A deep learning approach for cervical cord injury severity determination through axial and sagittal magnetic resonance imaging segmentation and classification.

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY European Spine Journal Pub Date : 2024-11-01 Epub Date: 2024-08-29 DOI:10.1007/s00586-024-08464-7
I Gusti Lanang Ngurah Agung Artha Wiguna, Yosi Kristian, Maria Florencia Deslivia, Rudi Limantara, David Cahyadi, Ivan Alexander Liando, Hendra Aryudi Hamzah, Kevin Kusuman, Dominicus Dimitri, Maria Anastasia, I Ketut Suyasa
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Abstract

Study design: Cross-sectional Database Study.

Objective: While the American Spinal Injury Association (ASIA) Impairment Scale is the standard for assessing spinal cord injuries (SCI), it has limitations due to subjectivity and impracticality. Advances in machine learning (ML) and image recognition have spurred research into their use for outcome prediction. This study aims to analyze deep learning techniques for identifying and classifying cervical SCI severity from MRI scans.

Methods: The study included patients with traumatic and nontraumatic cervical SCI admitted from 2019 to 2022. MRI images were labeled by two senior resident physicians. A deep convolutional neural network was trained using axial and sagittal cervical MRI images from the dataset. Model performance was assessed using Dice Score and IoU to measure segmentation accuracy by comparing predicted and ground truth masks. Classification accuracy was evaluated with the F1 Score, balancing false positives and negatives.

Result: In the axial spinal cord segmentation, we achieved a Dice score of 0.94 for and IoU score of 0.89. In the sagittal spinal cord segmentation, we obtained Dice score up to 0.9201 and IoU scores up to 0.8541. The model for axial image score classification gave a satisfactory result with an F1 score of 0.72 and AUC of 0.79.

Conclusion: Our models successfully identified cervical SCI on T2-weighted MR images with satisfactory performance. Further research is needed to develop more advanced models for predicting patient outcomes in SCI cases.

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通过轴向和矢状位磁共振成像分割和分类确定颈脊髓损伤严重程度的深度学习方法。
研究设计横断面数据库研究:虽然美国脊髓损伤协会(ASIA)损伤量表是评估脊髓损伤(SCI)的标准,但由于主观性和不实用性,该量表存在局限性。机器学习(ML)和图像识别技术的进步推动了将其用于结果预测的研究。本研究旨在分析从核磁共振成像扫描中识别和分类颈椎 SCI 严重程度的深度学习技术:研究对象包括 2019 年至 2022 年期间收治的创伤性和非创伤性颈椎 SCI 患者。MRI 图像由两名资深住院医师标注。使用数据集中的轴向和矢状颈椎 MRI 图像对深度卷积神经网络进行了训练。使用 Dice Score 和 IoU 评估模型性能,通过比较预测掩膜和地面实况掩膜来衡量分割准确性。分类准确性通过 F1 分数进行评估,平衡假阳性和假阴性:结果:在轴向脊髓分割中,我们的 Dice 得分为 0.94,IoU 得分为 0.89。在矢状脊髓分割中,我们获得了高达 0.9201 的 Dice 分数和 0.8541 的 IoU 分数。轴向图像评分分类模型的 F1 得分为 0.72,AUC 为 0.79,结果令人满意:我们的模型成功识别了 T2 加权磁共振图像上的颈椎 SCI,效果令人满意。需要进一步研究开发更先进的模型来预测 SCI 病例中患者的预后。
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来源期刊
European Spine Journal
European Spine Journal 医学-临床神经学
CiteScore
4.80
自引率
10.70%
发文量
373
审稿时长
2-4 weeks
期刊介绍: "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe
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