Variability in the Treatment of High-Risk Type B Aortic Dissection at a Single Center

IF 2.3 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS American Journal of Cardiology Pub Date : 2024-08-27 DOI:10.1016/j.amjcard.2024.08.025
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Abstract

Although there are established high-risk features in acute type B aortic dissection (TBAD), its management is variable. This study characterizes complicated, uncomplicated, and high-risk TBAD in addition to their management and outcomes to gain insight into the actual significance of these high-risk features and the reality of real-world practice in managing TBAD. A retrospective review of 62 patients was conducted. Patient demographics, management, and outcomes were characterized and evaluated with Pearson's χ2 test, Fisher's exact test, or analysis of variance. Of the 32 high-risk TBADs, 66% (n = 21) received endovascular repair, 31% (n = 10) were medically managed, and 3% (n = 1) received hybrid (open and endovascular) repair. Refractory hypertension and pain (52%, n = 11) were the most common high-risk features in patients with high-risk TBAD who received endovascular repair. A maximum aortic diameter of >40 mm (67%, n = 6) was the most common high-risk feature in patients who received medical management. The most prevalent high-risk feature for all treatment groups in the high-risk TBADs was an aortic diameter of >40 mm (n = 16; 50%). Adverse postoperative outcomes were highest in the high-risk and complicated groups with endoleak as the most common adverse outcome (high-risk 12.9%, complicated 13.6%). Of the 62 patients, 47% (n = 26) had follow-up since their admission with an average follow-up time of 69 ± 166 days. The significance of high-risk features in the management of high-risk TBAD remains unclear. This single-center experience with managing acute TBAD reveals the reality of inadequate follow-up that may be specific to this disease process. This highlights a need to direct more efforts to assess long-term outcomes after treatment.

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单中心治疗高风险 B 型主动脉夹层的差异。
虽然急性 B 型主动脉夹层(TBAD)有既定的高风险特征,但其管理却不尽相同。本研究对复杂型、非复杂型和高风险型 TBAD 的特征及其处理和预后进行了分析,以深入了解这些高风险特征的实际意义以及处理 TBAD 的实际情况。该研究对 62 例患者进行了回顾性分析。采用皮尔逊χ 2 检验、费雪精确检验或方差分析(ANOVA)对患者的人口统计学特征、管理和结果进行了评估。在 32 例高风险 TBAD 中,66%(n=21)接受了血管内修复,31%(n=10)接受了药物治疗,3%(n=1)接受了混合(开放和血管内)修复。在接受血管内修复的高危 TBAD 患者中,难治性高血压和疼痛(52%,n=11)是最常见的高危特征。在接受内科治疗的患者中,主动脉最大直径大于 40 毫米(67%,人数=6)是最常见的高危特征。在所有治疗组中,主动脉直径大于 40 毫米(16 人;50%)是高危 TBAD 患者最常见的高危特征。术后不良后果在高危组和复杂组中最高,内漏是最常见的不良后果(高危组 12.9%,复杂组 13.6%)。在 62 名患者中,47%(26 人)在入院后进行了随访,平均随访时间为 69 ± 166 天。高风险特征在高风险 TBAD 管理中的意义尚不明确。这一单中心管理急性 TBAD 的经验揭示了随访不足的现实,而随访不足可能是这一疾病过程所特有的。这凸显出需要加大力度评估治疗后的长期疗效。
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来源期刊
American Journal of Cardiology
American Journal of Cardiology 医学-心血管系统
CiteScore
4.00
自引率
3.60%
发文量
698
审稿时长
33 days
期刊介绍: Published 24 times a year, The American Journal of Cardiology® is an independent journal designed for cardiovascular disease specialists and internists with a subspecialty in cardiology throughout the world. AJC is an independent, scientific, peer-reviewed journal of original articles that focus on the practical, clinical approach to the diagnosis and treatment of cardiovascular disease. AJC has one of the fastest acceptance to publication times in Cardiology. Features report on systemic hypertension, methodology, drugs, pacing, arrhythmia, preventive cardiology, congestive heart failure, valvular heart disease, congenital heart disease, and cardiomyopathy. Also included are editorials, readers'' comments, and symposia.
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