Video capsule endoscopy findings in dogs with chronic enteropathy and in healthy dogs

IF 2.1 2区 农林科学 Q1 VETERINARY SCIENCES Journal of Veterinary Internal Medicine Pub Date : 2024-08-24 DOI:10.1111/jvim.17168
Johanna Holmberg, Ingrid Ljungvall, Lena Pelander, Alice Defarges, Jenny Stiller, Jessica Ingman, Caroline Harlos, Thomas Spillmann, Jens Häggström
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Abstract

Background

Video capsule endoscopy is a noninvasive technique for evaluation of the gastrointestinal tract.

Objective

To investigate the safety of using the video capsule ALICAM in dogs with chronic enteropathy (CE) >10 kg, and to compare macroscopic gastrointestinal morphology between CE dogs and healthy controls (HC).

Animals

Fifteen CE dogs and 15 similarly breed, age and body weight matched HC.

Methods

All dogs underwent a clinical work up including blood analyses, fecal samples, abdominal ultrasonographic examination, and blood pressure measurement. The dogs were withheld from food for 16 hours before and 8 hours after they PO received an ALICAM. All recordings were quality assessed, and blindly evaluated by 2 trained observers.

Results

The median age of CE dogs and HC was 3.3 (interquartile range [IQR] 2.5-5.9) years and 4.7 (IQR 3.3-5.6) years, respectively. The median body weight in the CE dogs and HC was 25.9 (IQR 20.6-30.9) kg, and 29 (IQR 16.2-30.5) kg, respectively. Complete recordings of the gastrointestinal tract were obtained from all dogs without complications. No significant differences were found between groups regarding number of abnormalities such as irregular mucosa, erythema, nonbleeding erosions, bleeding erosions, and dilated lacteals, as well as severity and extent of the abnormalities.

Conclusions and Clinical Importance

The use of ALICAM for evaluation of the gastrointestinal tract in CE dogs and HC seems safe and feasible regarding gastrointestinal transit and macroscopic morphology assessment in dogs >10 kg. Abnormalities were found in similar proportions in CE dogs and HC.

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慢性肠病犬和健康犬的视频胶囊内窥镜检查结果。
背景:视频胶囊内镜是一种评估胃肠道的无创技术:视频胶囊内镜是一种评估胃肠道的无创技术:研究在体重大于 10 千克的慢性肠病(CE)犬中使用视频胶囊 ALICAM 的安全性,并比较 CE 犬和健康对照组(HC)的胃肠道宏观形态:动物:15 只 CE 狗和 15 只品种、年龄和体重相近的健康对照组(HC):方法:所有犬均接受临床检查,包括血液分析、粪便样本、腹部超声波检查和血压测量。在注射 ALICAM 前 16 小时和注射后 8 小时内,狗不能进食。所有记录都经过质量评估,并由两名训练有素的观察员进行盲评:CE犬和HC犬的中位年龄分别为3.3(四分位距[IQR] 2.5-5.9)岁和4.7(IQR 3.3-5.6)岁。CE犬和HC犬的体重中位数分别为25.9(IQR 20.6-30.9)千克和29(IQR 16.2-30.5)千克。所有无并发症的犬均获得了完整的胃肠道记录。在粘膜不规则、红斑、非出血糜烂、出血糜烂和乳管扩张等异常的数量以及异常的严重程度和范围方面,各组之间没有发现明显差异:使用 ALICAM 评估 CE 犬和 HC 的胃肠道似乎安全可行,可对体重大于 10 千克的犬进行胃肠道转运和宏观形态评估。CE犬和HC犬发现异常的比例相似。
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来源期刊
CiteScore
4.50
自引率
11.50%
发文量
243
审稿时长
22 weeks
期刊介绍: The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
期刊最新文献
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