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The impact of an extract from the Clerodendrum serratum plant on steel corrosion in a sulfuric acid solution was examined using weight loss analysis and electrochemical impedance spectroscopy (EIS). This research delves into the synergistic corrosion inhibition efficiency of Clerodendrum serratum in the presence of KCl. This extract contains Apigenin, Hispidulin, 7- hydroxyflavanone, Oleanolic acid, β-sitosterol, Campesterol, Stigmasterol, Ursolic acid, Serratin, Spinasterol, Queretaroic acid etc. The anti-corrosive properties of this extract are primarily attributed to the presence of numerous bonds and heteroatoms in its phytochemical composition. Instrumentation such as UV analysis provides detailed insights into molecular interactions, aiding in the understanding of inhibitive mechanisms. The effectiveness of corrosion inhibition improves as the concentration of plant extract is raised up to 3000 ppm. Utilizing Potentiodynamic polarization (PDP) examination, achieving 88.6 % efficiency without KCl and 93.05 % in the presence of KCl demonstrates a comprehensive approach for improving protective characteristics in practical applications.

A total of Twenty two (22) derivatives of benzohydrazide bearing Schiff base have been synthesized, characterized through ¹HNMR, ¹³C NMR and screened against cholinesterase inhibitory potentials. All the adducts (1–22) showed varying degree of cholinesterase inhibitory potential IC₅₀ ranging between 13.23 ± 0.02 to 59.09 ± 1.22 µM against acetylcholinesterase, with IC₅₀ values ranging from 23.55 ± 0.32 to 61.55 ± 0.58 µM against butyrylcholinesterase. Among the series analogs 1, 3, 8, 12, 14, 15, 17, 18 and 22 with IC₅₀ values 20.05 ± 0.13, 17.32 ± 0.15, 14.32 ± 0.97, 23.33 ± 0.56, 18.02 ± 0.09, 19.05 ± 0.13, 15.11 ± 0.23, 13.23 ± 0.02, and 22.57 ± 0.09 µM respectively showed excellent inhibitory potential against acetylcholinesterase and with IC₅₀ values 31.46 ± 0.98, 26.06 ± 0.08, 25.33 ± 1.49, 30.12 ± 0.78, 28.11 ± 0.5, 29.33 ± 0.19, 25.37 ± 0.47, 23.55 ± 0.32 and 33.12 ± 0.78 against butylcholinesterase as compared to the standard Galanthamine. All other analogs showed moderate inhibitory potential. A structure-activity relationship has been established for all compounds. Through molecular docking studies, the interactions between compounds with the enzyme active sites were confirmed.

This work investigates the possibility of using expired Febuxostat, a drug mainly used to treat gout, as a corrosion inhibitor for steel in solutions containing Hydrochloric acid (HCl), which is an unusual but potentially successful approach. The goal of this research is to recycle pharmaceutical waste for useful purposes while also meeting the requirement for sustainable and economical corrosion mitigation techniques. The study includes various analytical techniques, like SEM, weight loss, electrochemical techniques, and density functional theory (DFT) to evaluate the efficacy of expired febuxostat as a corrosion inhibitor for steel in 0.5 M HCl solution. The EIS and PDP curve results showed a direct correlation between the concentration of Febuxostat and the inhibition efficiency. The active center of the electrode surface is blocked by the drug molecules, which reduces the corrosion mechanism. The data from the Langmuir adsorption isotherm validates a physiochemical process. Moreover, SEM investigations show that steel has a smoother surface. The adsorption behavior of Febuxostat molecules on the steel surface is investigated, providing insight into the chemical mechanisms underlying the inhibitory effect.

The present study explores the green synthesis of silver nanoparticles (AgNPs) using Urginea indica (Roxb.) Kunth bulb extract, emphasizes its eco-friendly and cost-effective nature. Characterization techniques, including UV-Vis Spectrophotometer, FTIR spectroscopy, XRD, and TEM, confirmed the successful synthesis, revealing spherical AgNPs with a size range of 9-30 nm. In antimicrobial activity, these nanoparticles exhibited significant growth inhibition activity against bacteria like Pseudomonas aeruginosa (22.66 ± 3.05 mm), S. aureus (15.33 ± 0.57 mm), E. coli (14 ± 1 mm), and fungi like Candida albicans (35.6 mm), with a notable zone of inhibition. The phytochemical analysis of the bulb extract reveals that it has various bioactive compounds, such as phenols, flavonoids, saponins, glycosides, terpenoids, and steroids, likely contributing to the reduction and stabilization of AgNPs. The green synthesis process was used for its simplicity, cleanliness, and lack of pollutants. The study shows how natural resources can be used to develop nanoparticles to fight against increasing drug resistance problems.

A new series of amides of pyridin-3-yl)imidazo[2,1-b][1,3,4]thiadiazoles (13a-j) have been developed and confirmed by ¹HNMR, ¹³CNMR and mass spectral data. Further, in the vitro anticancer activity of newly prepared compounds 13a-j was examined against four human cancer cell lines including MCF-7 & MDA MB-231 (human breast cancer), A549 (human lung cancer) and DU-145 (human prostate cancer) by employing the MTT assay, and using etoposide as a standard reference. These results indicated that the most of the derivatives displayed excellent to moderate anticancer activity. Among the five compounds 13a, 13b, 13c, 13d and 13e demonstrated remarkable activity as standard. One of the compounds 13a displayed excellent activity.

A new library of sulfonamide derivatives of benzothiazol-quinoline-pyrazole (11a-j) were design and synthesized and their chemical structures were confirmed by ¹HNMR, ¹³CNMR and mass spectral data. Further, all derivatives were evaluated for their preliminary anticancer applications against a panel of four human cancer cell lines such as prostate cancer cell (PC3), lung cancer cell (A549), breast cancer cell (MCF-7) and prostate cancer cell (DU-145) by using of MTT method and the obtained results were expressed with IC₅₀ µM. Most of the screened compounds were displayed moderate to good activity and etoposide utilized as positive control. Among them, five compounds 11a, 11b, 11 h, 11i and 11j were revealed more potent activities.

This paper investigates the mixed convective pour of a nanofluid through warmth as well as accumulation transport induced by the vertical rotation of a permeable truncated cone. The study considers convective-type thermal boundary conditions and zero nanoparticle mass flux conditions. The effects of thermophoresis and Brownian motion have been integrated into the present nanofluid model. To transform the coupled non-linear border line sheet equations into dimensionless partial differential equations, a set of non-similarity transformations is introduced. The ensuing PDEs are then numerically figured out using a Spectral collocation method in conjunction with the local linearization technique. To authenticate the numerical technique, the obtained outcomes are in contrast to with established findings in a specific case. The manipulate of a variety of corporeal constraints inactive on the tangential and swirl velocities of the nanofluid, as well as warmth, hard volume fraction, as well as exterior drag, warmth, as well as accumulation transport characteristics, are discussed.

A polemic is given regarding the volumetric properties reported by Ramadevi and coworkers for binary systems containing either ethylene glycol or glycerol mixed with either hexane or cyclohexane or benzene. The six binary systems studied by the authors are not completely miscible, and separate into a polyhydroxy alcohol-rich liquid phase and an alkane-rich liquid phase.