Developmental genetics of cuticular micro- and nano-structures in insects

Abstract

Insect cuticle exhibits a wide array of micro- and nano-structures in terms of size, form, and function. However, the investigation of cellular mechanisms of morphogenesis has centered around a small number of structure types and organisms. The recent expansion of the taxa studied, and subsequent discoveries prompt us to revisit well-known models, like the one for bristle morphogenesis. In addition, common themes are emerging in the morphogenesis of cuticular structures, such as the polyploidy of precursor cells, the role of pigments and cuticular proteins in controlling chitin deposition in space and time, and the role of the apical extracellular matrix in defining the shape of the developing structure. Understanding how these structures are synthesized in biological systems holds promise for bioinspired design.