Effect of omega-3 fatty acids supplementation on inflammatory markers following exercise-induced muscle damage: Systematic review and meta-analysis of randomized controlled trials

IF 0.5 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Nutrition Clinique et Metabolisme Pub Date : 2024-08-09 DOI:10.1016/j.nupar.2024.04.006
Yasaman Nasir, Mohammad Hossein Rahimi
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Abstract

Background

Omega-3 fatty acids supplementation may protect against exercise-induced muscle damage (EIMD) through its anti-inflammatory properties. The purpose of the present meta-analysis was to evaluate the effects of omega-3 fatty acid supplementation on inflammatory markers following EIMD in trained and untrained individuals.

Methods

Medline, Scopus, and Google Scholar databases were systematically searched up to April 2023. The Cochrane Collaboration tool was used to assess the risk of bias and evaluate the quality of the studies.

Results

Omega-3 supplementation significantly reduced interleukin (IL) 6, tumor necrosis factor (TNF)-ɑ, and C-reactive protein (CRP) concentrations.

Conclusion

The current meta-analysis indicated the efficacy of omega-3 in reducing the serum levels of inflammatory markers in healthy individuals, overall, and in subgroup analysis. Thus, omega-3 may be a priority EIMD recovery agent for interventions.

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补充欧米伽-3 脂肪酸对运动诱发肌肉损伤后炎症指标的影响:随机对照试验的系统回顾和荟萃分析
背景补充欧米伽-3 脂肪酸可通过其抗炎特性防止运动诱发的肌肉损伤(EIMD)。本荟萃分析旨在评估补充欧米伽-3 脂肪酸对受过训练和未受过训练的人发生 EIMD 后炎症指标的影响。结果补充欧米伽-3能显著降低白细胞介素(IL)6、肿瘤坏死因子(TNF)-ɑ和C反应蛋白(CRP)的浓度。结论目前的荟萃分析表明,欧米伽-3能有效降低健康人血清中炎症标志物的水平,无论是总体还是亚组分析。因此,欧米伽-3 可能是一种优先干预的 EIMD 恢复剂。
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来源期刊
Nutrition Clinique et Metabolisme
Nutrition Clinique et Metabolisme 医学-内分泌学与代谢
CiteScore
0.80
自引率
16.70%
发文量
216
审稿时长
78 days
期刊介绍: Nutrition Clinique et Métabolisme is the journal of the French-speaking Society of Enteral and Parenteral Nutrition. Associating clinicians, biologists, pharmacists, and fundamentalists, the articles presented in the journal concern man and animals, and deal with organs and cells. The goal is a better understanding of the effects of artificial nutrition and human metabolism. Original articles, general reviews, update articles, technical notes and communications are published, as well as editorials and case reports.
期刊最新文献
Editorial board Issue contents Applicability of Global Leadership Initiative on Malnutrition (GLIM) criteria in nutrition risk screening for patients over 60 years old with digestive system tumors – A retrospective study Effect of omega-3 fatty acids supplementation on inflammatory markers following exercise-induced muscle damage: Systematic review and meta-analysis of randomized controlled trials Associations between Diet Inflammatory Index Scores and nutritional status in chronic kidney disease patients
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