Lorenz Leitner, Laila Schneidewind, Gernot Bonkat, Fabian P Stangl, Jennifer Kranz
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引用次数: 0
Abstract
Urinary tract infections (UTIs) are frequently associated with lower urinary tract dysfunction (LUTD). Urodynamic investigation (UDI) is the gold standard for assessing LUTD, but its value in identifying UTI risk factors remains underexplored. Studies have shown high rates of storage and voiding dysfunction in patients with recurrent UTIs, suggesting a causal link between LUTD and UTIs. Specific UDI findings, such as low bladder capacity, high detrusor pressures, and detrusor overactivity, have been associated with greater UTI risk, especially in kidney transplant recipients and infants. However, the current evidence is limited by the lack of control groups and therapeutic interventions, making it difficult to draw definitive conclusions. Further well-designed studies are needed to determine if UDI-guided therapies can improve UTI management outcomes. PATIENT SUMMARY: Urinary infections are often linked to problems with the lower urinary tract. Tests that measure lower urinary tract function can help in identifying these issues. More research is needed to see if treating bladder problems can prevent urinary infections.
尿路感染(UTI)常常与下尿路功能障碍(LUTD)有关。尿动力学检查(UDI)是评估下尿路功能障碍的黄金标准,但其在确定 UTI 风险因素方面的价值仍未得到充分开发。研究显示,复发性尿毒症患者的储尿和排尿功能障碍发生率很高,这表明 LUTD 与尿毒症之间存在因果关系。特定的 UDI 发现,如膀胱容量小、逼尿肌压力高和逼尿肌过度活动,与 UTI 风险增大有关,特别是在肾移植受者和婴儿中。然而,由于缺乏对照组和治疗干预措施,目前的证据还很有限,因此很难得出明确的结论。要确定 UDI 指导疗法是否能改善 UTI 的治疗效果,还需要进一步开展精心设计的研究。患者摘要:尿路感染通常与下尿路问题有关。测量下尿路功能的检查有助于发现这些问题。治疗膀胱问题是否能预防泌尿感染还需要更多的研究。
期刊介绍:
ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.