Sevara M. Allabergenova , Fazliddin A. Zulpanov , Nasiba B. Pirnazarova , Ubaydulla M. Yakubov , Kosim O. Zokhidov , Sirojiddin S. Abdullayev , Azimjon А. Mamadrakhimov , Jamshid M. Ashurov , Akmaljon G. Tojiboev , Burkhon Zh. Elmuradov
{"title":"Design and one-pot synthesis of 2H(methyl)-3-alkyl-4-oxo-3,4-dihydroquinazoline-6-sulfonamides","authors":"Sevara M. Allabergenova , Fazliddin A. Zulpanov , Nasiba B. Pirnazarova , Ubaydulla M. Yakubov , Kosim O. Zokhidov , Sirojiddin S. Abdullayev , Azimjon А. Mamadrakhimov , Jamshid M. Ashurov , Akmaljon G. Tojiboev , Burkhon Zh. Elmuradov","doi":"10.1016/j.cdc.2024.101160","DOIUrl":null,"url":null,"abstract":"<div><p>2H(Methyl)-3-alkylquinazolin-4(3H)-ones were synthesized by reactions of 2H(methyl)quinazolin-4(3H)-ones with alkyl halides. The obtained 2H(methyl)-3-alkylquinazolin-4(3H)-ones were subjected to one-pot synthesis in the presence of chlorosulfonic acid and ammonia, primary sulfonamides among bicyclic quinazolines were synthesized and were characterized by <sup>1</sup>H NMR, <sup>13</sup>C NMR, IR and mass spectral data. The crystal structure of 2-methyl-3‑butyl‑4-oxo-3,4-dihydroquinazoline-6-sulfonamide was determined by the single-crystal X-ray diffraction method at 293 K.</p></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"53 ","pages":"Article 101160"},"PeriodicalIF":2.2180,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Data Collections","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S240583002400048X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Chemistry","Score":null,"Total":0}
引用次数: 0
Abstract
2H(Methyl)-3-alkylquinazolin-4(3H)-ones were synthesized by reactions of 2H(methyl)quinazolin-4(3H)-ones with alkyl halides. The obtained 2H(methyl)-3-alkylquinazolin-4(3H)-ones were subjected to one-pot synthesis in the presence of chlorosulfonic acid and ammonia, primary sulfonamides among bicyclic quinazolines were synthesized and were characterized by 1H NMR, 13C NMR, IR and mass spectral data. The crystal structure of 2-methyl-3‑butyl‑4-oxo-3,4-dihydroquinazoline-6-sulfonamide was determined by the single-crystal X-ray diffraction method at 293 K.
期刊介绍：
Chemical Data Collections (CDC) provides a publication outlet for the increasing need to make research material and data easy to share and re-use. Publication of research data with CDC will allow scientists to: -Make their data easy to find and access -Benefit from the fast publication process -Contribute to proper data citation and attribution -Publish their intermediate and null/negative results -Receive recognition for the work that does not fit traditional article format. The research data will be published as ''data articles'' that support fast and easy submission and quick peer-review processes. Data articles introduced by CDC are short self-contained publications about research materials and data. They must provide the scientific context of the described work and contain the following elements: a title, list of authors (plus affiliations), abstract, keywords, graphical abstract, metadata table, main text and at least three references. The journal welcomes submissions focusing on (but not limited to) the following categories of research output: spectral data, syntheses, crystallographic data, computational simulations, molecular dynamics and models, physicochemical data, etc.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
