Comprehensive analysis of antibiotic and heavy metal resistance, and virulence factors in Aeromonas veronii CTe-01: Implications for global antimicrobial resistance

IF 3.7 3区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES Journal of King Saud University - Science Pub Date : 2024-08-19 DOI:10.1016/j.jksus.2024.103402

{"title":"Comprehensive analysis of antibiotic and heavy metal resistance, and virulence factors in Aeromonas veronii CTe-01: Implications for global antimicrobial resistance","authors":"","doi":"10.1016/j.jksus.2024.103402","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to characterize <em>Aeromonas veronii</em> CTe-01 focusing on its resistance to heavy metal and antibiotics.</p></div><div><h3>Methods</h3><p><em>A. veronii</em> CTe-01 was characterized using standard microbiological and molecular techniques. Antibiotic susceptibility and heavy metal resistance were tested per standard protocols. Genomic analysis, including plasmid characterization, was conducted in silico.</p></div><div><h3>Results</h3><p><em>A. veronii</em> CTe-01 showed resistance to various heavy metals and antibiotics. Multiple resistance genes were identified, including those for beta-lactamases, heavy metal resistance, and type III secretion system components. The bacterium carries a 9 kb plasmid with <em>repA/repB</em> replication genes, <em>parA/parB</em> partitioning genes, and a type II toxin-antitoxin system for stability.</p></div><div><h3>Conclusions</h3><p><em>A. veronii</em> CTe-01 is a genetic reservoir for antibiotic resistance, heavy metal resistance genes, and virulence factors. The study offers insights into its dual role as a pathogen and heavy metal remediator in aquatic environments.</p></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1018364724003148/pdfft?md5=e83ed514960dcc28bededa2efdae41c0&pid=1-s2.0-S1018364724003148-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of King Saud University - Science","FirstCategoryId":"103","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1018364724003148","RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives

This study aimed to characterize Aeromonas veronii CTe-01 focusing on its resistance to heavy metal and antibiotics.

Methods

A. veronii CTe-01 was characterized using standard microbiological and molecular techniques. Antibiotic susceptibility and heavy metal resistance were tested per standard protocols. Genomic analysis, including plasmid characterization, was conducted in silico.

Results

A. veronii CTe-01 showed resistance to various heavy metals and antibiotics. Multiple resistance genes were identified, including those for beta-lactamases, heavy metal resistance, and type III secretion system components. The bacterium carries a 9 kb plasmid with repA/repB replication genes, parA/parB partitioning genes, and a type II toxin-antitoxin system for stability.

Conclusions

A. veronii CTe-01 is a genetic reservoir for antibiotic resistance, heavy metal resistance genes, and virulence factors. The study offers insights into its dual role as a pathogen and heavy metal remediator in aquatic environments.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

全面分析蚯蚓气单胞菌 CTe-01 的抗生素和重金属耐药性及毒力因子：对全球抗菌药耐药性的影响

方法使用标准微生物学和分子技术对维龙气单胞菌 CTe-01 进行鉴定。按照标准方案对抗生素敏感性和重金属抗性进行了测试。结果A. veronii CTe-01 显示出对各种重金属和抗生素的抗性。发现了多种抗性基因，包括β-内酰胺酶基因、重金属抗性基因和 III 型分泌系统元件基因。结论A. veronii CTe-01 是抗生素抗性、重金属抗性基因和毒力因子的基因库。这项研究有助于深入了解它在水生环境中作为病原体和重金属清除剂的双重角色。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of King Saud University - Science Multidisciplinary-Multidisciplinary

CiteScore

7.20

自引率

2.60%

发文量

642

审稿时长

49 days

期刊介绍： Journal of King Saud University – Science is an official refereed publication of King Saud University and the publishing services is provided by Elsevier. It publishes peer-reviewed research articles in the fields of physics, astronomy, mathematics, statistics, chemistry, biochemistry, earth sciences, life and environmental sciences on the basis of scientific originality and interdisciplinary interest. It is devoted primarily to research papers but short communications, reviews and book reviews are also included. The editorial board and associated editors, composed of prominent scientists from around the world, are representative of the disciplines covered by the journal.