[Risk factors for postoperative mortality within 1 year in more than 90-year-old super advanced age patients with hip fractures].

Sha-Sha Chai, Jun-Wei Hu, Lei Han
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Abstract

Objective: To investigate the 1 year mortality after hip fractures in super advanced age patients and summarize the death associated risk factors in order to provide basis for targeted intervention countermeasures.

Methods: The clinical data of 332 super advanced age patients with femoral neck or intertrochanteric fractures treated by hip replacement or intramedullary femoral nail fixation from January 2015 to January 2023 were retrospectively analyzed. There were 128 males and 204 females with the mean age of (92.2±2.5) years ranging from 90 to 103 years old. Among them, 92 cases died within 1 year after surgery. Correlation with the occurrence of death on age, gender, body mass index, fracture type, treatment method, timing of operation, preoperative hemoglobin and serum albumin level, operation time, combined medical diseases, pre-injury mobilityand American Society of Anesthesiology(ASA) classification were analyzed. The risk factors of death within 1 year after operation were screened by univariate analysis. The results were entered into the multivariate Logistic regression analysis, screening the high risk factors for 1 year mortality after hip fractures.

Results: The mortality of super advanced age patients with hip fracture within 1 year after surgery accounted for 27.7%(92/332). Univariate analysis showed high body mass index, long interval from injury to surgery, low preoperative serum albumin levels, inability to walk independently before injury, accompanied by heart failure, pulmonary infection, obstructive pulmonary disease, stroke, and a higher proportion of ASA grades Ⅲ-Ⅳ. Multivariate Logistic regression analysis showed preoperative serum albumin below 30g g·L-1[OR=2.973, 95%CI(2.461, 5.344), P=0.039], inability to walk independently before injury [OR=3.519, 95%CI(2.224, 5.413), P=0.018], heart function grade C-D[OR=4.213, 95%CI(2.952, 6.99), P=0.021], pulmonary infection[OR=3.927, 95%CI(2.187, 7.731), P=0.016] and ASA Ⅲ-Ⅳ[OR=5.124, 95%CI(3.092, 8.235), P=0.032] were the independent risk factors for death within 1 year in super advanced age patients with hip fractures.

Conclusion: Preoperative serum albumin below 30g.L-1, poor preinjury activity, heart function grade C-D, pulmonary infection, and ASA grade Ⅲ-Ⅳ are independent risk factors for postoperative mortality in super advanced age patients with hip fractures.

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[90岁以上超高龄髋部骨折患者术后1年内死亡的风险因素]。
摘要调查超高龄患者髋部骨折后1年的死亡率,总结与死亡相关的危险因素,为采取针对性干预对策提供依据:回顾性分析2015年1月至2023年1月期间332例超高龄股骨颈或转子间骨折患者接受髋关节置换术或股骨髓内钉固定术治疗的临床资料。男性 128 例,女性 204 例,平均年龄为(92.2±2.5)岁,从 90 岁到 103 岁不等。其中 92 例在术后 1 年内死亡。分析了死亡发生与年龄、性别、体重指数、骨折类型、治疗方法、手术时间、术前血红蛋白和血清白蛋白水平、手术时间、合并内科疾病、伤前活动能力和美国麻醉学会(ASA)分级的相关性。通过单变量分析筛选出术后 1 年内死亡的风险因素。结果显示,髋部骨折的超高龄患者术后 1 年内的死亡率较高:结果:超高龄髋部骨折患者术后 1 年内的死亡率为 27.7%(92/332)。单变量分析显示,患者体重指数高、受伤至手术时间间隔长、术前血清白蛋白水平低、受伤前不能独立行走、伴有心衰、肺部感染、阻塞性肺疾病、脑卒中、ASA Ⅲ-Ⅳ级比例较高。多变量 Logistic 回归分析显示,术前血清白蛋白低于 30g g-L-1[OR=2.973,95%CI(2.461,5.344),P=0.039],伤前不能独立行走[OR=3.519,95%CI(2.224,5.413),P=0.018],心功能 C-D 级[OR=4.213,95%CI(2.952,6.99),P=0.021]、肺部感染[OR=3.927,95%CI(2.187,7.731),P=0.016]和ASA Ⅲ-Ⅳ级[OR=5.124,95%CI(3.092,8.235),P=0.032]是超高龄髋部骨折患者1年内死亡的独立危险因素:结论:术前血清白蛋白低于30g.L-1、伤前活动能力差、心功能C-D级、肺部感染和ASAⅢ-Ⅳ级是超高龄髋部骨折患者术后死亡的独立危险因素。
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