Case Report: Campylobacter Bacteremia in India.

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH American Journal of Tropical Medicine and Hygiene Pub Date : 2024-08-27 DOI:10.4269/ajtmh.24-0193
Srived Meda, Padmaja Shenoy, Gauri Kumar, Muralidhar Varma, Chiranjay Mukhopadhyay, Vandana Kalwaje Eshwara
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Abstract

Gastroenteritis is the frequent clinical manifestation of infection by Campylobacter spp., whereas invasive infections such as bacteremia are less commonly reported. We report 12 cases of Campylobacter bacteremia from a tertiary-care hospital in India and describe their relatively unique characteristics compared with the previously published reports. These cases were detected after the introduction of new blood culture media. The most common symptoms were fever (eight cases, 67%), abdominal pain (six cases, 50%), and vomiting (four cases, 33%), whereas only two cases (17%) had diarrhea. Chronic liver disease was the common underlying condition affecting eight patients (75%). The median Child-Pugh and Model for End-Stage Liver Disease scores were 9 (interquartile range: 7-9.5) and 20 (interquartile range: 15-23) respectively. Campylobacter jejuni was isolated in six patients (50%), two of whom had preceding diarrhea and one patient who had culture evidence of C. jejuni in ascitic fluid. The in-hospital mortality was 8%, but this was due to subsequent Escherichia coli sepsis.

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病例报告:印度弯曲杆菌菌血症。
肠胃炎是弯曲杆菌属感染的常见临床表现,而菌血症等侵袭性感染则较少报道。我们报告了来自印度一家三级医院的 12 例弯曲杆菌菌血症病例,并描述了这些病例与之前发表的报告相比相对独特的特征。这些病例是在引入新的血液培养基后发现的。最常见的症状是发热(8 例,占 67%)、腹痛(6 例,占 50%)和呕吐(4 例,占 33%),只有 2 例(占 17%)有腹泻。慢性肝病是常见的基础疾病,影响了八名患者(75%)。Child-Pugh评分和终末期肝病模型评分的中位数分别为9(四分位数间距:7-9.5)和20(四分位数间距:15-23)。六名患者(50%)分离出空肠弯曲菌,其中两名患者之前曾腹泻,一名患者腹水中有空肠弯曲菌培养证据。院内死亡率为 8%,但这是由于随后发生的大肠埃希菌败血症所致。
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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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