BGformer: An improved Informer model to enhance blood glucose prediction

IF 4 2区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Journal of Biomedical Informatics Pub Date : 2024-08-26 DOI:10.1016/j.jbi.2024.104715
Yuewei Xue, Shaopeng Guan, Wanhai Jia
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Abstract

Accurately predicting blood glucose levels is crucial in diabetes management to mitigate patients’ risk of complications. However, blood glucose values exhibit instability, and existing prediction methods often struggle to capture their volatile nature, leading to inaccurate trend forecasts. To address these challenges, we propose a novel blood glucose level prediction model based on the Informer architecture: BGformer. Our model introduces a feature enhancement module and a microscale overlapping concerns mechanism. The feature enhancement module integrates periodic and trend feature extractors, enhancing the model’s ability to capture relevant information from the data. By extending the feature extraction capacity of time series data, it provides richer feature representations for analysis. Meanwhile, the microscale overlapping concerns mechanism adopts a window-based strategy, computing attention scores only within specific windows. This approach reduces computational complexity while enhancing the model’s capacity to capture local temporal dependencies. Furthermore, we introduce a dual attention enhancement module to augment the model’s expressive capability. Through prediction experiments on blood glucose values from sixteen diabetic patients, our model outperformed eight benchmark models in terms of both MAE and RMSE metrics for future 60-minute and 90-minute predictions. Our proposed scheme significantly improves the model’s dependency-capturing ability, resulting in more accurate blood glucose level predictions.

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BGformer:改进的 Informer 模型可提高血糖预测能力
准确预测血糖水平对糖尿病管理至关重要,可降低患者出现并发症的风险。然而,血糖值具有不稳定性,现有的预测方法往往难以捕捉其波动性,导致趋势预测不准确。为了应对这些挑战,我们提出了一种基于 Informer 架构的新型血糖水平预测模型:BGformer。我们的模型引入了特征增强模块和微尺度重叠关注机制。特征增强模块集成了周期和趋势特征提取器,增强了模型从数据中捕捉相关信息的能力。通过扩展时间序列数据的特征提取能力,它为分析提供了更丰富的特征表示。同时,微尺度重叠关注机制采用基于窗口的策略,只计算特定窗口内的关注分数。这种方法既降低了计算复杂度,又增强了模型捕捉局部时间依赖性的能力。此外,我们还引入了双重注意力增强模块,以提高模型的表达能力。通过对 16 名糖尿病患者的血糖值进行预测实验,我们的模型在未来 60 分钟和 90 分钟预测的 MAE 和 RMSE 指标方面均优于 8 个基准模型。我们提出的方案大大提高了模型的依赖捕捉能力,使血糖水平预测更加准确。
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来源期刊
Journal of Biomedical Informatics
Journal of Biomedical Informatics 医学-计算机:跨学科应用
CiteScore
8.90
自引率
6.70%
发文量
243
审稿时长
32 days
期刊介绍: The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.
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