Epidemiology of odontogenic tumours and selected cysts diagnosed at a single New Zealand oral pathology centre- A 15-year retrospective study.

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-12-01 Epub Date: 2024-08-30 DOI:10.1007/s10006-024-01290-7
Paul Kim, Benedict Seo, Haizal Hussaini, Alison M Rich, Harsha De Silva
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Abstract

Purpose: This research aimed to investigate the relative frequency of odontogenic tumours (OT) and selected odontogenic cysts in a single oral pathology center in New Zealand from 2008 to 2023.

Methods: Histopathological records from the Oral Pathology Centre, University of Otago (2008-2023) were examined to identify OT. Odontogenic keratocyst (OKC) and calcifying odontogenic cyst (COC), previously classified as OT were also included. Patient demographics, clinical details and histopathologic diagnoses were recorded. Data were analyzed using SPSS.

Results: Of the 34,225 biopsies over the 15-year period, 1.8% were identified as OTs, COC and OKCs and accounted for 47%, 1.5% and 51.5% respectively. The most prevalent OT types were odontoma (43.7%), ameloblastoma (27%) and cemento-ossifying fibroma (7.5%). Malignant OT, ameloblastic carcinoma, constituted 1.4% of OT. The average age at diagnosis for OKC, COC and OT patients were 48.2 ± 20.9, 33.7 ± 23.3 and 28.9 ± 19.3 years. Overall, male and mandibular site predilections were observed. Recurrence of OKC and ameloblastoma occurred in 15.2% and 13.7% of patients. The time for recurrence for OKC and Ameloblastoma were 61.7 ± 56.5 months and 122 ± 152 months respectively.

Conclusion: The demographic features and range of OT, COC and OKC in New Zealand align with those of other western countries. The study also confirms need for long term follow up for patient with OKC and ameloblastoma.

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新西兰一家口腔病理中心诊断的牙源性肿瘤和特定囊肿的流行病学--一项为期 15 年的回顾性研究。
目的:本研究旨在调查 2008 年至 2023 年期间新西兰单一口腔病理中心的牙源性肿瘤(OT)和特定牙源性囊肿的相对频率。方法:研究人员检查了奥塔哥大学口腔病理中心的组织病理学记录(2008-2023 年),以确定 OT。以前被归类为OT的牙源性角化囊肿(OKC)和钙化性牙源性囊肿(COC)也包括在内。记录了患者的人口统计学特征、临床细节和组织病理学诊断。数据使用 SPSS 进行分析:结果:在 15 年间的 34,225 例活检中,1.8% 的患者被确定为 OT、COC 和 OKC,分别占 47%、1.5% 和 51.5%。最常见的OT类型是牙体瘤(43.7%)、釉母细胞瘤(27%)和骨水泥化纤维瘤(7.5%)。恶性 OT(釉母细胞癌)占 OT 的 1.4%。OKC、COC和OT患者的平均诊断年龄分别为(48.2 ± 20.9)、(33.7 ± 23.3)和(28.9 ± 19.3)岁。总体而言,患者偏好男性和下颌部位。分别有 15.2% 和 13.7% 的患者出现 OKC 和母细胞瘤复发。OKC和母细胞瘤的复发时间分别为61.7 ± 56.5个月和122 ± 152个月:结论:新西兰OT、COC和OKC的人口特征和范围与其他西方国家一致。该研究还证实了对 OKC 和母细胞瘤患者进行长期随访的必要性。
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来源期刊
Oral and Maxillofacial Surgery-Heidelberg
Oral and Maxillofacial Surgery-Heidelberg DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.20
自引率
5.60%
发文量
118
期刊介绍: Oral & Maxillofacial Surgery founded as Mund-, Kiefer- und Gesichtschirurgie is a peer-reviewed online journal. It is designed for clinicians as well as researchers.The quarterly journal offers comprehensive coverage of new techniques, important developments and innovative ideas in oral and maxillofacial surgery and interdisciplinary aspects of cranial, facial and oral diseases and their management. The journal publishes papers of the highest scientific merit and widest possible scope on work in oral and maxillofacial surgery as well as supporting specialties. Practice-oriented articles help improve the methods used in oral and maxillofacial surgery.Every aspect of oral and maxillofacial surgery is fully covered through a range of invited review articles, clinical and research articles, technical notes, abstracts, and case reports. Specific topics are: aesthetic facial surgery, clinical pathology, computer-assisted surgery, congenital and craniofacial deformities, dentoalveolar surgery, head and neck oncology, implant dentistry, oral medicine, orthognathic surgery, reconstructive surgery, skull base surgery, TMJ and trauma.Time-limited reviewing and electronic processing allow to publish articles as fast as possible. Accepted articles are rapidly accessible online.Clinical studies submitted for publication have to include a declaration that they have been approved by an ethical committee according to the World Medical Association Declaration of Helsinki 1964 (last amendment during the 52nd World Medical Association General Assembly, Edinburgh, Scotland, October 2000). Experimental animal studies have to be carried out according to the principles of laboratory animal care (NIH publication No 86-23, revised 1985).
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