A diffusion model multi-scale feature fusion network for imbalanced medical image classification research

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computer methods and programs in biomedicine Pub Date : 2024-08-23 DOI:10.1016/j.cmpb.2024.108384
Zipiao Zhu , Yang Liu , Chang-An Yuan , Xiao Qin , Feng Yang
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Abstract

Background and objective

Medicine image classification are important methods of traditional medical image analysis, but the trainable data in medical image classification is highly imbalanced and the accuracy of medical image classification models is low. In view of the above two common problems in medical image classification. This study aims to: (i) effectively solve the problem of poor training effect caused by the imbalance of class imbalanced data sets. (ii) propose a network framework suitable for improving medical image classification results, which needs to be superior to existing methods.

Methods

In this paper, we put in the diffusion model multi-scale feature fusion network (DMSFF), which mainly uses the diffusion generation model to overcome imbalanced classes (DMOIC) on highly imbalanced medical image datasets. At the same time, it is processed according to the cropped image augmentation strategy through cropping (IASTC). Based on this, we use the new dataset to design a multi-scale feature fusion network (MSFF) that can fully utilize multiple hierarchical features. The DMSFF network can effectively solve the problems of small and imbalanced samples and low accuracy in medical image classification.

Results

We evaluated the performance of the DMSFF network on highly imbalanced medical image classification datasets APTOS2019 and ISIC2018. Compared with other classification models, our proposed DMSFF network achieved significant improvements in classification accuracy and F1 score on two datasets, reaching 0.872, 0.731, and 0.906, 0.836, respectively.

Conclusions

Our newly proposed DMSFF architecture outperforms existing methods on two datasets, and verifies the effectiveness of generative model inverse balance for imbalance class datasets and feature enhancement by multi-scale feature fusion. Further, the method can be applied to other class imbalanced data sets where the results will be improved.

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用于不平衡医学图像分类研究的扩散模型多尺度特征融合网络
背景与目的医学图像分类是传统医学图像分析的重要方法,但医学图像分类中的可训练数据极不平衡,医学图像分类模型的准确率较低。鉴于以上两个医学图像分类中的常见问题。本研究旨在:(i) 有效解决因类不平衡数据集不平衡而导致的训练效果差的问题。(方法本文提出了扩散模型多尺度特征融合网络(DMSFF),主要利用扩散生成模型克服高度不平衡医学图像数据集上的类不平衡(DMOIC)。同时,它还根据裁剪图像增强策略(IASTC)进行处理。在此基础上,我们利用新数据集设计了一种能充分利用多种分层特征的多尺度特征融合网络(MSFF)。结果我们在高度不平衡的医学图像分类数据集 APTOS2019 和 ISIC2018 上评估了 DMSFF 网络的性能。与其他分类模型相比,我们提出的 DMSFF 网络在两个数据集上的分类准确率和 F1 分数都有显著提高,分别达到了 0.872、0.731 和 0.906、0.836。结论我们新提出的 DMSFF 架构在两个数据集上的表现优于现有方法,并验证了不平衡类数据集的生成模型逆平衡和多尺度特征融合的特征增强的有效性。此外,该方法还可应用于其他类不平衡数据集,其结果将得到改善。
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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