Patient, parent and professional expert perspectives on personalized regenerative implants: a qualitative focus group study.

IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Regenerative medicine Pub Date : 2024-01-01 Epub Date: 2024-09-02 DOI:10.1080/17460751.2024.2386214
Manon van Daal, Anne-Floor J de Kanter, Roel Jh Custers, Elena Martínez-Sanz, Annelien L Bredenoord, Nienke de Graeff
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Abstract

Background: Perspectives of patients, parents and professional experts on personalized regenerative implants for regenerative medicine purposes are largely unknown.Method: To better understand these perspectives, we conducted four focus groups with professional experts of mixed European nationality (n = 8), Dutch patients with regular implants (n = 8), Dutch and Belgian (n = 5) and Spanish (n = 8) parents of children with cleft palate.Results: Two overarching themes were identified: 'patient-centered research and care' and 'ambivalent attitudes toward personalized regenerative implants'.Discussion: The results reveal that stakeholders should adopt a participatory rather than an impairment discourse and address the ambivalence among professional experts, patients and parents.Conclusion: Considering stakeholder perspectives facilitates ethical and responsible development and use of personalized regenerative implants.

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患者、家长和专业专家对个性化再生植入物的看法:焦点小组定性研究。
背景:患者、家长和专业专家对用于再生医学目的的个性化再生植入物的看法大多不为人知:为了更好地了解这些观点,我们与欧洲混合国籍的专业专家(n = 8)、接受常规植入物的荷兰患者(n = 8)、荷兰和比利时(n = 5)以及西班牙(n = 8)腭裂患儿的父母进行了四次焦点小组讨论:结果:确定了两大主题:结果:确定了两个总体主题:"以患者为中心的研究和护理 "和 "对个性化再生植入体的矛盾态度":讨论:研究结果表明,利益相关者应采取参与性而非损害性的讨论方式,并解决专业专家、患者和家长的矛盾态度:结论:考虑利益相关者的观点有助于开发和使用个性化再生植入体,并使其符合道德规范和责任要求。
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来源期刊
Regenerative medicine
Regenerative medicine 医学-工程:生物医学
CiteScore
4.20
自引率
3.70%
发文量
82
审稿时长
6-12 weeks
期刊介绍: Regenerative medicine replaces or regenerates human cells, tissue or organs, to restore or establish normal function*. Since 2006, Regenerative Medicine has been at the forefront of publishing the very best papers and reviews covering the entire regenerative medicine sector. The journal focusses on the entire spectrum of approaches to regenerative medicine, including small molecule drugs, biologics, biomaterials and tissue engineering, and cell and gene therapies – it’s all about regeneration and not a specific platform technology. The journal’s scope encompasses all aspects of the sector ranging from discovery research, through to clinical development, through to commercialization. Regenerative Medicine uniquely supports this important area of biomedical science and healthcare by providing a peer-reviewed journal totally committed to publishing the very best regenerative medicine research, clinical translation and commercialization. Regenerative Medicine provides a specialist forum to address the important challenges and advances in regenerative medicine, delivering this essential information in concise, clear and attractive article formats – vital to a rapidly growing, multidisciplinary and increasingly time-constrained community. Despite substantial developments in our knowledge and understanding of regeneration, the field is still in its infancy. However, progress is accelerating. The next few decades will see the discovery and development of transformative therapies for patients, and in some cases, even cures. Regenerative Medicine will continue to provide a critical overview of these advances as they progress, undergo clinical trials, and eventually become mainstream medicine.
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Proliferation and differentiation of Wharton's jelly-derived mesenchymal stem cells on prgf-treated hydrogel scaffold. ATMP clinical trials in the UK. Industry updates from the field of stem cell research and regenerative medicine in September 2024. Correction. Industry updates from the field of stem cell research and regenerative medicine in August 2024.
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