The Botulinum Toxin Innovation: From Powder to Liquid.

IF 2.5 3区 医学 Q2 DERMATOLOGY Dermatologic Surgery Pub Date : 2024-09-01 Epub Date: 2024-07-31 DOI:10.1097/DSS.0000000000004358
Wooshun Lee, Hyun Ho Jung
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引用次数: 0

Abstract

Background: Botulinum toxin (BoNT) has evolved as a popular treatment for various medical and aesthetic conditions since the 1980s. The emergence of new liquid formulation BoNT products in the industry highlights the need to evaluate the value and advantages of these modern formulations.

Objective: The aim of this review was to assess and compare the expected difference in practice between liquid and powder formulation BoNT products.

Paitents and methods/materials: This article involves a review of pertinent guidelines, product information from manufacturers, available database for safety reports, and survey results.

Results: Guidelines and safety reports have pointed out potential risks in the reconstitution process, while medication preparation steps are simplified in liquid formulation.

Conclusion: The shift toward ready-to-use liquid products can mitigate risks related with reconstitution errors and potentially enhancing patient care by saving time and cost associated with medication preparation.

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肉毒杆菌毒素创新:从粉末到液体
背景:自 20 世纪 80 年代以来,肉毒杆菌毒素(BoNT)逐渐成为治疗各种医疗和美容疾病的流行疗法。随着新型液体配方 BoNT 产品在业界的出现,评估这些现代配方的价值和优势的必要性凸显出来:本综述旨在评估和比较液体和粉末配方 BoNT 产品在实践中的预期差异:本文回顾了相关指南、制造商提供的产品信息、现有的安全报告数据库以及调查结果:结果:指南和安全报告指出了复溶过程中的潜在风险,而液体制剂则简化了药物制备步骤:结论:向即用型液体产品的转变可以降低与复溶错误有关的风险,并通过节省药物配制的时间和成本来改善对患者的护理。
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来源期刊
Dermatologic Surgery
Dermatologic Surgery 医学-皮肤病学
CiteScore
3.10
自引率
16.70%
发文量
547
期刊介绍: Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.
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