephen Pistorius","doi":"10.1109/JERM.2024.3379747","DOIUrl":null,"url":null,"abstract":"Breast phantoms are required to test and evaluate microwave breast imaging systems before clinical applications. Shell-based breast phantoms are versatile, reproducible, low-cost, stable, and capable of mimicking the morphology and dielectric properties of the breast. In past work, 3D-printable plastics have been used to fabricate the shells in these phantoms, but the low permittivity plastics limit the dielectric accuracy of the phantoms. Furthermore, the liquids in these shell-based phantoms are prone to air bubbles, which may introduce undesirable microwave scattering. This work examines new tissue-mimicking materials to address these challenges. Low-permittivity 3D-printed plastic filament was replaced with a graphite, carbon-black, and resin mixture to mimic skin properties within the 0.4–9.0 GHz range. Glycerin and Triton X-100 were replaced by diethylene glycol butyl ether (DGBE) solutions to mimic the properties of adipose and fibroglandular tissue. The resin-based material more closely modelled the properties of ex vivo tissue samples than 3D-printed plastics. The DGBE solutions had improved dielectric properties compared to the glycerin and Triton X-100 solutions. The DGBE solutions are advantageous compared to glycerin and Triton X-100 solutions due to their lower viscosity, decreased susceptibility to air bubble formation, improved short-term stability, temperature stability, and enhanced long-term stability, facilitating the reusability of these materials. The materials investigated in this work can be used to produce more dielectrically accurate breast phantoms with improved stability and experimental utility for microwave breast imaging.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10485439/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0

Abstract

Breast phantoms are required to test and evaluate microwave breast imaging systems before clinical applications. Shell-based breast phantoms are versatile, reproducible, low-cost, stable, and capable of mimicking the morphology and dielectric properties of the breast. In past work, 3D-printable plastics have been used to fabricate the shells in these phantoms, but the low permittivity plastics limit the dielectric accuracy of the phantoms. Furthermore, the liquids in these shell-based phantoms are prone to air bubbles, which may introduce undesirable microwave scattering. This work examines new tissue-mimicking materials to address these challenges. Low-permittivity 3D-printed plastic filament was replaced with a graphite, carbon-black, and resin mixture to mimic skin properties within the 0.4–9.0 GHz range. Glycerin and Triton X-100 were replaced by diethylene glycol butyl ether (DGBE) solutions to mimic the properties of adipose and fibroglandular tissue. The resin-based material more closely modelled the properties of ex vivo tissue samples than 3D-printed plastics. The DGBE solutions had improved dielectric properties compared to the glycerin and Triton X-100 solutions. The DGBE solutions are advantageous compared to glycerin and Triton X-100 solutions due to their lower viscosity, decreased susceptibility to air bubble formation, improved short-term stability, temperature stability, and enhanced long-term stability, facilitating the reusability of these materials. The materials investigated in this work can be used to produce more dielectrically accurate breast phantoms with improved stability and experimental utility for microwave breast imaging.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
用于乳腺微波传感壳基模型的组织模拟材料
在临床应用之前,需要用乳房模型来测试和评估微波乳房成像系统。基于壳体的乳房模型用途广泛、可重现性好、成本低、稳定性高,并且能够模拟乳房的形态和介电特性。在过去的工作中,这些模型的外壳是用三维可打印塑料制造的,但低介电常数塑料限制了模型的介电精度。此外,这些基于外壳的模型中的液体容易产生气泡,可能会带来不良的微波散射。这项工作研究了新的组织仿真材料,以应对这些挑战。在 0.4-9.0 GHz 范围内,用石墨、碳黑和树脂混合物取代了低容性 3D 打印塑料丝,以模拟皮肤特性。甘油和 Triton X-100 被二甘醇丁醚 (DGBE) 溶液取代,以模拟脂肪组织和纤维腺组织的特性。与三维打印塑料相比,树脂基材料更接近于模拟活体组织样本的特性。与甘油和 Triton X-100 溶液相比,DGBE 溶液具有更好的介电性能。与甘油和 Triton X-100 溶液相比,DGBE 溶液具有粘度低、不易产生气泡、短期稳定性和温度稳定性更好以及长期稳定性更强等优点,有利于这些材料的重复使用。这项工作中研究的材料可用于制作介电精确度更高的乳房模型,其稳定性和微波乳房成像的实验实用性都有所提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.80
自引率
9.40%
发文量
58
期刊最新文献
Front Cover Table of Contents IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information Models of Melanoma Growth for Assessment of Microwave-Based Diagnostic Tools
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1