Challenges to suppressing placental permeability and reducing fetal toxicity of Angiotensin II Receptor Blockers by chemical modification with Polyethylene Glycol

IF 3 2区医学 Q2 DEVELOPMENTAL BIOLOGY Placenta Pub Date : 2024-09-02 DOI:10.1016/j.placenta.2024.07.011

Naoko Inaoka , Takayuki Iriyama , Tomoyuki Nishikawa , Kayoko Kanamitsu , Naoki Suto , Kosuke Yasuda , Takeshi Izawa , Jyoji Yamate , Keiichi Kumasawa , Yasushi Hirota , Yutaka Osuga

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通过聚乙二醇化学修饰抑制血管紧张素 II 受体阻滞剂的胎盘渗透性并降低其对胎儿毒性的挑战

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来源期刊

Placenta 医学-发育生物学

CiteScore

6.30

自引率

10.50%

发文量

391

审稿时长

78 days

期刊介绍： Placenta publishes high-quality original articles and invited topical reviews on all aspects of human and animal placentation, and the interactions between the mother, the placenta and fetal development. Topics covered include evolution, development, genetics and epigenetics, stem cells, metabolism, transport, immunology, pathology, pharmacology, cell and molecular biology, and developmental programming. The Editors welcome studies on implantation and the endometrium, comparative placentation, the uterine and umbilical circulations, the relationship between fetal and placental development, clinical aspects of altered placental development or function, the placental membranes, the influence of paternal factors on placental development or function, and the assessment of biomarkers of placental disorders.